You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: April 18, 2025

CLINDAMYCIN PHOSPHATE AND TRETINOIN Drug Patent Profile


✉ Email this page to a colleague

« Back to Dashboard


When do Clindamycin Phosphate And Tretinoin patents expire, and when can generic versions of Clindamycin Phosphate And Tretinoin launch?

Clindamycin Phosphate And Tretinoin is a drug marketed by Actavis Mid Atlantic, Encube, and Solaris Pharma Corp. and is included in three NDAs.

The generic ingredient in CLINDAMYCIN PHOSPHATE AND TRETINOIN is clindamycin phosphate; tretinoin. There are fifty-five drug master file entries for this compound. Six suppliers are listed for this compound. Additional details are available on the clindamycin phosphate; tretinoin profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Clindamycin Phosphate And Tretinoin

A generic version of CLINDAMYCIN PHOSPHATE AND TRETINOIN was approved as clindamycin phosphate; tretinoin by ACTAVIS MID ATLANTIC on June 12th, 2015.

  Try for Free

AI Research Assistant
Questions you can ask:
  • What is the 5 year forecast for CLINDAMYCIN PHOSPHATE AND TRETINOIN?
  • What are the global sales for CLINDAMYCIN PHOSPHATE AND TRETINOIN?
  • What is Average Wholesale Price for CLINDAMYCIN PHOSPHATE AND TRETINOIN?
Summary for CLINDAMYCIN PHOSPHATE AND TRETINOIN
Drug patent expirations by year for CLINDAMYCIN PHOSPHATE AND TRETINOIN
Recent Clinical Trials for CLINDAMYCIN PHOSPHATE AND TRETINOIN

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Haining Health-Coming Biotech Co., Ltd.Phase 2
Alphacait, LLCPhase 2
Zeichner, Joshua, M.D.Phase 4

See all CLINDAMYCIN PHOSPHATE AND TRETINOIN clinical trials

Pharmacology for CLINDAMYCIN PHOSPHATE AND TRETINOIN

US Patents and Regulatory Information for CLINDAMYCIN PHOSPHATE AND TRETINOIN

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Actavis Mid Atlantic CLINDAMYCIN PHOSPHATE AND TRETINOIN clindamycin phosphate; tretinoin GEL;TOPICAL 202564-001 Jun 12, 2015 AB1 RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Solaris Pharma Corp CLINDAMYCIN PHOSPHATE AND TRETINOIN clindamycin phosphate; tretinoin GEL;TOPICAL 212845-001 Feb 10, 2022 AB2 RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Encube CLINDAMYCIN PHOSPHATE AND TRETINOIN clindamycin phosphate; tretinoin GEL;TOPICAL 216943-001 Sep 1, 2023 AB2 RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 3 of 3 entries

Market Dynamics and Financial Trajectory for Clindamycin Phosphate and Tretinoin

Introduction

Clindamycin phosphate and tretinoin are two potent ingredients widely used in the treatment of various bacterial and dermatological conditions. This article delves into the market dynamics and financial trajectory of these drugs, highlighting key trends, regional performances, and future projections.

Global Market Size and Growth

The global market for clindamycin phosphate, particularly in its injectable and topical forms, is experiencing significant growth.

  • The clindamycin phosphate injection market was valued at USD 451.67 million in 2023 and is projected to grow to USD 743.86 million by 2032, exhibiting a CAGR of 5.7% during the forecast period[1].
  • The clindamycin phosphate topical market is expected to grow from $0.94 billion in 2023 to $1.86 billion by 2028, with a CAGR of 14.8%[3].

Regional Performance

North America

North America leads the clindamycin phosphate injection market due to its sophisticated healthcare system, high incidence of bacterial infections, and the presence of major pharmaceutical companies. The region's well-established healthcare infrastructure and significant investments in R&D have facilitated the widespread use of clindamycin phosphate injections, especially in hospital settings[1].

Europe

Europe is another significant market, driven by the increasing incidence of bacterial infections and a robust healthcare infrastructure. Countries like Germany, the UK, and France support the widespread use of clindamycin phosphate injections in both hospitals and clinics. The region's strong regulatory framework also encourages the adoption of effective antibiotics to combat resistant bacterial strains[1].

Asia Pacific

The Asia Pacific region is experiencing rapid growth, fueled by the increasing prevalence of bacterial infections and expanding healthcare infrastructure in emerging economies such as China, India, and Southeast Asian countries. This region is expected to witness substantial growth due to rising population, improving access to healthcare services, and growing awareness of antibiotic resistance[1].

Market Trends

Rising Antibiotic Resistance

The increasing prevalence of antibiotic-resistant bacteria is a key driver for the demand of effective treatments like clindamycin phosphate. This trend is particularly significant in regions where antibiotic resistance is on the rise, such as the U.S. and Canada[1].

Expansion in Emerging Markets

Growing healthcare infrastructure and rising incidence of bacterial infections in emerging markets are fueling market growth. Governments and healthcare organizations in these regions are prioritizing the availability of essential antibiotics, including clindamycin phosphate[1].

Development of Combination Therapies

Research into combination therapies involving clindamycin phosphate with other antibiotics is on the rise to enhance efficacy and combat complex infections. For example, the combination of clindamycin phosphate and tretinoin has shown significant efficacy in treating moderate to severe acne vulgaris[2].

Shift Towards Homecare Settings

There is a growing trend towards outpatient and homecare settings for administering antibiotics, supported by advancements in portable infusion technology. This shift is expected to further drive the demand for clindamycin phosphate injections[1].

Financial Trajectory

Clindamycin Phosphate Injection Market

  • The market is projected to grow from USD 476.69 million in 2024 to USD 743.86 million by 2032, with a CAGR of 5.7%[1].

Clindamycin Phosphate Topical Market

  • This market will grow from $0.94 billion in 2023 to $1.07 billion in 2024 and further to $1.86 billion by 2028, with a CAGR of 14.8%[3].

Strategic Initiatives

Companies in the clindamycin phosphate market are focusing on several strategic initiatives to drive growth:

  • Expanding product portfolios and enhancing distribution networks to reach diverse healthcare settings.
  • Forming strategic partnerships and acquisitions to access new markets and strengthen competitive positions.
  • Investing in R&D to innovate and improve product formulations, addressing emerging antibiotic resistance issues.
  • Targeted marketing efforts in emerging economies, robust pricing strategies, and enhanced customer engagement[1].

Tretinoin Market Dynamics

The global tretinoin market, often used in combination with clindamycin phosphate, is also seeing significant growth.

  • North America and Europe are the largest markets for tretinoin, with the U.S. having a high proportion of the population suffering from acne vulgaris[4].

Combination Therapies: Clindamycin Phosphate and Tretinoin

The combination of clindamycin phosphate and tretinoin has been shown to be highly effective in treating moderate to severe acne vulgaris. This combination enhances the comedolytic efficacy of tretinoin while maintaining its anti-inflammatory efficacy, accelerating the resolution of all types of acne lesions without affecting safety[2].

"The addition of clindamycin to tretinoin, as in CTG, enhances the comedolytic efficacy of tretinoin in moderate to severe acne of the face, maintaining at the same time its anti-inflammatory efficacy thus accelerating resolution of all types of acne lesions without affecting the safety of response to both components."[2]

Key Takeaways

  • The clindamycin phosphate market is driven by rising antibiotic resistance, expansion in emerging markets, and the development of combination therapies.
  • The Asia Pacific region is expected to witness substantial growth due to expanding healthcare access and rising infection rates.
  • Strategic initiatives such as product portfolio expansion, partnerships, and R&D investments are crucial for market growth.
  • The combination of clindamycin phosphate and tretinoin is highly effective in treating acne vulgaris.

FAQs

1. What is the projected growth rate of the clindamycin phosphate injection market?

The clindamycin phosphate injection market is projected to grow at a CAGR of 5.7% from 2023 to 2032[1].

2. Which region leads the clindamycin phosphate injection market?

North America leads the clindamycin phosphate injection market due to its sophisticated healthcare system and high incidence of bacterial infections[1].

3. What are the key drivers for the clindamycin phosphate topical market?

The key drivers include rising cases of bacterial skin infections, increasing antibiotic resistance, growing awareness of skin health, and expanding healthcare infrastructure in emerging economies[3].

4. How effective is the combination of clindamycin phosphate and tretinoin in treating acne?

The combination is highly effective, enhancing the comedolytic efficacy of tretinoin while maintaining its anti-inflammatory efficacy, thus accelerating the resolution of all types of acne lesions[2].

5. What are the strategic initiatives companies are taking to drive growth in the clindamycin phosphate market?

Companies are focusing on expanding product portfolios, enhancing distribution networks, forming strategic partnerships, investing in R&D, and implementing targeted marketing efforts[1].

Sources

  1. Polaris Market Research: Clindamycin Phosphate Injection Market Growth Report, 2032.
  2. PubMed: Efficacy of the fixed 1.2% clindamycin phosphate, 0.025% tretinoin.
  3. The Business Research Company: Clindamycin Phosphate Topical Global Market Report 2024.
  4. Fortune Business Insights: Tretinoin Market Size, Industry Share | Forecast 2032.
  5. Drug Patent Watch: Generic CLINDAMYCIN PHOSPHATE INN equivalents.

More… ↓

⤷  Try for Free

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.