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Last Updated: April 6, 2025

DELTA-CORTEF Drug Patent Profile


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When do Delta-cortef patents expire, and when can generic versions of Delta-cortef launch?

Delta-cortef is a drug marketed by Pharmacia And Upjohn and is included in one NDA.

The generic ingredient in DELTA-CORTEF is prednisolone. There are eighty-eight drug master file entries for this compound. Ten suppliers are listed for this compound. Additional details are available on the prednisolone profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Delta-cortef

A generic version of DELTA-CORTEF was approved as prednisolone by ZHEJIANG XIANJU on May 2nd, 2024.

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Summary for DELTA-CORTEF
Drug patent expirations by year for DELTA-CORTEF
Recent Clinical Trials for DELTA-CORTEF

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University of North Carolina, Chapel HillPhase 4
University Medical Center GroningenEarly Phase 1
Beth Israel Deaconess Medical CenterPhase 2

See all DELTA-CORTEF clinical trials

US Patents and Regulatory Information for DELTA-CORTEF

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Pharmacia And Upjohn DELTA-CORTEF prednisolone TABLET;ORAL 009987-004 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 1 of 1 entries

EU/EMA Drug Approvals for DELTA-CORTEF

CompanyDrugnameInnProduct Number / IndicationStatusGenericBiosimilarOrphanMarketing AuthorisationMarketing Refusal
LE VET B.V. Equisolon Prednisolone EMEA/V/C/002382
Alleviation of inflammatory and clinical parameters associated with recurrent airway obstruction (RAO) in horses, in combination with environmental control.
Authorised no no no 2014-03-12
>Company>Drugname>Inn>Product Number / Indication>Status>Generic>Biosimilar>Orphan>Marketing Authorisation>Marketing Refusal
Showing 1 to 1 of 1 entries

Market Dynamics and Financial Trajectory for Delta-Cortef

Introduction

Delta-Cortef, a brand name for the corticosteroid prednisolone, is a widely used medication for various inflammatory and immune system disorders. Understanding its market dynamics and financial trajectory involves analyzing its usage, competition, and the broader pharmaceutical market trends.

Therapeutic Uses and Demand

Delta-Cortef is used to treat a range of conditions, including arthritis, asthma, and severe allergic reactions. Its versatility and effectiveness contribute to its steady demand in the healthcare market[4].

Market Segmentation

The demand for Delta-Cortef can be segmented into several key areas:

  • Chronic Conditions: Arthritis, asthma, and autoimmune diseases.
  • Acute Conditions: Severe allergic reactions and certain infections.
  • COVID-19 Treatment: Although not recommended for mild-to-moderate cases, corticosteroids like prednisolone are crucial in treating severe COVID-19, particularly in hospitalized patients[5].

Competitive Landscape

The corticosteroid market is competitive, with several other glucocorticoids available, such as dexamethasone and methylprednisolone. However, Delta-Cortef remains a significant player due to its established brand and broad therapeutic applications.

Generic Competition

Prednisolone, the active ingredient in Delta-Cortef, is available in generic forms, which can impact the brand's market share. Generic versions often offer a cost-effective alternative, which can be attractive to patients and healthcare providers[1][4].

Financial Performance

The financial performance of Delta-Cortef is influenced by several factors, including sales volume, pricing strategies, and competition from generic alternatives.

Revenue Trends

While specific financial data for Delta-Cortef is not readily available, the overall market for corticosteroids is substantial. The revenue generated from corticosteroids is significant, driven by their widespread use in various medical conditions.

Pricing Strategies

The pricing of Delta-Cortef can vary based on the region, insurance coverage, and competition from generics. Pharmaceutical companies often adjust pricing to balance profitability with market demand and regulatory pressures.

Regulatory Environment

Regulatory guidelines and recommendations play a crucial role in the market dynamics of Delta-Cortef.

Guidelines and Recommendations

For instance, the Infectious Diseases Society of America (IDSA) guidelines recommend against the use of systemic corticosteroids in mild-to-moderate COVID-19 but strongly recommend them for severe and critical cases. Such guidelines can significantly impact the demand for Delta-Cortef[5].

Side Effects and Safety Concerns

The side effect profile of Delta-Cortef, including common side effects like fluid retention, increased blood pressure, and behavioral changes, can influence patient and prescriber preferences[1].

Impact on Market Perception

While side effects are a concern, the therapeutic benefits of Delta-Cortef often outweigh these risks, especially in severe conditions. However, the presence of side effects can lead to a cautious approach by some prescribers and patients.

Innovation and R&D

Continuous innovation and research in the pharmaceutical sector can impact the market trajectory of Delta-Cortef.

New Therapeutic Areas

Research into new therapeutic areas, such as the use of corticosteroids in sepsis and COVID-19, can expand the market for Delta-Cortef. For example, studies on the combined use of hydrocortisone with other treatments in septic shock highlight the ongoing relevance of corticosteroids in critical care[2].

Market Trends and Projections

The pharmaceutical market is dynamic, with trends influenced by technological advancements, regulatory changes, and shifting healthcare needs.

Growing Demand for Corticosteroids

The increasing prevalence of chronic diseases and the ongoing need for effective treatments in acute conditions ensure a steady demand for corticosteroids like Delta-Cortef.

Impact of COVID-19

The COVID-19 pandemic has highlighted the critical role of corticosteroids in treating severe cases, which has temporarily boosted demand. However, long-term market trends will depend on broader healthcare needs and the availability of alternative treatments[5].

Key Takeaways

  • Steady Demand: Delta-Cortef benefits from its broad therapeutic applications and established brand.
  • Competitive Landscape: The market is competitive, with generic alternatives and other glucocorticoids.
  • Regulatory Influence: Guidelines and recommendations significantly impact the use and demand for Delta-Cortef.
  • Innovation: Ongoing research into new therapeutic areas can expand the market for Delta-Cortef.
  • Financial Performance: Revenue trends are influenced by sales volume, pricing, and competition.

FAQs

Q: What are the common side effects of Delta-Cortef?

A: Common side effects include fluid retention, increased blood pressure, behavioral changes, and mood changes[1].

Q: How is Delta-Cortef used in treating COVID-19?

A: Delta-Cortef, or prednisolone, is recommended for severe and critical COVID-19 cases but not for mild-to-moderate cases due to potential increased mortality risk[5].

Q: What is the competitive landscape for Delta-Cortef?

A: The market is competitive with other glucocorticoids like dexamethasone and methylprednisolone, as well as generic versions of prednisolone[1][4].

Q: How does the regulatory environment impact Delta-Cortef?

A: Regulatory guidelines, such as those from IDSA, influence the use and demand for Delta-Cortef, particularly in the context of COVID-19 treatment[5].

Q: What are the potential long-term financial projections for Delta-Cortef?

A: Long-term financial projections depend on broader healthcare needs, the availability of alternative treatments, and ongoing research into new therapeutic areas.

Cited Sources:

  1. Drugs.com - Delta-Cortef Side Effects: Common, Severe, Long Term.
  2. MDPI - Recent Data about the Use of Corticosteroids in Sepsis—Review of Current Evidence.
  3. Exelixis - Second Quarter 2020 Financial Results.
  4. WebMD - Delta-Cortef Tablet - Uses, Side Effects, and More.
  5. IDSA - Guidelines on the Treatment and Management of Patients with COVID-19.

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