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Last Updated: December 22, 2024

ATROPINE (AUTOINJECTOR) Drug Patent Profile


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Which patents cover Atropine (autoinjector), and what generic alternatives are available?

Atropine (autoinjector) is a drug marketed by Rafa Labs Ltd and is included in one NDA.

The generic ingredient in ATROPINE (AUTOINJECTOR) is atropine. There are twenty-three drug master file entries for this compound. Two suppliers are listed for this compound. Additional details are available on the atropine profile page.

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Summary for ATROPINE (AUTOINJECTOR)
Drug patent expirations by year for ATROPINE (AUTOINJECTOR)
Recent Clinical Trials for ATROPINE (AUTOINJECTOR)

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
U.S. Army Space and Missile Defense CommandPhase 1
MicroDose Defense Products L.L.C.Phase 1
University of PittsburghPhase 1

See all ATROPINE (AUTOINJECTOR) clinical trials

Pharmacology for ATROPINE (AUTOINJECTOR)

US Patents and Regulatory Information for ATROPINE (AUTOINJECTOR)

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Rafa Labs Ltd ATROPINE (AUTOINJECTOR) atropine SOLUTION;INTRAMUSCULAR 212319-001 Jul 9, 2018 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

ATROPINE (AUTOINJECTOR) Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Atropine Autoinjectors

Introduction

Atropine autoinjectors, such as the ATROPEN, play a critical role in emergency medical treatments, particularly for organophosphorus or nerve agent poisonings, and other severe muscarinic effects. Here, we delve into the market dynamics and financial trajectory of atropine autoinjectors, highlighting key trends, drivers, and regional performances.

Market Overview

The global market for atropine sulfate injections, particularly in autoinjector form, is experiencing steady growth driven by several factors.

Global Growth Rate

The atropine sulfate injection market is projected to grow at a compound annual growth rate (CAGR) of 2.00% from 2023 to 2030[1].

Market Size and Forecast

While the specific market size for atropine autoinjectors is not isolated, the broader autoinjectors market provides context. The global autoinjectors market is expected to grow from $1.40 billion in 2024 to $3.02 billion by 2030, with a CAGR of 13.6%[3].

Regional Performance

North America

North America dominates the atropine sulfate injection market, holding a substantial 40% market share. This dominance is attributed to the region's advanced healthcare infrastructure, high incidence of diseases requiring atropine interventions, and robust research and development activities. The market size in North America is anticipated to reach significant figures by 2030, driven by the urgent need for atropine in emergencies and a well-established healthcare system[1].

Asia Pacific

The Asia Pacific region is the fastest-growing hub for atropine sulfate injections, projected to hold a 20% market share. This growth is fueled by increasing healthcare investments, rising awareness about atropine applications, and a growing population. The region's expanding healthcare infrastructure and advancements in medical treatments further support this trend[1].

Drivers of Market Growth

Technological Advancements

Advancements in autoinjector technology, such as improved design, connectivity features for data tracking, and dosage reminders, are significant drivers. These innovations enhance safety, ease of use, and patient compliance, contributing to the growing adoption of autoinjectors[3][4].

Increasing Prevalence of Chronic Diseases

The rising prevalence of chronic diseases like diabetes, anaphylaxis, and rheumatoid arthritis drives the demand for user-friendly medication delivery systems, including atropine autoinjectors[4].

Government Policies and Healthcare Expenditure

Supportive government policies, increased healthcare expenditure, and the need for rapid medication in emergencies further boost the market growth. In regions like North America and Europe, favorable regulatory and reimbursement policies enhance the adoption of autoinjectors[3][4].

Online Sales and Digital Platforms

The shift towards online sales is a notable trend in the atropine sulfate injection market. Online pharmacies offer convenience and accessibility, especially in regions with limited access to brick-and-mortar pharmacies. This trend is expected to grow as more consumers embrace the convenience of ordering pharmaceuticals online[1].

Military and Defense Applications

The Department of Defense (DOD) has awarded significant contracts for the development of advanced atropine autoinjectors, such as the Reconstitution Autoinjector Device – Atropine (RAD-A). This device, developed by Kaléo, Inc., is designed to treat nerve agent exposure and extends the shelf-life of the autoinjector, reducing the sustainment burden for the military[2].

Product Specifics and Usage

ATROPEN Autoinjector

The ATROPEN autoinjector is a single-dose device intended for the initial treatment of muscarinic symptoms of insecticide or nerve agent poisonings. It is available in various strengths and should be administered intramuscularly into the mid-lateral thigh. The dosage is dependent on the patient's weight and the severity of symptoms[5].

Dosage and Administration

For mild symptoms, one injection is administered, while severe symptoms require multiple injections in rapid succession. It is crucial to seek definitive medical care immediately after administration[5].

Safety and Precautions

Atropine autoinjectors come with several safety considerations, including cardiovascular risks, heat injury, acute glaucoma, and urinary retention. These risks necessitate cautious use, especially in patients with known cardiovascular disease or other specific health conditions[5].

Key Takeaways

  • Global Growth: The atropine sulfate injection market is expected to grow at a CAGR of 2.00% from 2023 to 2030.
  • Regional Dominance: North America holds a significant market share, while the Asia Pacific region is the fastest-growing hub.
  • Technological Advancements: Innovations in autoinjector technology drive market growth.
  • Chronic Diseases: Increasing prevalence of chronic diseases fuels demand for atropine autoinjectors.
  • Online Sales: The trend towards online sales is increasing due to convenience and accessibility.
  • Military Applications: Advanced atropine autoinjectors are being developed for military use.

FAQs

What is the primary use of atropine autoinjectors?

Atropine autoinjectors are primarily used for the temporary blocking of severe or life-threatening muscarinic effects, such as treating organophosphorus or muscarinic mushroom poisoning and bradyasystolic cardiac arrest.

Which region dominates the atropine sulfate injection market?

North America dominates the atropine sulfate injection market, holding a substantial 40% market share.

What are the key drivers of the atropine autoinjector market?

Key drivers include technological advancements, increasing prevalence of chronic diseases, supportive government policies, and the growing trend of online sales.

What is the RAD-A device, and why is it significant?

The RAD-A (Reconstitution Autoinjector Device – Atropine) is a novel wet/dry autoinjector device developed to treat nerve agent exposure. It extends the shelf-life of the autoinjector and reduces the sustainment burden for the military.

What are the safety precautions associated with atropine autoinjectors?

Atropine autoinjectors come with risks such as cardiovascular adverse reactions, heat injury, acute glaucoma, and urinary retention, necessitating cautious use, especially in patients with specific health conditions.

Sources

  1. Cognitive Market Research: Atropine Sulfate Injection Market Report 2024 (Global Edition)
  2. JPEO-CBRND: JPEO-CBRND Awards $39.8 Million Contract to Kaléo, Inc. for Next Generation Reconstitution Autoinjector Device – Atropine (RAD-A)
  3. MarketsandMarkets: Autoinjectors Market Growth, Drivers, and Opportunities
  4. Grand View Research: Auto-Injectors Market Size, Share, & Trends Report, 2030
  5. DailyMed: Label: ATROPEN AUTO-INJECTOR- atropine injection

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