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Last Updated: December 22, 2024

DEMEROL Drug Patent Profile


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Which patents cover Demerol, and what generic alternatives are available?

Demerol is a drug marketed by Hospira and Quagen and is included in two NDAs.

The generic ingredient in DEMEROL is meperidine hydrochloride. There are six drug master file entries for this compound. Five suppliers are listed for this compound. Additional details are available on the meperidine hydrochloride profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Demerol

A generic version of DEMEROL was approved as meperidine hydrochloride by HIKMA on January 30th, 1985.

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Summary for DEMEROL
Drug patent expirations by year for DEMEROL
Drug Prices for DEMEROL

See drug prices for DEMEROL

Recent Clinical Trials for DEMEROL

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Centre hospitalier de l'Université de Montréal (CHUM)Phase 3
Monica BhatiaPhase 1
Ufuk UniversityPhase 4

See all DEMEROL clinical trials

Pharmacology for DEMEROL
Drug ClassOpioid Agonist
Mechanism of ActionFull Opioid Agonists

US Patents and Regulatory Information for DEMEROL

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Hospira DEMEROL meperidine hydrochloride INJECTABLE;INJECTION 021171-001 Approved Prior to Jan 1, 1982 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Quagen DEMEROL meperidine hydrochloride INJECTABLE;INJECTION 005010-009 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Hospira DEMEROL meperidine hydrochloride INJECTABLE;INJECTION 021171-004 Approved Prior to Jan 1, 1982 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

DEMEROL Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Demerol (Meperidine)

Introduction

Demerol, also known as meperidine, is a synthetic opioid analgesic that has been a staple in pain management for several decades. Understanding the market dynamics and financial trajectory of Demerol is crucial for pharmaceutical companies, investors, and healthcare professionals.

Global Market Size and Forecast

The global meperidine (Demerol) market is valued at approximately US$ 493.4 million in 2023 and is projected to grow at a Compound Annual Growth Rate (CAGR) of 1.5% from 2023 to 2030[1].

Drivers of Market Growth

Several factors are driving the growth of the Demerol market:

Increasing Surgical Procedures

The rise in surgical procedures, including caesarean sections and hysterectomies, contributes significantly to the demand for Demerol. For instance, the increasing number of caesarean sections globally, with over 21% of all childbirths being caesarean sections, boosts the use of Demerol as a painkiller[1].

Prevalence of Chronic Pain and Diseases

The increasing prevalence of diseases that cause chronic pain, such as cancer, arthritis, and fibromyalgia, is a key driver. Around 75% of patients who undergo surgery experience acute postoperative pain, further bolstering the demand for Demerol[4].

Facility Expansion and Geographical Reach

Pharmaceutical companies are expanding their facilities and geographical reach, which helps in increasing the customer base and driving market growth. For example, Sun Pharmaceutical Industries Ltd. and Pfizer Inc. have announced significant expansion plans to boost their market presence[1].

Regional Analysis

North America

North America holds the dominant position in the global Demerol market, primarily due to the high number of surgical procedures, such as hysterectomies, in the U.S. The region's large market share is also attributed to the increasing incidence of pain and pain-related disorders[1][4].

Asia Pacific

The Asia Pacific region is expected to witness the fastest growth over the forecast period. This growth is driven by the increasing volume of dental and cosmetic surgeries, advancements in surgical procedures, and the growing use of Demerol in post-operative pain management. The expanding geriatric population in this region also contributes to the rising demand for Demerol[4].

Market Segmentation

The global Demerol market is segmented based on distribution channels, including hospital pharmacies, retail pharmacies, and online pharmacies. Retail pharmacies are expected to dominate the market due to the increasing visits of patients to these pharmacies for medication purchases[1].

Key Players

Major players operating in the global Demerol market include Pfizer Inc., Hikma Pharmaceuticals USA Inc., Epic Pharma, Inc., Vintage Pharmaceuticals, Inc., Sanofi, Janssen Pharmaceuticals, Boehringer Ingelheim, Sun Pharmaceutical, Egalet Corporation, and Mallinckrodt Pharmaceuticals[1].

Financial Performance and R&D Spending

The pharmaceutical industry, including the segment for Demerol, has seen significant financial growth. Pharmaceutical and biotechnology sales revenue increased from $534 billion to $775 billion between 2006 and 2015. About 67% of drug companies saw an increase in their annual average profit margins during this period, with some companies achieving profit margins of up to 20%[2].

Research and development (R&D) spending has also been on the rise, increasing from $82 billion in 2008 to $89 billion in 2014. However, the impact of mergers and acquisitions on R&D spending and innovation is complex and can have varied effects[2].

Challenges and Restraints

Despite the growth drivers, the Demerol market faces several challenges:

Side Effects and Alternatives

The use of Demerol has been declining in some areas due to its side effects and the availability of alternative analgesics. For example, the average monthly usage of Demerol decreased significantly from 2018 to 2021, while the usage of alternatives like nalbuphine increased[1].

Regulatory and Market Pressures

Market pressures, including rising R&D costs, fewer drugs in development, and competition from generic drugs, pose significant challenges. These pressures have driven structural changes in the industry, such as increased use of acquisitions to access new research[2].

Historical Context and Pharmacology

Demerol was synthesized in 1939 by Eisleb and Schaumann and was initially seen as a synthetic alternative to morphine due to its spasmolytic properties. Its pharmacology and clinical uses have been well-documented, with it being used for various types of pain management[5].

Key Takeaways

  • The global Demerol market is valued at US$ 493.4 million in 2023 and is expected to grow at a CAGR of 1.5% from 2023 to 2030.
  • Increasing surgical procedures and the prevalence of chronic pain are key drivers of market growth.
  • North America dominates the market, while the Asia Pacific region is expected to witness the fastest growth.
  • Major pharmaceutical companies are expanding their facilities and geographical reach to boost market presence.
  • The market faces challenges from side effects, alternative analgesics, and regulatory pressures.

FAQs

What is the current market size of the global Demerol market?

The global Demerol market is valued at approximately US$ 493.4 million in 2023[1].

What is the expected CAGR of the global Demerol market from 2023 to 2030?

The global Demerol market is expected to grow at a CAGR of 1.5% from 2023 to 2030[1].

Which region holds the dominant position in the global Demerol market?

North America holds the dominant position in the global Demerol market[1][4].

What are the key drivers of the Demerol market growth?

Key drivers include increasing surgical procedures, prevalence of chronic pain, and facility expansion by pharmaceutical companies[1][4].

Who are the major players in the global Demerol market?

Major players include Pfizer Inc., Hikma Pharmaceuticals USA Inc., Epic Pharma, Inc., and others[1].

What are the challenges faced by the Demerol market?

Challenges include side effects, competition from alternative analgesics, and regulatory and market pressures[1][2].

Sources

  1. Coherent Market Insights: Meperidine (Demerol) Market Size, Trends and Forecast to 2030.
  2. GAO: Drug Industry: Profits, Research and Development Spending.
  3. Australian Institute of Criminology: Fentanyl availability on darknet markets.
  4. Mordor Intelligence: Meperidine Drugs Market Size & Share Analysis - Growth Trends.
  5. JAMA Network: DEMEROL—A NEW SYNTHETIC ANALGESIC: A REVIEW OF ITS PRESENT STATUS AND COMPARISON WITH MORPHINE.

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