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Last Updated: March 27, 2025

ARESTOCAINE HYDROCHLORIDE Drug Patent Profile


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When do Arestocaine Hydrochloride patents expire, and when can generic versions of Arestocaine Hydrochloride launch?

Arestocaine Hydrochloride is a drug marketed by Solvay and is included in two NDAs.

The generic ingredient in ARESTOCAINE HYDROCHLORIDE is levonordefrin; mepivacaine hydrochloride. There are two drug master file entries for this compound. Additional details are available on the levonordefrin; mepivacaine hydrochloride profile page.

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Summary for ARESTOCAINE HYDROCHLORIDE
Drug patent expirations by year for ARESTOCAINE HYDROCHLORIDE

US Patents and Regulatory Information for ARESTOCAINE HYDROCHLORIDE

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Solvay ARESTOCAINE HYDROCHLORIDE mepivacaine hydrochloride INJECTABLE;INJECTION 084777-002 Apr 18, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Solvay ARESTOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN levonordefrin; mepivacaine hydrochloride INJECTABLE;INJECTION 085010-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 2 of 2 entries

Articaine Hydrochloride Market Dynamics and Financial Trajectory

Market Overview

The articaine hydrochloride market is experiencing significant growth, driven by several key factors. Here is a comprehensive look at the market dynamics and financial trajectory of this important local anesthetic.

Market Size and Growth

As of 2022, the articaine hydrochloride market was valued at USD 1,128.33 million. It is projected to grow to USD 2,135.33 million by 2031, with a Compound Annual Growth Rate (CAGR) of 8.3% during the forecast period of 2024-2031[1].

Drivers of Market Growth

Several factors are driving the growth of the articaine hydrochloride market:

Effective Dental Treatments

Articaine hydrochloride is preferred by doctors due to its rapid action and superior efficacy over other anesthetic medications. It has a higher concentration (4% vs 2% for lidocaine) and better liposolubility, allowing it to diffuse more effectively through nerve cell lipid membranes and surrounding tissues[2].

Rising Incidence of Dental Problems

The increasing incidence of dental problems, such as dental caries and periodontal diseases, particularly among the growing elderly population and those consuming junk food, is a significant driver. This has led to an increased demand for effective dental anesthetics like articaine hydrochloride[1].

Growing Disposable Income and Cosmetic Dentistry

The rise in disposable income and the growing trend of cosmetic dentistry are also supporting market expansion. More people are seeking dental procedures, which in turn increases the demand for articaine hydrochloride[1].

Technological Advancements

Advances in pharmaceutical delivery technology, such as the use of computer-controlled local anesthetic delivery (CCLAD) systems, have improved patient tolerance and efficacy, further propelling market growth[1].

End User Segmentation

The articaine hydrochloride market is segmented based on end users, including:

Dental Clinics

Dental clinics are the largest segment, driven by the high adoption of new technologies and the frequent use of articaine hydrochloride in various dental procedures[1].

Hospitals

Hospitals are the fastest-growing segment, reflecting the increasing number of dental procedures performed in hospital settings[1].

Academics & Research Institutes

These institutions also play a role, particularly in the development and testing of new dental anesthesia techniques and products[1].

Regional Market Analysis

The market is segmented into several regions:

Asia-Pacific

This region is experiencing the quickest growth rate, with countries like China, Japan, and India driving the expansion. Australia also holds a significant position due to its high adoption of new technology in dentistry[1].

North America and Europe

These regions are also significant, with well-established healthcare systems and a high demand for dental procedures[1].

Latin America, Middle East, and Africa

These regions are emerging as important growth areas due to the rising number of dental procedures, expansion of the healthcare system, and increasing awareness of modern dental anesthesia techniques[1].

Competitive Landscape

Major international pharmaceutical companies such as Septodont, Dentsply Sirona, Pierrel Pharma, 3M Company, and Anhui BBCA Pharmaceutical Co., Ltd. are actively competing in the market. These companies are focusing on product innovation, strategic partnerships, and geographical expansion to capture market share[1].

Challenges and Restraints

Despite the growth, there are several challenges:

Unfavorable Reimbursement Regulations

Regulatory constraints and unfavorable reimbursement policies are expected to hinder market expansion[1].

High Cost of Dental Procedures

The high cost of dental procedures is another factor that could impede market growth[1].

Availability of Substitute Products

The availability and use of substitute local anesthetics like lidocaine, prilocaine, mepivacaine, and bupivacaine could also restrain the market's growth[1].

Safety and Efficacy

Articaine hydrochloride has a superior safety profile compared to other local anesthetics:

Faster Metabolism

Articaine is metabolized primarily through hydrolysis of the ester side chain in the plasma and excreted via the kidneys, resulting in a shorter elimination half-life (27-42 minutes) compared to lidocaine (90 minutes)[2].

Lower Risk of Paresthesia

Studies have shown that articaine does not have a higher risk of paresthesia compared to other local anesthetics, and the risk is often attributed to the injection technique rather than the anesthetic itself[2].

Future Prospects

Ongoing research and development efforts are expected to yield novel opportunities for the industry. The development of new dental anesthesia delivery systems and the growing awareness of modern dental anesthesia techniques in emerging markets will continue to drive market growth[1].

Key Takeaways

  • The articaine hydrochloride market is projected to grow significantly, driven by its superior efficacy and safety profile.
  • The market is segmented by application, end user, and region, with dental clinics being the largest segment.
  • Asia-Pacific is the fastest-growing region, driven by countries like China, Japan, and India.
  • Despite growth, the market faces challenges such as unfavorable reimbursement regulations and the high cost of dental procedures.
  • Ongoing R&D and technological advancements are expected to further propel market growth.

FAQs

What is the current market size of articaine hydrochloride?

The articaine hydrochloride market was valued at USD 1,128.33 million in 2022[1].

What is the projected growth rate of the articaine hydrochloride market?

The market is projected to grow at a CAGR of 8.3% from 2024 to 2031[1].

Which region is experiencing the fastest growth in the articaine hydrochloride market?

The Asia-Pacific region is experiencing the fastest growth, driven by countries like China, Japan, and India[1].

What are the main drivers of the articaine hydrochloride market?

The main drivers include its superior efficacy, rising incidence of dental problems, growing disposable income, and technological advancements in pharmaceutical delivery[1].

What are the challenges facing the articaine hydrochloride market?

Challenges include unfavorable reimbursement regulations, the high cost of dental procedures, and the availability of substitute products[1].

How does articaine hydrochloride compare to lidocaine in terms of safety and efficacy?

Articaine hydrochloride has a higher concentration, faster onset, longer duration, and a shorter elimination half-life compared to lidocaine, making it safer and more effective[2].

Sources

  1. SkyQuestT: Articaine Hydrochloride Market Size, Growth & Trends Report | 2031
  2. Today's RDH: Articaine vs. Lidocaine: A Comparison of Local Anesthetics
  3. Research Dive: Local Anesthesia Drugs Market Size & Industry Trends: 2031
  4. Market Research Future: Articaine Hydrochloride Market Size, Growth and Forecast – 2032
  5. Medsafe: Application to widen the classification for topical oral - Medsafe

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