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Last Updated: December 22, 2024

APREPITANT Drug Patent Profile


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When do Aprepitant patents expire, and when can generic versions of Aprepitant launch?

Aprepitant is a drug marketed by Glenmark Speclt, Sandoz, and Torrent. and is included in three NDAs.

The generic ingredient in APREPITANT is aprepitant. There are twenty-six drug master file entries for this compound. Five suppliers are listed for this compound. Additional details are available on the aprepitant profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Aprepitant

A generic version of APREPITANT was approved as aprepitant by SANDOZ on September 24th, 2012.

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Drug patent expirations by year for APREPITANT
Drug Prices for APREPITANT

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Recent Clinical Trials for APREPITANT

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SponsorPhase
Hubei Cancer HospitalN/A
Second Affiliated Hospital, School of Medicine, Zhejiang UniversityPhase 4
Guangxi Medical UniversityPhase 3

See all APREPITANT clinical trials

Paragraph IV (Patent) Challenges for APREPITANT
Tradename Dosage Ingredient Strength NDA ANDAs Submitted Submissiondate
APONVIE Intravenous Emulsion aprepitant 32 mg/4.4 mL 216457 1 2023-11-07
CINVANTI Intravenous Emulsion aprepitant 130 mg/18 mL 209296 1 2022-04-29
EMEND for Oral Suspension aprepitant 125 mg/Kit 207865 1 2016-11-23
EMEND Capsule aprepitant 40 mg, 80 mg and 125 mg 021549 1 2008-11-03

US Patents and Regulatory Information for APREPITANT

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Glenmark Speclt APREPITANT aprepitant CAPSULE;ORAL 207777-001 Oct 12, 2017 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Torrent APREPITANT aprepitant CAPSULE;ORAL 211835-001 Oct 21, 2020 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Sandoz APREPITANT aprepitant CAPSULE;ORAL 090999-001 Sep 24, 2012 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Torrent APREPITANT aprepitant CAPSULE;ORAL 211835-002 Oct 21, 2020 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for APREPITANT

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Merck Sharp & Dohme B.V. Emend aprepitant EMEA/H/C/000527
Emend 40 mg hard capsules is indicated for the prevention of postoperative nausea and vomiting (PONV) in adults.Emend is also available as 80 mg and 125 mg hard capsules for the prevention of nausea and vomiting associated with highly and moderately emetogenic cancer chemotherapy in adults and adolescents from the age of 12 (see separate Summary of Product Characteristics).Emend is also available as 165 mg hard capsules for the prevention of acute and delayed nausea and vomiting associated with highly emetogenic cisplatin based cancer chemotherapy in adults and the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy in adults.Emend is also available as powder for oral suspension for the prevention of nausea and vomiting associated with highly and moderately emetogenic cancer chemotherapy in children, toddlers and infants from the age of 6 months to less than 12 years.Emend 80 mg, 125 mg, 165 mg hard capsules and Emend powder for oral suspension are given as part of combination therapy.
Authorised no no no 2003-11-11
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

APREPITANT Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Aprepitant

Market Overview

Aprepitant, a drug widely recognized for its efficacy in managing chemotherapy-induced nausea and vomiting (CINV), is a pivotal component of modern cancer care. The market for aprepitant is characterized by several key dynamics that influence its growth and financial trajectory.

Key Drivers of the Aprepitant Market

Growing Prevalence of Cancer

The increasing incidence of cancer globally is a significant driver for the aprepitant market. As cancer therapies become more advanced and common, the need for effective antiemetic drugs like aprepitant rises[4].

Expanding Applications

Aprepitant's use is not limited to CINV; it is also effective in treating postoperative nausea and other forms of acute nausea. This broadening of indications contributes to the market's growth[4].

Advancements in Healthcare Infrastructure

Improvements in healthcare infrastructure, particularly in regions like North America, Europe, and the Asia-Pacific, enhance the accessibility and affordability of aprepitant, driving market expansion[1].

Increasing Awareness and Adoption

Growing awareness among patients and healthcare professionals about the benefits of aprepitant in preventing nausea and vomiting associated with chemotherapy and surgery is another key driver. This increased awareness leads to higher adoption rates[4].

Market Segmentation

By Product Type

The aprepitant market is segmented into various product types, including capsules, injectable solutions, tablets, and oral suspensions. Each form has its own market share and growth trajectory, influenced by patient preferences and clinical needs[4].

By Application

The market is also segmented by application, with the primary segments being chemotherapy-induced nausea, postoperative nausea, and acute nausea. The chemotherapy-induced nausea segment dominates the market due to the high prevalence of cancer[4].

By Region

Geographically, the market is led by North America, followed closely by Europe. The Asia-Pacific region is experiencing rapid growth due to rising awareness and improving healthcare access. Emerging regions like Latin America and the Middle East also show promising potential[1].

Financial Trajectory

Market Size and Growth

The global aprepitant market size was valued at USD 1.2 billion in 2023 and is projected to reach USD 1.9 billion by 2031, growing at a Compound Annual Growth Rate (CAGR) of 5.5% from 2024 to 2031[4].

Revenue Projections

The market's financial growth is supported by the increasing demand for aprepitant in various therapeutic areas. For instance, the global CINV existing and pipeline drugs market, which includes aprepitant, is expected to grow from USD 1.9 billion in 2021 to USD 3.2 billion by 2031, at a CAGR of 5.8%[3].

Key Players and Competitive Landscape

Major Market Players

The aprepitant market is competitive, with key players such as Merck & Co., Heron Therapeutics, Sandoz, and Glenmark Pharmaceuticals driving innovation and growth. These companies are involved in research and development to enhance aprepitant formulations and explore new therapeutic areas[1].

Strategic Collaborations and Expansions

Industry players are forging strategic collaborations and expanding their product portfolios to meet the rising demand for aprepitant. For example, Heron Therapeutics has seen positive momentum in its oncology care franchise, which includes aprepitant, and has received FDA approvals for expanded indications[2].

Impact of Technological Innovations

AI-Driven Drug Discovery

The adoption of new technologies such as AI-driven drug discovery and precision medicine is reshaping the aprepitant market. These innovations facilitate the development of more effective antiemetic drugs, enhancing patient outcomes[1].

Precision Medicine

Precision medicine approaches are also contributing to the market's growth by allowing for more targeted and effective treatments, which can include personalized antiemetic regimens using aprepitant[1].

Regional Market Analysis

North America

North America dominates the aprepitant market due to its robust healthcare infrastructure and the high prevalence of cancer cases. The region is expected to continue leading the market during the forecast period[1].

Europe

Europe follows closely behind North America, with significant research initiatives and a growing aging population driving the demand for aprepitant[1].

Asia-Pacific

The Asia-Pacific region is experiencing rapid market expansion fueled by rising awareness about CINV and improving healthcare access. Countries like Japan, China, and India are key contributors to this growth[1].

Latin America and Middle East

Emerging regions such as Latin America and the Middle East show promising potential, with pharmaceutical companies actively venturing into these markets to tap into their burgeoning patient populations[1].

Financial Performance of Key Players

Heron Therapeutics

Heron Therapeutics, a key player in the aprepitant market, reported increased sales trajectory in both its acute care and oncology care franchises in the fourth quarter of 2023. The company reaffirmed its financial guidance for 2024, indicating a positive financial outlook[2].

Market Attractiveness Analysis

By Major Drugs

The market attractiveness analysis by major drugs, including aprepitant, shows that these drugs are highly attractive due to their efficacy and the growing demand for antiemetic treatments[3].

By Region

The market attractiveness analysis by region highlights the potential of emerging markets like the Asia-Pacific and Latin America, which are expected to contribute significantly to the market's growth in the coming years[3].

Challenges and Restraints

Pricing and Reimbursement

Pricing strategies and reimbursement support are crucial factors influencing the affordability and accessibility of aprepitant therapy. Financial services, including insurance coverage, play a significant role in making the drug accessible to patients[1].

Regulatory Approvals

The need for regulatory approvals and the complexity of the approval process can act as restraints to market growth. However, recent approvals, such as the FDA approval for Heron Therapeutics' supplemental New Drug Application (sNDA), indicate a positive regulatory environment[2].

Conclusion

The aprepitant market is poised for significant growth driven by the increasing prevalence of cancer, expanding applications, and advancements in healthcare infrastructure. Key players are driving innovation, and technological advancements are enhancing patient outcomes. However, challenges such as pricing and regulatory approvals need to be navigated to fully realize the market's potential.

Key Takeaways

  • The global aprepitant market is expected to grow from USD 1.2 billion in 2023 to USD 1.9 billion by 2031.
  • North America dominates the market, followed by Europe and the Asia-Pacific region.
  • Key drivers include the growing prevalence of cancer, expanding applications, and advancements in healthcare infrastructure.
  • Technological innovations such as AI-driven drug discovery and precision medicine are enhancing market growth.
  • Pricing and reimbursement strategies are critical for market accessibility.

FAQs

What is the primary use of aprepitant?

Aprepitant is primarily used to manage chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea.

Who are the key players in the aprepitant market?

Key players include Merck & Co., Heron Therapeutics, Sandoz, and Glenmark Pharmaceuticals.

What is the expected growth rate of the aprepitant market?

The aprepitant market is expected to grow at a CAGR of 5.5% from 2024 to 2031.

Which region dominates the aprepitant market?

North America dominates the aprepitant market due to its robust healthcare infrastructure and high prevalence of cancer cases.

What are the major challenges facing the aprepitant market?

Major challenges include pricing strategies, reimbursement support, and regulatory approvals.

Sources

  1. Aprepitant Market Analysis and Global Regional Outlook - OpenPR
  2. Heron Therapeutics Announces Fourth Quarter and Full-Year 2023 - Heron Therapeutics
  3. CINV Existing and Pipeline Drugs Market Analysis Report 2031 - Transparency Market Research
  4. Aprepitant Market Size and Projections - Market Research Intellect

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