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Last Updated: December 23, 2024

ANGIO-CONRAY Drug Patent Profile


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Which patents cover Angio-conray, and what generic alternatives are available?

Angio-conray is a drug marketed by Mallinckrodt and is included in one NDA.

The generic ingredient in ANGIO-CONRAY is iothalamate sodium. There is one drug master file entry for this compound. Additional details are available on the iothalamate sodium profile page.

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Summary for ANGIO-CONRAY
US Patents:0
Applicants:1
NDAs:1
Raw Ingredient (Bulk) Api Vendors: 19
Patent Applications: 587
DailyMed Link:ANGIO-CONRAY at DailyMed
Drug patent expirations by year for ANGIO-CONRAY

US Patents and Regulatory Information for ANGIO-CONRAY

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Mallinckrodt ANGIO-CONRAY iothalamate sodium INJECTABLE;INJECTION 013319-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

ANGIO-CONRAY Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Conray

Introduction

Conray, a diagnostic radiopaque medium containing iothalamate meglumine, is widely used in various medical imaging procedures. Understanding its market dynamics and financial trajectory is crucial for stakeholders, including healthcare providers, investors, and pharmaceutical companies.

Market Indications and Uses

Conray is indicated for a broad range of medical imaging procedures, including excretory urography, cerebral angiography, peripheral arteriography, venography, arthrography, direct cholangiography, and contrast enhancement in computed tomography (CT) scans[4][5].

Competitive Landscape

The market for radiopaque contrast media is competitive, with several players offering similar products. However, Conray's versatility and the breadth of its indications position it as a significant player in this market. Companies like AngioDynamics, which have a strong focus on interventional devices and diagnostic products, often collaborate with leading physicians to enhance their product lines and maintain market share[3].

Financial Performance

The financial performance of Conray is closely tied to the overall financial health of its manufacturing and distributing companies. For instance, AngioDynamics, a company involved in the acquisition and development of various medical technologies, has seen fluctuations in its financial performance due to acquisitions, market conditions, and regulatory factors.

Acquisitions and Expansion

AngioDynamics' acquisition of companies like FlowMedica and Diomed has expanded its product portfolio, including diagnostic and therapeutic products. These acquisitions, while initially costly, have strengthened the company's position in the market for vascular and oncology treatments. For example, the acquisition of Diomed's assets for approximately $11.1 million enhanced AngioDynamics' offerings in the treatment of varicose veins[3].

Revenue and Market Share

The revenue generated by Conray contributes to the overall financial health of its parent company. While specific revenue figures for Conray are not publicly disclosed, the product's wide range of indications and its use in critical diagnostic procedures suggest it is a significant revenue generator. AngioDynamics' focus on premium performance products and its collaboration with leading interventional physicians help maintain a strong market share[3].

Regulatory Environment

The regulatory environment plays a crucial role in the market dynamics of Conray. Regulatory approvals and compliance with safety standards are essential for the continued use and marketing of the product. For instance, Conray is contraindicated in patients hypersensitive to the drug or its components, and its use must be carefully monitored, especially in patients with impaired renal function[4][5].

Clinical Pharmacology and Safety

Conray's pharmacokinetics, including its rapid distribution and elimination phases, are well-documented. The product is excreted unchanged in the urine by glomerular filtration, with alpha and beta half-lives of approximately 10 and 90 minutes, respectively, in patients with normal renal function. This profile is critical for its safe and effective use in various diagnostic procedures[4][5].

Market Trends and Future Outlook

The demand for diagnostic radiopaque media like Conray is influenced by advances in medical imaging technologies and the increasing need for precise diagnostic tools. Here are some key trends:

Technological Advancements

Advances in CT scanning and digital subtraction angiography have enhanced the utility of Conray, allowing for better visualization and diagnosis of various conditions. Continuous or multiple scans during the first 30 to 90 seconds post-injection (dynamic CT scanning) provide significant diagnostic benefits[4].

Growing Need for Diagnostic Procedures

The increasing prevalence of diseases that require advanced diagnostic imaging, such as vascular diseases and cancers, drives the demand for products like Conray. The aging population and the rising incidence of chronic diseases further contribute to this demand.

Cost and Accessibility

The cost of Conray and other diagnostic contrast media can be a significant factor in their adoption. Efforts to make these products more accessible and affordable, especially in developing markets, could expand their market reach.

Key Takeaways

  • Broad Indications: Conray is used in a wide range of medical imaging procedures.
  • Competitive Market: The market for radiopaque contrast media is competitive, with several players.
  • Financial Performance: Tied to the financial health of its manufacturing and distributing companies, with significant contributions from acquisitions and market expansion.
  • Regulatory Compliance: Critical for the continued use and marketing of Conray.
  • Clinical Pharmacology: Well-documented pharmacokinetics ensure safe and effective use.
  • Market Trends: Driven by technological advancements, growing need for diagnostic procedures, and cost considerations.

FAQs

What are the primary indications for Conray?

Conray is indicated for use in excretory urography, cerebral angiography, peripheral arteriography, venography, arthrography, direct cholangiography, and contrast enhancement in computed tomography (CT) scans[4][5].

How is Conray administered?

Conray can be administered through intravascular injection, intravenous bolus injection, or rapid infusion, depending on the specific procedure[1][4].

What are the contraindications for Conray?

Conray is contraindicated in patients who are hypersensitive to the drug or any ingredient in the formulation or component of the container[1][4].

How does Conray affect patients with impaired renal function?

In patients with impaired renal function, diagnostic opacification may be achieved only after prolonged periods due to slower excretion of the contrast medium[4][5].

What are the potential side effects of Conray?

While specific side effects are not detailed here, it is important to monitor patients for any adverse reactions, especially those with hypersensitivity or impaired renal function[1][4].

Sources

  1. PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION - Conray 60, Conray 43, Conray 30[1].
  2. Matching Michigan: A 2-year stepped interventional programme to prevent CVC-BSIs - Not directly related to Conray but provides context on medical interventions[2].
  3. AngioDynamics, Inc. - Investor information and company acquisitions[3].
  4. Conray: Package Insert / Prescribing Information - Drugs.com[4].
  5. Conray - accessdata.fda.gov - FDA Label[5].

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