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Last Updated: December 22, 2024

GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE Drug Patent Profile


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When do Guaifenesin And Dextromethorphan Hydrobromide patents expire, and when can generic versions of Guaifenesin And Dextromethorphan Hydrobromide launch?

Guaifenesin And Dextromethorphan Hydrobromide is a drug marketed by Actavis Labs Fl, Amneal Pharms, Aurobindo Pharma, Dr Reddys, Perrigo R And D, and Sun Pharm. and is included in six NDAs.

The generic ingredient in GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE is dextromethorphan hydrobromide; guaifenesin. There are twenty-three drug master file entries for this compound. Sixty-three suppliers are listed for this compound. Additional details are available on the dextromethorphan hydrobromide; guaifenesin profile page.

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Summary for GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE
US Patents:0
Applicants:6
NDAs:6
Finished Product Suppliers / Packagers: 59
What excipients (inactive ingredients) are in GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE?GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE excipients list
DailyMed Link:GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE at DailyMed
Drug patent expirations by year for GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE

US Patents and Regulatory Information for GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Actavis Labs Fl GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE dextromethorphan hydrobromide; guaifenesin TABLET, EXTENDED RELEASE;ORAL 091070-001 Aug 31, 2015 OTC No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Dr Reddys GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE dextromethorphan hydrobromide; guaifenesin TABLET, EXTENDED RELEASE;ORAL 217340-001 Aug 1, 2023 OTC No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Amneal Pharms GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE dextromethorphan hydrobromide; guaifenesin TABLET, EXTENDED RELEASE;ORAL 209692-002 Nov 1, 2018 OTC No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Sun Pharm GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE dextromethorphan hydrobromide; guaifenesin TABLET, EXTENDED RELEASE;ORAL 214781-002 Jul 1, 2021 OTC No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Guaifenesin and Dextromethorphan Hydrobromide

Market Overview

Guaifenesin and dextromethorphan hydrobromide, commonly found in medications like Mucinex DM, are key components in the treatment of respiratory conditions such as coughs, chest congestion, and mucus buildup. Here’s a detailed look at the market dynamics and financial trajectory of this combination.

Global Market Size and Growth

The global guaifenesin market is projected to experience significant growth over the coming years. By 2027, the market is expected to reach approximately USD 95 million, growing at a CAGR of around 3.1% from 2022 to 2027[1].

However, a more expansive forecast suggests that the global guaifenesin market could be worth around US$ 2.7 billion by 2033, starting from US$ 1.3 billion in 2023, with a CAGR of 7.4% during the forecast period from 2024 to 2033[3].

Key Drivers

Increasing Prevalence of Respiratory Conditions

The growing prevalence of respiratory conditions such as chronic obstructive pulmonary disease (COPD), asthma, and acute respiratory infections is a major driver for the guaifenesin market. For instance, COPD affected approximately 251 million individuals globally in 2022, and asthma prevalence in the United States remains significant, affecting about 25 million people[3].

Pharmaceutical Sector Development

Advancements in the pharmaceutical sector and the development of innovative drug technologies are expected to offer significant growth opportunities. The combination of guaifenesin with other medications like dextromethorphan is particularly effective in treating cough and chest congestion, making it a preferred choice in hospitals and clinics[1].

COVID-19 Impact

The COVID-19 pandemic had a mixed impact on the market. Initially, it caused disruptions in production and supply chains, affecting the availability of medications. However, the surge in demand for cough and cold medications during the recovery phase led to major growth opportunities. The heightened awareness of respiratory health due to the pandemic also contributed to increased demand for over-the-counter expectorants like guaifenesin[1].

Regional Analysis

North America

North America is the fastest-growing region in the global guaifenesin market, expected to grow with a CAGR of around 4.5% during the forecast period. This region dominates the market due to the high demand for guaifenesin in treating acute rhinosinusitis, chest congestion, and coughing issues. The development in medical infrastructure and the growing demand for pharmaceutical drugs across various patient groups also contribute to this growth[1].

Other Regions

While North America leads, other regions such as Asia Pacific are also expected to see significant growth. The increasing incidence of respiratory conditions and the expanding healthcare infrastructure in these regions drive the demand for guaifenesin and its combinations[3].

Product Type and Distribution

Product Type

The market for guaifenesin is segmented into various product types, including tablets, granules, syrups, and others. Tablets are the leading segment, holding a market share of 42.7% in 2023. The combination of guaifenesin with dextromethorphan in extended-release tablets is particularly popular due to its efficacy in controlling cough and thinning mucus[3].

Distribution Channel

The distribution channel segment is dominated by hospital pharmacies, which hold the largest revenue share of 46.5% in the guaifenesin market. Retail pharmacies and online pharmacies also play significant roles, but hospital pharmacies remain the primary channel due to the high demand for these medications in healthcare settings[3].

Challenges and Opportunities

Availability of Substitutes

One of the major challenges facing the guaifenesin market is the availability of substitutes. However, the unique combination of guaifenesin with dextromethorphan, which acts as both an expectorant and a cough suppressant, maintains its market position[1].

Side Effects and Safety

While guaifenesin and dextromethorphan combinations are effective, they come with potential side effects such as drowsiness. Healthcare providers must be consulted before use, especially for patients with persistent or chronic coughs or those taking other medications[5].

Financial Trajectory

The financial trajectory of the guaifenesin market is promising, with significant growth projected over the next decade. Here are some key financial highlights:

  • Revenue Growth: The market is expected to grow from US$ 1.3 billion in 2023 to US$ 2.7 billion by 2033, at a CAGR of 7.4%[3].
  • Market Share: North America holds the largest market share, with 39.7% in 2023, driven by the high demand for respiratory treatments[3].
  • Segment Growth: The cough suppressant segment, which includes combinations with dextromethorphan, holds a significant share of 48.3% in the market[3].

Key Takeaways

  • The global guaifenesin market is driven by the increasing prevalence of respiratory conditions and advancements in the pharmaceutical sector.
  • North America is the fastest-growing region, with a high demand for guaifenesin in hospitals and clinics.
  • The combination of guaifenesin with dextromethorphan is a key product segment, offering both expectorant and cough suppressant properties.
  • The market faces challenges from substitutes but maintains its position due to its efficacy and safety profile.
  • The financial trajectory indicates significant growth, with the market expected to reach US$ 2.7 billion by 2033.

FAQs

What is the primary use of guaifenesin and dextromethorphan hydrobromide?

Guaifenesin and dextromethorphan hydrobromide are used in combination to treat coughs, chest congestion, and mucus buildup, acting as an expectorant and a cough suppressant, respectively[2].

Which region dominates the guaifenesin market?

North America dominates the guaifenesin market, driven by the high demand for respiratory treatments and the development of medical infrastructure[1][3].

What are the potential side effects of guaifenesin and dextromethorphan combinations?

Potential side effects include drowsiness, and patients should consult healthcare providers before use, especially if they have persistent or chronic coughs or are taking other medications[5].

How does the COVID-19 pandemic impact the guaifenesin market?

The COVID-19 pandemic initially disrupted production and supply chains but later led to a surge in demand for cough and cold medications, contributing to market growth[1].

What is the projected market size of the global guaifenesin market by 2033?

The global guaifenesin market is expected to be worth around US$ 2.7 billion by 2033, growing at a CAGR of 7.4% from 2023[3].

Cited Sources

  1. IndustryARC: Guaifenesin Market Size Report, 2022-2027.
  2. DailyMed: GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE tablet, extended release.
  3. Market.US: Global Guaifenesin Market Size, Share | CAGR Of 7.4%.
  4. Mordor Intelligence: Dextromethorphan Market Size & Share Analysis - Growth Trends.
  5. Cleveland Clinic: Dextromethorphan Guaifenesin (Mucinex DM) oral solution.

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