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Last Updated: December 22, 2024

BLENOXANE Drug Patent Profile


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Which patents cover Blenoxane, and when can generic versions of Blenoxane launch?

Blenoxane is a drug marketed by Bristol Myers Squibb and is included in one NDA.

The generic ingredient in BLENOXANE is bleomycin sulfate. There are six drug master file entries for this compound. Six suppliers are listed for this compound. Additional details are available on the bleomycin sulfate profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Blenoxane

A generic version of BLENOXANE was approved as bleomycin sulfate by HOSPIRA on March 10th, 2000.

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Summary for BLENOXANE
Drug patent expirations by year for BLENOXANE
Recent Clinical Trials for BLENOXANE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University of ArkansasPhase 1
National Cancer Institute (NCI)Phase 1
AIDS Malignancy ConsortiumPhase 1

See all BLENOXANE clinical trials

US Patents and Regulatory Information for BLENOXANE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bristol Myers Squibb BLENOXANE bleomycin sulfate INJECTABLE;INJECTION 050443-001 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Bristol Myers Squibb BLENOXANE bleomycin sulfate INJECTABLE;INJECTION 050443-002 Sep 7, 1995 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

BLENOXANE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for BLENOXANE

Overview of BLENOXANE

BLENOXANE, also known as bleomycin sulfate, is a glycopeptide antibiotic used in the treatment of various types of cancer, including squamous cell carcinoma, Hodgkin’s disease, non-Hodgkin’s lymphoma, and testicular carcinoma. It is particularly effective in managing cancers such as those of the head and neck, penis, cervix, and vulva[2][4].

Market Size and Growth

The cervical cancer drugs market, which includes BLENOXANE, has been experiencing steady growth. In 2023, the global cervical cancer drugs market size was valued at $24.25 billion and is expected to grow to $25.42 billion in 2024 at a compound annual growth rate (CAGR) of 4.8%. By 2028, the market is projected to reach $30.77 billion with a CAGR of 4.9%[1].

Segmentation and Distribution

By Cancer Type

BLENOXANE is used in treating various types of cancers, with squamous cell carcinoma and adenocarcinoma being significant segments within the cervical cancer market. The drug's efficacy in these cancer types contributes to its market share[1].

By Drug Type

BLENOXANE falls under the category of other drug types within the cervical cancer drugs market. Other drugs in this market include Avastin and Bevacizumab, but BLENOXANE remains a crucial option due to its specific indications and use cases[1].

By Distribution Channel

The distribution channels for BLENOXANE include hospitals pharmacies, retail pharmacies, and other distribution channels. Hospitals pharmacies are a major segment, given the need for administration under the supervision of a qualified physician experienced in cancer chemotherapeutic agents[1].

Regional Analysis

North America

North America was the largest region in the cervical cancer drugs market in 2023. This region is expected to continue its dominance due to factors such as advanced healthcare infrastructure, significant R&D expenditure, and favorable reimbursement policies[1].

Middle East

The Middle East is anticipated to be the fastest-growing region during the forecast period. This growth can be attributed to improving healthcare infrastructure and increasing awareness about advanced cancer treatments[1].

Financial Trajectory

Revenue Contribution

BLENOXANE, as part of the broader cervical cancer drugs market, contributes to the overall revenue. While specific financial figures for BLENOXANE are not provided, its inclusion in the market segmentation indicates its role in the market's growth.

Market Trends

The market is driven by several trends, including advancements in immunotherapy, precision medicine, targeted therapies, and expanded HPV vaccination programs. These trends are expected to continue driving the market forward, benefiting drugs like BLENOXANE that are part of these therapeutic advancements[1].

Competitive Landscape

Mergers and Acquisitions

The pharmaceutical industry, including the segment for cervical cancer drugs, has seen significant M&A activities. For example, GSK's acquisition of AffinivaxInc. in August 2022 highlights the industry's efforts to expand portfolios and technologies, which can impact the market dynamics for drugs like BLENOXANE[1].

Clinical and Therapeutic Use

Indications and Usage

BLENOXANE is indicated for the management of various neoplasms, including squamous cell carcinoma of the head and neck, penis, cervix, and vulva. It is also effective in treating malignant pleural effusion and certain types of lymphomas and testicular carcinomas[2].

Safety and Efficacy

The drug is known for its potential pulmonary toxicity, which is a significant consideration in its administration. Despite this, BLENOXANE has shown efficacy in clinical trials, particularly in reducing the recurrence rate of malignant pleural effusion compared to other treatments[2].

Future Outlook

The future outlook for BLENOXANE is tied to the overall growth of the cervical cancer drugs market. With advancements in immunotherapy, precision medicine, and targeted therapies, the demand for effective cancer treatments is expected to increase. As healthcare infrastructure develops, especially in regions like the Middle East, the market for drugs like BLENOXANE is likely to expand.

Key Takeaways

  • Market Growth: The cervical cancer drugs market, which includes BLENOXANE, is expected to grow from $24.25 billion in 2023 to $30.77 billion by 2028.
  • Regional Dominance: North America is the largest region, with the Middle East expected to be the fastest-growing.
  • Distribution Channels: Hospitals pharmacies are a major distribution channel for BLENOXANE.
  • Clinical Use: BLENOXANE is indicated for various types of cancers and malignant pleural effusion.
  • Safety Considerations: The drug is associated with pulmonary toxicity and other side effects.

FAQs

What is BLENOXANE used for?

BLENOXANE is used in the treatment of various types of cancer, including squamous cell carcinoma, Hodgkin’s disease, non-Hodgkin’s lymphoma, and testicular carcinoma. It is also effective in managing malignant pleural effusion[2].

What are the potential side effects of BLENOXANE?

BLENOXANE is associated with pulmonary toxicity, which can manifest as pneumonitis and occasionally progress to pulmonary fibrosis. Other side effects include skin toxicity, vascular complications, and local pain at the site of administration[2].

How is BLENOXANE administered?

BLENOXANE can be administered via intravenous, intramuscular, subcutaneous, and intrapleural routes. It is recommended to be administered under the supervision of a qualified physician experienced in cancer chemotherapeutic agents[2][4].

What is the market outlook for BLENOXANE?

The market outlook for BLENOXANE is positive, driven by the overall growth of the cervical cancer drugs market. Advancements in immunotherapy, precision medicine, and targeted therapies are expected to increase demand for effective cancer treatments like BLENOXANE[1].

Which regions are expected to drive the growth of the cervical cancer drugs market?

North America is currently the largest region, but the Middle East is expected to be the fastest-growing region during the forecast period due to improving healthcare infrastructure and increasing awareness about advanced cancer treatments[1].

Sources

  1. The Business Research Company, "Global Cervical Cancer Drugs Market Report 2024"
  2. FDA, "BLENOXANE - accessdata.fda.gov"
  3. BioSpace, "Antibody Drug Conjugates Market Size to Reach USD 28.61 Bn by 2033"
  4. Wikipedia, "Bleomycin"
  5. AACR Journals, "AACR Cancer Progress Report 2013"

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