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Last Updated: December 22, 2024

DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER Drug Patent Profile


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When do Dextrose 5% And Sodium Chloride 0.9% In Plastic Container patents expire, and when can generic versions of Dextrose 5% And Sodium Chloride 0.9% In Plastic Container launch?

Dextrose 5% And Sodium Chloride 0.9% In Plastic Container is a drug marketed by Abbott, B Braun, Icu Medical Inc, and Miles. and is included in five NDAs.

The generic ingredient in DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER is dextrose; sodium chloride. There are nine drug master file entries for this compound. Four suppliers are listed for this compound. Additional details are available on the dextrose; sodium chloride profile page.

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Summary for DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
Drug patent expirations by year for DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
Pharmacology for DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER

US Patents and Regulatory Information for DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Abbott DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER dextrose; sodium chloride INJECTABLE;INJECTION 019483-001 Oct 4, 1985 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Icu Medical Inc DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER dextrose; sodium chloride INJECTABLE;INJECTION 017585-001 Approved Prior to Jan 1, 1982 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
B Braun DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER dextrose; sodium chloride INJECTABLE;INJECTION 018026-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
B Braun DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER dextrose; sodium chloride INJECTABLE;INJECTION 019631-010 Feb 24, 1988 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Miles DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER dextrose; sodium chloride INJECTABLE;INJECTION 018500-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

DEXTROSE 5% AND SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Dextrose 5% and Sodium Chloride 0.9% in Plastic Containers

Introduction

Dextrose 5% and Sodium Chloride 0.9% solutions are widely used in medical settings as a source of water, electrolytes, and calories. These solutions are crucial for patient hydration, electrolyte balance, and nutritional support. Here, we delve into the market dynamics and financial trajectory of this essential medical product.

Market Size and Growth

The U.S. intravenous solutions market, which includes Dextrose 5% and Sodium Chloride 0.9% solutions, is substantial and growing. As of 2023, the market is valued at US$ 3,171.1 million and is expected to exhibit a Compound Annual Growth Rate (CAGR) of 7.2% from 2023 to 2030[1].

Key Players

Major companies such as Baxter International Inc., ICU Medical, Inc., Braun Melsungen Ag, and Grifols, S.A. dominate the market. These companies are continuously involved in research and development to improve the safety and efficacy of their products[1].

Solution Type and Market Share

Dextrose 5% and Sodium Chloride 0.9% solutions are among the most commonly used intravenous solutions. The market share of these solutions is significant, with various concentrations and formulations available to meet different clinical needs[1].

Uses and Indications

Dextrose 5% and Sodium Chloride 0.9% Injection, USP, is indicated as a source of water, electrolytes, and calories. It is used for rehydration, to provide free water and electrolytes, and as a vehicle for administering drugs[5].

Composition and Specifications

The solution typically contains 5% dextrose and 0.9% sodium chloride in water for injection. It is available in various container sizes, such as 250 mL, 500 mL, and 1000 mL, and is packaged in flexible PVC/DEHP containers with a shelf life of 24 months[2].

Stability and Storage

Studies have shown that Dextrose 5% and Sodium Chloride 0.9% solutions are chemically and physically stable when stored in appropriate containers. For instance, cyclosporine solutions diluted with 0.9% sodium chloride or 5% dextrose and stored in polypropylene-polyolefin bags remain stable for at least 14 days[3].

Market Drivers

Several factors drive the growth of the intravenous solutions market, including:

  • Increasing Research and Development: Continuous innovation by key players to provide safer and more effective treatment options[1].
  • Growing Demand for IV Fluids: The need for hydration and electrolyte balance in various medical conditions drives the demand for these solutions.
  • Aging Population and Chronic Diseases: An increasing elderly population and the prevalence of chronic diseases contribute to the higher demand for intravenous solutions.

Impact of COVID-19

The COVID-19 pandemic has significantly impacted the intravenous solutions market. Workforce and production challenges led to shortages of small- and large-volume intravenous solutions, including Dextrose 5% and Sodium Chloride 0.9% solutions. This shortage has necessitated alternative strategies for management and conservation[4].

Challenges and Restraints

Despite the growing demand, the market faces several challenges:

  • Supply Chain Disruptions: Shortages due to COVID-19 and other production challenges have affected the availability of these solutions.
  • Regulatory Compliance: Manufacturers must adhere to stringent regulatory requirements, which can be time-consuming and costly.
  • Competition: The market is highly competitive, with multiple players vying for market share.

Financial Trajectory

The financial trajectory of the intravenous solutions market, including Dextrose 5% and Sodium Chloride 0.9% solutions, is positive. With a projected CAGR of 7.2% from 2023 to 2030, the market is expected to reach a significant value by the end of the forecast period. This growth is driven by increasing demand, technological advancements, and the expanding healthcare sector[1].

Competitive Landscape

The competitive landscape is characterized by a few dominant players who invest heavily in research and development. For example, a study by Intermountain Healthcare showed that patients given lactated Ringer solution had a lower risk of kidney injury and death compared to those given saline, highlighting the importance of continuous innovation[1].

Product Innovations

Companies are focusing on improving the safety and efficacy of their products. For instance, the use of flexible PVC/DEHP containers and the development of solutions with different concentrations of dextrose and sodium chloride cater to various clinical needs[2].

Regulatory Environment

The regulatory environment plays a crucial role in the intravenous solutions market. Manufacturers must comply with FDA regulations and other international standards to ensure the safety and quality of their products.

Consumer Behavior and Preferences

Healthcare providers and patients prefer solutions that are safe, effective, and easy to administer. The preference for flexible containers and ready-to-use solutions is increasing due to their convenience and reduced risk of contamination.

Geographical Analysis

The U.S. market is a significant segment of the global intravenous solutions market. The demand for Dextrose 5% and Sodium Chloride 0.9% solutions is high in this region due to the large healthcare sector and the presence of major market players.

Future Outlook

The future outlook for Dextrose 5% and Sodium Chloride 0.9% solutions is promising. With the growing demand for intravenous fluids, advancements in technology, and the need for safer and more effective treatment options, the market is expected to continue its upward trajectory.

Key Takeaways

  • The U.S. intravenous solutions market, including Dextrose 5% and Sodium Chloride 0.9% solutions, is valued at US$ 3,171.1 million in 2023 and is expected to grow at a CAGR of 7.2% until 2030.
  • Key players such as Baxter International Inc., ICU Medical, Inc., Braun Melsungen Ag, and Grifols, S.A. dominate the market.
  • The solutions are used for rehydration, electrolyte balance, and as a vehicle for administering drugs.
  • The market faces challenges such as supply chain disruptions and regulatory compliance.
  • Continuous innovation and adherence to regulatory standards are crucial for market growth.

FAQs

What is the primary use of Dextrose 5% and Sodium Chloride 0.9% solutions?

Dextrose 5% and Sodium Chloride 0.9% solutions are primarily used as a source of water, electrolytes, and calories for patient hydration and electrolyte balance.

Which companies are major players in the intravenous solutions market?

Major players include Baxter International Inc., ICU Medical, Inc., Braun Melsungen Ag, and Grifols, S.A.

How has the COVID-19 pandemic affected the intravenous solutions market?

The COVID-19 pandemic has led to shortages of intravenous solutions due to workforce and production challenges, necessitating alternative management and conservation strategies.

What are the key drivers of the intravenous solutions market?

Key drivers include increasing research and development, growing demand for IV fluids, and an aging population with chronic diseases.

What is the expected growth rate of the U.S. intravenous solutions market?

The U.S. intravenous solutions market is expected to exhibit a CAGR of 7.2% from 2023 to 2030.

Sources

  1. Coherent Market Insights - U.S. Intravenous Solutions Market Size & Share Analysis
  2. ICU Medical - 5% Dextrose and 0.9% Sodium Chloride Injection, USP
  3. PubMed - Stability of cyclosporine solutions stored in polypropylene-polyolefin containers
  4. ASHP - Fluid Shortages - Suggestions for Management and Conservation
  5. RxList - Dextrose 5% in 0.9% Sodium Chloride

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