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Last Updated: December 22, 2024

AMIDATE Drug Patent Profile


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When do Amidate patents expire, and when can generic versions of Amidate launch?

Amidate is a drug marketed by Hospira and is included in one NDA.

The generic ingredient in AMIDATE is etomidate. There are six drug master file entries for this compound. Fourteen suppliers are listed for this compound. Additional details are available on the etomidate profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Amidate

A generic version of AMIDATE was approved as etomidate by HIKMA on November 4th, 1996.

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Summary for AMIDATE
Drug patent expirations by year for AMIDATE
Drug Prices for AMIDATE

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Recent Clinical Trials for AMIDATE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
New Hanover Regional Medical CenterPhase 4
South East Area Health Education Center, Wilmington, NCPhase 4
University of California, DavisPhase 4

See all AMIDATE clinical trials

Pharmacology for AMIDATE
Drug ClassGeneral Anesthetic
Physiological EffectGeneral Anesthesia

US Patents and Regulatory Information for AMIDATE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Hospira AMIDATE etomidate INJECTABLE;INJECTION 018227-001 Sep 7, 1982 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

AMIDATE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Etomidate (Amidate)

Market Introduction and Definition

Etomidate, commonly known by its brand name Amidate, is a short-acting intravenous anesthetic agent used for the induction of general anesthesia and for sedation in critical care settings. Its market dynamics are influenced by several key factors, including the increasing demand for effective anesthetic drugs, advancements in healthcare infrastructure, and the growing prevalence of surgical procedures.

Market Size and Forecast

The global etomidate market has been valued at significant levels and is projected to grow steadily over the coming years. Here are some key financial projections:

  • 2023 Valuation: The etomidate market size was valued at approximately USD 2.3 billion to USD 5 billion, depending on the source and specific market segment[3][4].
  • Forecast Period: The market is expected to grow from 2024 to 2033, with a Compound Annual Growth Rate (CAGR) of around 3.2% to 3.6%[1][4].
  • Projected Value by 2033: The market is anticipated to reach USD 3.2 billion to USD 8.59 billion by 2033, depending on the forecast model[3][4].

Growth Drivers

Several factors are driving the growth of the etomidate market:

Increasing Demand for Anesthetic Drugs

The rising number of surgical procedures globally is a significant driver. According to the Johnson & Johnson 2022 Health for Humanity Report, approximately 313 million surgical procedures are undertaken worldwide each year, which necessitates a higher demand for effective anesthetics like etomidate[4].

Growing Healthcare Infrastructure

The expansion of healthcare infrastructure, particularly in emerging markets, is boosting the demand for reliable and efficient anesthetic agents. Governments and private sectors are investing heavily in enhancing medical facilities and accessibility, which is favorable for the etomidate market[4].

Favorable Hemodynamic Profile

Etomidate is preferred for its rapid onset and short duration of action, along with its minimal cardiovascular effects, making it an ideal choice for emergency and short-term surgical procedures[4].

Research and Development

Ongoing research into new formulations and delivery methods of etomidate is expected to further drive market growth. The development of fat emulsion formulations, for example, has reduced side effects and improved the drug's efficacy[1].

Market Segmentation

The etomidate market is segmented in several ways:

By Product Type

  • Induction Agent: Etomidate is widely used as an induction agent due to its quick onset and short duration of action.
  • Fat Emulsion: This segment is expected to grow significantly due to the lesser side effects associated with fat emulsion formulations and their role in energy metabolism during operations[1][4].

By End User

  • Hospitals: Hospitals are a major segment, driven by the high volume of surgical procedures.
  • Ambulatory Surgical Centers: These centers are expected to hold a significant share due to the high usage of etomidate in trauma and cardiovascular emergencies.
  • Other End Users: This includes clinics and other healthcare facilities[1][4].

By Geography

  • North America: This region is expected to contribute significantly due to advanced healthcare infrastructure, high healthcare spending, and a high incidence of chronic conditions.
  • Asia-Pacific: This region is set to account for the largest revenue share by 2036, driven by favorable government policies and rapidly growing healthcare infrastructure[1][4].

Regional Market Outlook

North America

The etomidate market in North America is driven by factors such as advanced healthcare infrastructure, an increase in surgical operations, and a high incidence of chronic conditions. The U.S. plays a crucial role due to its high healthcare spending and well-established medical facilities[4].

Asia-Pacific

The Asia-Pacific region is expected to dominate the market due to favorable government policies and the rapid growth of healthcare infrastructure. This region's growing demand for effective anesthetics in emergency and surgical procedures is a key driver[1][4].

Challenges

While the etomidate market is growing, it faces some challenges:

Side Effects

Despite the advantages of fat emulsion formulations, etomidate can still have side effects such as adrenal suppression, which may limit its use in some cases[4].

Regulatory Environment

Changes in regulatory policies and stringent approval processes can impact the market growth. However, the current favorable regulatory environment, especially in regions like Asia-Pacific, is supporting the market's expansion[1].

Key Market Players

Several pharmaceutical companies are key players in the etomidate market:

  • Teva
  • Johnson & Johnson
  • Esteve Pharma
  • Krka
  • AbbVie
  • Abbott
  • Mylan
  • Luitpold Pharmaceuticals
  • Par Sterile Products
  • Zydus[4].

Illustrative Statistics

  • Surgical Procedures: Approximately 313 million surgical procedures are undertaken worldwide each year[4].
  • Healthcare Spending: OECD health spending as a share of GDP has been increasing, reaching 9.2% in 2022[4].
  • Animal Testing: In 2019, the United States used more than 790,000 animals for research, with guinea pigs accounting for the largest share[1].

Quotes from Industry Experts

"Etomidate is gaining traction as a preferred choice in emerging markets due to its stability and minimal cardiovascular effects," - Industry Analyst[4].

Highlight

"Etomidate is preferred for its rapid onset and short duration of action, along with its minimal cardiovascular effects, making it an ideal choice for emergency and short-term surgical procedures."[4]

Key Takeaways

  • The etomidate market is driven by the increasing demand for effective anesthetic drugs and the growing number of surgical procedures.
  • The market is segmented by product type, end user, and geography, with the Asia-Pacific region expected to dominate.
  • Key players include major pharmaceutical companies like Teva, Johnson & Johnson, and Krka.
  • The market faces challenges such as side effects and regulatory environments but is supported by favorable government policies and growing healthcare infrastructure.

FAQs

  1. What is the primary use of etomidate in medical settings? Etomidate is primarily used as an induction agent for general anesthesia and for sedation in critical care settings due to its rapid onset and short duration of action.

  2. Which region is expected to dominate the etomidate market by 2036? The Asia-Pacific region is expected to account for the largest revenue share by 2036, driven by favorable government policies and rapidly growing healthcare infrastructure.

  3. What are the key drivers of the etomidate market growth? The key drivers include the increasing demand for anesthetic drugs, growing healthcare infrastructure, and the favorable hemodynamic profile of etomidate.

  4. Which formulation of etomidate is expected to grow significantly? The fat emulsion formulation is expected to grow significantly due to its lesser side effects and role in energy metabolism during operations.

  5. Who are the major players in the etomidate market? Major players include Teva, Johnson & Johnson, Esteve Pharma, Krka, AbbVie, Abbott, Mylan, Luitpold Pharmaceuticals, Par Sterile Products, and Zydus.

Sources

  1. Research Nester: Etomidate Market Size, Forecast Report 2036
  2. Accenture: AMIDA Transition Support Final Report
  3. Market Research Intellect: Etomidate Injection Market Size and Projections
  4. Allied Market Research: Etomidate Market Size, Share and Growth Report, 2033
  5. SAGE Journals: Phosphoramidates and phosphonamidates (ProTides) with antiviral activity

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