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Last Updated: December 22, 2024

AZACTAM IN PLASTIC CONTAINER Drug Patent Profile


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Which patents cover Azactam In Plastic Container, and what generic alternatives are available?

Azactam In Plastic Container is a drug marketed by Bristol Myers Squibb and is included in one NDA.

The generic ingredient in AZACTAM IN PLASTIC CONTAINER is aztreonam. There are eight drug master file entries for this compound. Four suppliers are listed for this compound. Additional details are available on the aztreonam profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Azactam In Plastic Container

A generic version of AZACTAM IN PLASTIC CONTAINER was approved as aztreonam by FRESENIUS KABI USA on June 18th, 2010.

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Summary for AZACTAM IN PLASTIC CONTAINER
Drug patent expirations by year for AZACTAM IN PLASTIC CONTAINER
Recent Clinical Trials for AZACTAM IN PLASTIC CONTAINER

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
Eastern Virginia Medical SchoolPhase 2
Virginia Commonwealth UniversityPhase 2

See all AZACTAM IN PLASTIC CONTAINER clinical trials

US Patents and Regulatory Information for AZACTAM IN PLASTIC CONTAINER

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bristol Myers Squibb AZACTAM IN PLASTIC CONTAINER aztreonam INJECTABLE;INJECTION 050632-003 May 24, 1989 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Bristol Myers Squibb AZACTAM IN PLASTIC CONTAINER aztreonam INJECTABLE;INJECTION 050632-002 May 24, 1989 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Bristol Myers Squibb AZACTAM IN PLASTIC CONTAINER aztreonam INJECTABLE;INJECTION 050632-001 May 24, 1989 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for AZACTAM IN PLASTIC CONTAINER

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Gilead Sciences Ireland UC Cayston aztreonam EMEA/H/C/000996
Cayston is indicated for the suppressive therapy of chronic pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis (CF) aged 6 years and older.Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Authorised no no no 2009-09-21
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

AZACTAM IN PLASTIC CONTAINER Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory of Aztreonam (AZACTAM) in Plastic Containers

Introduction

Aztreonam, marketed as AZACTAM, is a synthetic beta-lactam antibiotic specifically designed to combat Gram-negative bacterial infections. Its unique monocyclic beta-lactam structure sets it apart from other antibiotics, making it resistant to certain bacterial enzymes. Here, we delve into the market dynamics and financial trajectory of Aztreonam, particularly in its plastic container formulation.

Market Size and Growth

The Aztreonam market has been experiencing significant growth, driven by several key factors. As of 2023, the market size was valued at USD 1.5 billion and is projected to reach USD 2.42 billion by 2031, growing at a CAGR of 6% during this period[1].

Drivers of Market Growth

Rising Antibiotic Resistance

One of the primary drivers of the Aztreonam market is the increasing incidence of antibiotic-resistant infections. As bacteria evolve and become resistant to existing antibiotics, the demand for effective treatments like Aztreonam increases[1].

Increasing Prevalence of Infectious Diseases

The global rise in infectious diseases, particularly those caused by resistant strains of bacteria, has further fueled the demand for Aztreonam. This trend is especially notable in hospital settings where the risk of nosocomial infections is high[1].

Advancements in Drug Development

Ongoing research and development in the pharmaceutical industry have led to innovative formulations and improved delivery methods for Aztreonam. Extended-release formulations, for instance, are being developed to enhance patient compliance and therapeutic outcomes[1].

Applications and Uses

Aztreonam is primarily used to treat infections caused by Gram-negative bacteria, including respiratory, urinary tract, and intra-abdominal infections. It is particularly effective against Pseudomonas aeruginosa and other resistant strains[1][3].

Unique Properties

The monocyclic beta-lactam structure of Aztreonam makes it resistant to certain bacterial enzymes that typically break down other beta-lactam antibiotics. This unique property enhances its effectiveness against resistant bacteria[1][3].

Market Segmentation

The Aztreonam market is segmented based on type, application, and geographical regions. Key segments include:

  • Type: 0.5g/Bottle, 1.0g/Bottle, 2.0g/Bottle[5].
  • Application: Hospital Pharmacy, Retail Pharmacy, Others[5].
  • Geographical Regions: North America, Europe, Asia-Pacific, South America, and Middle-East and Africa[5].

Financial Performance

Historically, Aztreonam has shown strong financial performance. For example, in the first quarter of 1996, sales of Azactam (aztreonam) doubled to $19.9 million despite losing patent protection, as no generic rivals had been approved at that time[2].

Investment Prospects

The Aztreonam market presents significant investment opportunities due to its pivotal role in combating resistant infections. Companies developing new formulations and delivery methods for Aztreonam are particularly attractive to investors. Strategic partnerships and mergers and acquisitions among pharmaceutical companies are also driving innovation and growth in the sector[1].

Strategic Developments

Pharmaceutical companies are forming strategic partnerships to advance Aztreonam research and development. These collaborations aim to leverage combined expertise and resources to bring innovative solutions to market faster. The market has witnessed several mergers and acquisitions as companies seek to strengthen their portfolios and expand their market presence[1].

Competitive Landscape

The competitive landscape of the Aztreonam market includes several key players such as Shanxi PUDE Pharmaceutical, Hunan Kelun Pharmaceutical, Hainan Lingkang Pharmaceutical, and others. These companies are actively involved in new product launches, collaborations, and mergers and acquisitions to maintain their market position[5].

Market Outlook

The Aztreonam market is expected to grow steadily due to the increasing demand for effective treatments against resistant infections and ongoing advancements in drug development. The market’s expansion presents significant investment opportunities, and investors should keep an eye on emerging trends and strategic developments in this dynamic market[1].

Challenges and Opportunities

While the market is poised for growth, it also faces challenges such as the need for continuous innovation to stay ahead of bacterial resistance. However, this challenge also presents an opportunity for companies to invest in research and development, leading to new and improved formulations of Aztreonam[1].

"Recent trends include the development of new formulations, strategic partnerships in research and development, and mergers and acquisitions among pharmaceutical companies to advance Aztreonam innovations."[1]

Key Takeaways

  • The Aztreonam market is valued at USD 1.5 billion as of 2023 and is expected to reach USD 2.42 billion by 2031.
  • The market is driven by rising antibiotic resistance, increasing prevalence of infectious diseases, and advancements in drug development.
  • Aztreonam is unique due to its monocyclic beta-lactam structure, making it effective against resistant bacteria.
  • The market is segmented by type, application, and geographical regions.
  • Significant investment opportunities exist due to the drug’s pivotal role in combating resistant infections.
  • Strategic partnerships and mergers and acquisitions are driving innovation and growth.

FAQs

What is Aztreonam used for?

Aztreonam is used to treat infections caused by Gram-negative bacteria, including respiratory, urinary tract, and intra-abdominal infections. It is particularly effective against Pseudomonas aeruginosa and other resistant strains[1][3].

What makes Aztreonam unique?

Aztreonam's unique monocyclic beta-lactam structure makes it resistant to certain bacterial enzymes that typically break down other beta-lactam antibiotics, enhancing its effectiveness against resistant bacteria[1][3].

What are the key drivers of the Aztreonam market?

The key drivers include the rising incidence of antibiotic-resistant infections, the increasing prevalence of infectious diseases, and advancements in drug development such as new formulations and delivery methods[1].

Who are the key players in the Aztreonam market?

Key players include Shanxi PUDE Pharmaceutical, Hunan Kelun Pharmaceutical, Hainan Lingkang Pharmaceutical, and others. These companies are actively involved in new product launches, collaborations, and mergers and acquisitions[5].

What is the projected market size of Aztreonam by 2031?

The Aztreonam market is expected to reach USD 2.42 billion by 2031, growing at a CAGR of 6% from 2023 to 2031[1].

How does Aztreonam contribute to the fight against antibiotic resistance?

Aztreonam is a crucial weapon in the fight against multi-drug-resistant strains and hospital-acquired infections due to its potency against resistant bacteria like Pseudomonas aeruginosa. Its unique structure and ongoing innovations in formulations and delivery methods make it an effective treatment option[1].

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