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Last Updated: December 22, 2024

INDOCYANINE GREEN Drug Patent Profile


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Which patents cover Indocyanine Green, and what generic alternatives are available?

Indocyanine Green is a drug marketed by Renew Pharms and is included in one NDA.

The generic ingredient in INDOCYANINE GREEN is indocyanine green. There are three drug master file entries for this compound. Three suppliers are listed for this compound. Additional details are available on the indocyanine green profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Indocyanine Green

A generic version of INDOCYANINE GREEN was approved as indocyanine green by RENEW PHARMS on November 21st, 2007.

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Drug patent expirations by year for INDOCYANINE GREEN
Recent Clinical Trials for INDOCYANINE GREEN

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Stryker NordicPhase 4
University of Alabama at BirminghamPhase 4
Northwestern UniversityPhase 4

See all INDOCYANINE GREEN clinical trials

Medical Subject Heading (MeSH) Categories for INDOCYANINE GREEN
Anatomical Therapeutic Chemical (ATC) Classes for INDOCYANINE GREEN
Paragraph IV (Patent) Challenges for INDOCYANINE GREEN
Tradename Dosage Ingredient Strength NDA ANDAs Submitted Submissiondate
SPY AGENT GREEN KIT For Injection indocyanine green 25 mg/vial 211580 1 2022-11-28

US Patents and Regulatory Information for INDOCYANINE GREEN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Renew Pharms INDOCYANINE GREEN indocyanine green INJECTABLE;INJECTION 040811-001 Nov 21, 2007 RX No Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

INDOCYANINE GREEN Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory of Indocyanine Green

Market Overview

The Indocyanine Green (ICG) market is experiencing significant growth, driven by its versatile applications in medical imaging, particularly in ophthalmology, cardiology, and neurosurgery. Here are the key dynamics and financial projections for this market.

Market Size and Growth

The global ICG market is projected to grow substantially over the next few years. As of 2024, the market size is estimated to be around $52 million, and it is anticipated to reach $68 million by 2030, with a Compound Annual Growth Rate (CAGR) of 4.8%[1][4].

However, another forecast suggests a slightly higher growth rate, with the market estimated to reach $85.6 million by 2030, at a CAGR of 7.89%[4].

Key Drivers

Expanding Use in Fluorescence-Guided Surgery

The increasing use of ICG in fluorescence-guided surgery is a significant driver. Surgeons rely on ICG to identify tumors, assess blood flow, and ensure precise surgical interventions, particularly in oncology and cardiovascular procedures[1].

Rising Adoption in Ophthalmology

ICG is widely used in ophthalmology for retinal angiography to diagnose and monitor conditions such as macular degeneration and diabetic retinopathy. This trend reflects the growing focus on early diagnosis and management of vision-related disorders[1].

Integration with Advanced Imaging Technologies

The integration of ICG into hybrid imaging systems is transforming diagnostic practices. These systems combine multiple imaging modalities, offering enhanced visualization and comprehensive diagnostic insights[1].

Research and Development

The growing focus on research and development is introducing new applications for ICG, including regenerative medicine and tissue engineering. This innovation highlights the market’s potential for growth in cutting-edge medical fields[1].

Applications and Segments

Ophthalmology

The ophthalmology segment is expected to expand significantly, retaining its position throughout the forecast period. ICG is crucial for diagnosing and monitoring various eye conditions[3].

Neurosurgery and Cardiovascular Procedures

ICG is also widely used in neurosurgery and cardiovascular procedures. Its application in sentinel lymph node mapping for various cancers and in the removal of deep-seated arterio-venous malformations is notable[2].

Liver Diseases and Other Applications

ICG is used in diagnosing and managing liver diseases, as well as in other medical conditions such as Behcet's disease, choroidal melanoma, and critical limb ischemia[2].

Regional Analysis

North America and Europe

These regions dominate the ICG market due to their advanced healthcare infrastructure and strong focus on research and development. However, emerging economies in Asia-Pacific and Latin America are also showing promising growth[4].

Competitive Landscape

The market is competitive, with key players such as Diagnostic Green, SERB, Daiichi Sankyo Company, Santen Pharmaceutical Co., Ltd., Aurolab, Yichuang, and Eisai. These companies are focusing on strategic alliances, mergers, and expanding their regional footprints to maintain a competitive edge[1][4].

Impact of COVID-19

The COVID-19 pandemic had a significant impact on the ICG market, leading to a decline in demand due to the deferral or cancellation of elective medical procedures. However, as the pandemic receded, the market saw a recovery with medical facilities resuming elective procedures and governments emphasizing medical research and healthcare framework enhancements[4].

Financial Trajectory

Revenue Forecast

The market is expected to grow from $52 million in 2024 to $68 million by 2030, with a CAGR of 4.8%[1]. Alternatively, another forecast projects the market to reach $85.6 million by 2030, with a CAGR of 7.89%[4].

Segment Analysis

The Pharma Grade segment accounted for a noticeable share of the global ICG market in 2023 and is projected to experience significant growth in the near future. The ophthalmology segment is also expected to expand at a significant CAGR throughout the forecast period[3].

Technological Trends

The ICG market is witnessing innovation with the integration of ICG into advanced imaging technologies, such as hybrid imaging systems. This trend underscores the importance of innovation in improving patient outcomes[1].

Market Recovery and Future Outlook

As the healthcare sector recovers from the pandemic, the ICG market is expected to continue its growth trajectory. Companies are optimizing their supply chains, pivoting towards local sourcing, and amplifying their digital outreach to meet the evolving needs of healthcare professionals[4].

Key Takeaways

  • The global ICG market is projected to grow from $52 million in 2024 to $68 million by 2030, with a CAGR of 4.8%.
  • The market is driven by expanding use in fluorescence-guided surgery, rising adoption in ophthalmology, and integration with advanced imaging technologies.
  • Key applications include ophthalmology, neurosurgery, and cardiovascular procedures.
  • North America and Europe dominate the market, but emerging economies are showing promising growth.
  • The market recovered from the COVID-19 pandemic and is expected to continue growing as healthcare sectors enhance their infrastructure and research.

FAQs

1. What is the projected market size of Indocyanine Green by 2030?

The market is projected to reach $68 million by 2030, with a CAGR of 4.8%[1].

2. What are the primary applications of Indocyanine Green?

Primary applications include ophthalmology, neurosurgery, cardiovascular procedures, and liver diseases[1][2].

3. How did the COVID-19 pandemic affect the Indocyanine Green market?

The pandemic led to a decline in demand due to the deferral or cancellation of elective medical procedures, but the market has since recovered as healthcare facilities resumed these procedures[4].

4. Which regions dominate the Indocyanine Green market?

North America and Europe dominate the market, but emerging economies in Asia-Pacific and Latin America are also growing[4].

5. What are the key trends reshaping the Indocyanine Green market?

Key trends include the integration of ICG into advanced imaging technologies, rising adoption in ophthalmology, and expanding use in fluorescence-guided surgery[1][4].

Cited Sources:

  1. Global Indocyanine Green Market Insights, Forecast to 2030 - Valuates Reports
  2. Indocyanine Green Angiography - Medical Clinical Policy Bulletins - Aetna
  3. Indocyanine Green Market Report 2024 (Global Edition) - Cognitive Market Research
  4. Indocyanine Green Market - Global Growth Insights - Global Growth Insights

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