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Last Updated: December 22, 2024

ATRIDOX Drug Patent Profile


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Which patents cover Atridox, and when can generic versions of Atridox launch?

Atridox is a drug marketed by Den-mat and is included in one NDA.

The generic ingredient in ATRIDOX is doxycycline hyclate. There are twenty-eight drug master file entries for this compound. Seventy-four suppliers are listed for this compound. Additional details are available on the doxycycline hyclate profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Atridox

A generic version of ATRIDOX was approved as doxycycline hyclate by EPIC PHARMA LLC on November 8th, 1982.

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Summary for ATRIDOX
US Patents:0
Applicants:1
NDAs:1
Raw Ingredient (Bulk) Api Vendors: 55
Clinical Trials: 2
Patent Applications: 438
What excipients (inactive ingredients) are in ATRIDOX?ATRIDOX excipients list
DailyMed Link:ATRIDOX at DailyMed
Drug patent expirations by year for ATRIDOX
Recent Clinical Trials for ATRIDOX

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
National Institute of Dental and Craniofacial Research (NIDCR)Phase 2
The Forsyth InstitutePhase 2
Milton S. Hershey Medical CenterN/A

See all ATRIDOX clinical trials

US Patents and Regulatory Information for ATRIDOX

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Den-mat ATRIDOX doxycycline hyclate SYSTEM, EXTENDED RELEASE;PERIODONTAL 050751-001 Sep 3, 1998 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

ATRIDOX Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for ATRIDOX

Introduction to ATRIDOX

ATRIDOX, a formulation of doxycycline hyclate, is a significant player in the periodontal therapeutics market. It is used to treat periodontitis, a chronic bacterial infection of the gums and bone supporting the teeth. Here, we will delve into the market dynamics and financial trajectory of ATRIDOX.

Market Segmentation and Product Type

ATRIDOX falls under the category of local antibiotics, which are gaining preference over systemic antibiotics due to their site-specific distribution, low dose requirements, and reduced side effects. Local antibiotics, such as ATRIDOX, are administered as mouth rinses, gels, or tiny chips placed into the gingival sulcus, offering superior therapeutic outcomes[2].

Market Size and Growth

The global periodontal therapeutics market, which includes ATRIDOX, was valued at $2.2 billion in 2022 and is projected to grow at a CAGR of 8.3% to reach $4.5 billion by 2031. This growth is driven by the increasing prevalence of periodontal diseases, rising cases of diabetes, and an aging global population[2].

Regional Market Performance

North America, particularly the United States, holds the largest market share for periodontal therapeutics, including ATRIDOX. This is attributed to the high prevalence of periodontitis, with the CDC estimating that 50% of people aged 30 and older have periodontitis. The region's advanced healthcare infrastructure, high investment in R&D, and favorable regulatory environment also contribute to its dominance[2].

Distribution Channels

ATRIDOX is available through various distribution channels, including hospitals, retail pharmacies, drug stores, and e-commerce platforms. The ease of access through these channels has contributed to its market penetration and growth. Hospitals and retail pharmacies remain the primary distribution channels, but e-commerce is gaining traction due to its convenience and reach[1][4].

Competitive Landscape

The periodontal therapeutics market is competitive, with key players such as Eli Lilly and Company, Pfizer Inc., Dexcel Pharma, Teva Pharmaceuticals Industries Ltd., and Emergent Biosolutions, Inc. ATRIDOX, being a product of Dexcel Pharma, competes with other local antibiotics like Arestin and Periochip. The competitive landscape is driven by innovation, regulatory approvals, and marketing strategies[2].

Regulatory Challenges

Developing and approving new periodontal therapeutics, including ATRIDOX, is subject to regulatory challenges such as lengthy approval processes, complex regulations, and high clinical trial and compliance costs. These challenges can hinder innovation and limit the availability of new treatment options. However, ATRIDOX has already navigated these challenges and is approved for use in treating periodontitis[2].

Clinical Efficacy and Safety

ATRIDOX has demonstrated clinical efficacy in reducing the numbers of bacteria associated with periodontal disease, such as Porphyromonas gingivalis and Fusobacterium nucleatum. Clinical trials have shown that ATRIDOX is superior to vehicle control and oral hygiene and meets the standard of being at least 75% as good as scaling and root planing (SRP), the standard treatment for periodontitis[5].

Financial Performance

The financial performance of ATRIDOX is tied to the overall growth of the periodontal therapeutics market. As the market expands, driven by increasing demand and favorable market conditions, the revenue generated by ATRIDOX is expected to grow. The local antibiotics segment, which includes ATRIDOX, is anticipated to grow at a high revenue CAGR during the forecast period, contributing significantly to the overall market revenue[2].

Market Attractiveness

The market attractiveness of ATRIDOX is high due to its efficacy, safety profile, and the growing preference for local antibiotics over systemic treatments. The product's ability to offer site-specific therapy with reduced side effects enhances its market appeal. Additionally, the increasing awareness of periodontal health and the rising number of patients seeking effective treatments further boost its market attractiveness[2].

Future Outlook

The future outlook for ATRIDOX is promising, given the projected growth of the periodontal therapeutics market. As the global population ages and the prevalence of diabetes and periodontal diseases increases, the demand for effective treatments like ATRIDOX is expected to rise. Continuous innovation and adherence to regulatory standards will be crucial for maintaining its market position.

Key Takeaways

  • Market Growth: The periodontal therapeutics market, including ATRIDOX, is expected to grow at a CAGR of 8.3% to reach $4.5 billion by 2031.
  • Regional Dominance: North America, particularly the United States, holds the largest market share due to high prevalence and advanced healthcare infrastructure.
  • Distribution Channels: ATRIDOX is available through hospitals, retail pharmacies, drug stores, and e-commerce platforms.
  • Clinical Efficacy: ATRIDOX has demonstrated efficacy in reducing periodontal disease-associated bacteria and meets standards comparable to SRP.
  • Regulatory Challenges: The market faces regulatory challenges, but ATRIDOX has already secured necessary approvals.
  • Financial Performance: The revenue generated by ATRIDOX is expected to grow with the expanding market.

FAQs

Q: What is ATRIDOX used for? A: ATRIDOX is used to treat periodontitis, a chronic bacterial infection of the gums and bone supporting the teeth.

Q: How does ATRIDOX compare to other treatments? A: ATRIDOX has been shown to be superior to vehicle control and oral hygiene and meets the standard of being at least 75% as good as scaling and root planing (SRP)[5].

Q: What are the key factors driving the growth of the periodontal therapeutics market? A: The growth is driven by the increasing prevalence of periodontal diseases, rising cases of diabetes, and an aging global population[2].

Q: Which region dominates the market for periodontal therapeutics? A: North America, particularly the United States, holds the largest market share due to high prevalence and advanced healthcare infrastructure[2].

Q: What are the common distribution channels for ATRIDOX? A: ATRIDOX is available through hospitals, retail pharmacies, drug stores, and e-commerce platforms[1][4].

Cited Sources

  1. Biospace: Periodontal Therapeutics Market Share, Industry Growth, Trend ...
  2. Growth Plus Reports: Periodontal Therapeutics Market 2031 - $4.5 Billion Revenue Forecast
  3. Transparency Market Research: Periodontal Therapeutics Market Analysis Report 2027
  4. FDA: Atridox (doxycycline hyclate) periodontal label - accessdata.fda.gov

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