You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: January 10, 2025

GUANIDINE HYDROCHLORIDE Drug Patent Profile


✉ Email this page to a colleague

« Back to Dashboard


When do Guanidine Hydrochloride patents expire, and what generic alternatives are available?

Guanidine Hydrochloride is a drug marketed by Merck Sharp Dohme and is included in one NDA.

The generic ingredient in GUANIDINE HYDROCHLORIDE is guanidine hydrochloride. There are eight drug master file entries for this compound. Additional details are available on the guanidine hydrochloride profile page.

AI Research Assistant
Questions you can ask:
  • What is the 5 year forecast for GUANIDINE HYDROCHLORIDE?
  • What are the global sales for GUANIDINE HYDROCHLORIDE?
  • What is Average Wholesale Price for GUANIDINE HYDROCHLORIDE?
Summary for GUANIDINE HYDROCHLORIDE
US Patents:0
Applicants:1
NDAs:1
Raw Ingredient (Bulk) Api Vendors: 176
Clinical Trials: 8
Patent Applications: 318
What excipients (inactive ingredients) are in GUANIDINE HYDROCHLORIDE?GUANIDINE HYDROCHLORIDE excipients list
DailyMed Link:GUANIDINE HYDROCHLORIDE at DailyMed
Drug patent expirations by year for GUANIDINE HYDROCHLORIDE
Recent Clinical Trials for GUANIDINE HYDROCHLORIDE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Children's Hospital of Fudan UniversityPhase 4
St. Louis UniversityEarly Phase 1
Washington University School of MedicineEarly Phase 1

See all GUANIDINE HYDROCHLORIDE clinical trials

US Patents and Regulatory Information for GUANIDINE HYDROCHLORIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Merck Sharp Dohme GUANIDINE HYDROCHLORIDE guanidine hydrochloride TABLET;ORAL 001546-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

GUANIDINE HYDROCHLORIDE Market Analysis and Financial Projection

Market Dynamics and Financial Trajectory of Guanidine Hydrochloride

Introduction to Guanidine Hydrochloride

Guanidine hydrochloride, with the chemical formula CH₆ClN₃, is a compound widely used as a protein denaturant. It plays a crucial role in various biochemical and pharmaceutical applications, including the denaturation of proteins and the purification of biological samples.

Market Size and Growth

The global guanidine hydrochloride market has been experiencing steady growth. As of 2022, the market size was valued at USD 49.56 million. It is projected to expand at a Compound Annual Growth Rate (CAGR) of 7.4% during the forecast period from 2024 to 2032[4].

By 2032, the market is expected to reach approximately USD 0.07 billion, up from USD 0.05 billion in 2024, exhibiting a CAGR of 5.8%[1].

Regional Market Share

The Asia-Pacific region holds a leading position in the guanidine hydrochloride market share as of 2023. This dominance is driven by the region's robust pharmaceutical and biotechnology sectors, which heavily rely on guanidine hydrochloride for various applications[1].

Key Drivers of the Market

Several factors are driving the growth of the guanidine hydrochloride market:

  • Applications in Protein Denaturation: Guanidine hydrochloride is extensively used in the process of denaturing proteins, which is crucial in biochemical research and pharmaceutical development[1].
  • Purification Processes: It aids in the purification of biological samples, making it an essential reagent in laboratories and industrial settings.
  • Pharmaceutical Industry: The increasing demand for pharmaceutical-grade guanidine hydrochloride in drug development and manufacturing processes is a significant driver[3].

Major Players in the Market

The guanidine hydrochloride market is dominated by several key companies, including:

  • AlzChem AG
  • Vihita Chem
  • SANWA Chemical
  • Tangshan Sanding Chem
  • Jinchi Chemicals
  • Sihong Yuecheng Fine Chem
  • Jinhua Qianjiang Fine Chem
  • Hangzhou Xiangshun Chem
  • Wuxi Kalider Industrial
  • Kunshan Kunhua[1].

Applications and Uses

Guanidine hydrochloride has diverse applications across various industries:

  • Biochemical Research: It is used to denature proteins, which helps in understanding protein structure and function.
  • Pharmaceuticals: It is used in the purification and formulation of drugs.
  • Biotechnology: It plays a role in the purification of biological samples and in the development of biotechnological products[2].

Effects on Protein Folding

Guanidine hydrochloride is known for its ability to denature proteins, affecting their folding thermodynamics. Studies using all-atom Go models and the Molecular Transfer Model have shown that guanidine hydrochloride concentration linearly affects the folding temperature and free energies of proteins. This is particularly relevant in the study of globular proteins, where the compound helps in understanding the folding mechanisms and stabilities of different protein variants[5].

Financial Trajectory

The financial trajectory of the guanidine hydrochloride market is promising, with steady growth anticipated over the next decade. Here are some key financial highlights:

  • Market Value: Expected to grow from USD 49.56 million in 2022 to approximately USD 0.07 billion by 2032[1][4].
  • CAGR: Projected to exhibit a CAGR of 7.4% during the forecast period, indicating robust growth[4].
  • Revenue Streams: The revenue is expected to come from increased demand in pharmaceutical, biotechnological, and biochemical research sectors.

Challenges and Opportunities

While the market is growing, there are challenges and opportunities to consider:

  • Regulatory Compliance: Companies must adhere to stringent regulatory standards, particularly in the pharmaceutical sector.
  • Research and Development: Continuous R&D is necessary to explore new applications and improve existing processes.
  • Market Expansion: There is an opportunity for market expansion, especially in regions with growing biotechnology and pharmaceutical industries.

Key Takeaways

  • The global guanidine hydrochloride market is expected to grow significantly, driven by its applications in protein denaturation and purification.
  • The Asia-Pacific region is a key market due to its strong pharmaceutical and biotechnology sectors.
  • Major players include AlzChem AG, Vihita Chem, and others.
  • The compound plays a crucial role in biochemical research and pharmaceutical development.
  • Financial growth is anticipated, with a CAGR of 7.4% during the forecast period.

FAQs

What is the expected market size of guanidine hydrochloride by 2032?

The global guanidine hydrochloride market is expected to reach approximately USD 0.07 billion by 2032[1].

What is the CAGR of the guanidine hydrochloride market from 2024 to 2032?

The guanidine hydrochloride market is expected to exhibit a CAGR of 7.4% during the forecast period[4].

What are the primary applications of guanidine hydrochloride?

Guanidine hydrochloride is primarily used in the denaturation of proteins and in the purification of biological samples[1][2].

Which region holds the leading position in the guanidine hydrochloride market?

The Asia-Pacific region holds the leading position in the guanidine hydrochloride market as of 2023[1].

Who are the major players in the guanidine hydrochloride market?

Major players include AlzChem AG, Vihita Chem, SANWA Chemical, and several others[1].

Sources

  1. Business Research Insights: Guanidine Hydrochloride Market Share | Growth Report, 2032
  2. Ambeed: Guanidine HCI - Ambeed.com
  3. Market Research Reports: Global Pharmaceutical Grade Guanidine Hydrochloride Market Research Report 2024
  4. News Channel Nebraska: Guanidine Hydrochloride Market Outlook and Future Trends: 2024-2032
  5. BioRxiv: Temperature and Guanidine Hydrochloride effects on the folding of WW domain proteins

More… ↓

⤷  Subscribe

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.