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Last Updated: December 22, 2024

KEFZOL Drug Patent Profile


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When do Kefzol patents expire, and what generic alternatives are available?

Kefzol is a drug marketed by Acs Dobfar and Lilly and is included in two NDAs.

The generic ingredient in KEFZOL is cefazolin sodium. There are twenty-seven drug master file entries for this compound. Twenty suppliers are listed for this compound. Additional details are available on the cefazolin sodium profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Kefzol

A generic version of KEFZOL was approved as cefazolin sodium by SANDOZ on December 9th, 1988.

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Summary for KEFZOL
Drug patent expirations by year for KEFZOL
Recent Clinical Trials for KEFZOL

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Ng Teng Fong General HospitalPhase 3
John Hunter HospitalPhase 3
Singapore General HospitalPhase 3

See all KEFZOL clinical trials

US Patents and Regulatory Information for KEFZOL

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Acs Dobfar KEFZOL cefazolin sodium INJECTABLE;INJECTION 061773-003 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Lilly KEFZOL cefazolin sodium INJECTABLE;INJECTION 062557-001 Sep 10, 1985 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Acs Dobfar KEFZOL cefazolin sodium INJECTABLE;INJECTION 061773-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Acs Dobfar KEFZOL cefazolin sodium INJECTABLE;INJECTION 061773-004 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Acs Dobfar KEFZOL cefazolin sodium INJECTABLE;INJECTION 061773-005 Sep 8, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

KEFZOL Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory of Cefazolin Sodium (KEFZOL)

Introduction to Cefazolin Sodium (KEFZOL)

Cefazolin sodium, commonly known by the brand name KEFZOL, is a first-generation cephalosporin antibiotic widely used for surgical prophylaxis and the treatment of various bacterial infections. Here, we delve into the market dynamics and financial trajectory of this crucial antimicrobial agent.

Market Size and Revenue

The global cefazolin sodium market has been experiencing significant growth, driven by increasing demand for antimicrobial drugs. From 2019 to 2023, the market has shown a steady increase in revenue, with projections indicating continued growth until 2031. The market size is estimated to expand substantially, with the adult segment expected to retain a significant share due to its widespread use in surgical prophylaxis[1][4].

Market Segmentation

By Type

The cefazolin sodium market is segmented into several types, including:

  • Antimicrobial Drugs: This segment accounts for a noticeable share of the global market and is projected to experience significant growth.
  • Antibiotics: Cefazolin falls under this category, which is a key driver of the market.
  • Cephalosporins: As a first-generation cephalosporin, cefazolin sodium is a major player in this segment.
  • First-Generation Cephalosporins: This specific segment is expected to maintain its market position due to the drug's efficacy and established use[1][4].

By Application

The market is also segmented by application:

  • Adult: This segment is expected to expand at a significant CAGR, retaining its position throughout the forecast period.
  • Children: Although the pediatric segment is smaller, it is still crucial, especially in cases where pediatric patients require surgical prophylaxis[1][4].

Regional Outlook

The global cefazolin sodium market is analyzed across five major regions. The regional analysis provides insights into market trends, growth rates, and revenue forecasts at the country and regional levels. The regions expected to dominate the market include North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa. Each region's market dynamics are influenced by factors such as healthcare infrastructure, regulatory policies, and the prevalence of bacterial infections[1][4].

Drivers and Opportunities

Several factors drive the growth of the cefazolin sodium market:

  • Increasing Prevalence of Bacterial Infections: The rising incidence of bacterial infections, particularly those requiring surgical interventions, boosts the demand for cefazolin sodium.
  • Technological Advancements: Improvements in healthcare infrastructure and the adoption of advanced medical technologies enhance the market's growth potential.
  • Investments in R&D: Significant investments in research and development by pharmaceutical companies contribute to the market's expansion.
  • Growing Need for Surgical Prophylaxis: Cefazolin sodium's efficacy in preventing surgical site infections makes it a preferred choice, driving its market growth[1][4].

Restraints and Challenges

Despite the growth, the market faces several challenges:

  • Antimicrobial Resistance: The increasing resistance to antibiotics, including cephalosporins, poses a significant threat to the market.
  • Regulatory Hurdles: Strict regulatory frameworks and the need for continuous monitoring of antibiotic use can restrain market growth.
  • Side Effects and Allergic Reactions: Adverse reactions to cefazolin sodium, such as allergic reactions, can limit its use in certain patient populations[1][4].

Key Players and Competitive Landscape

The cefazolin sodium market is competitive, with several key players focusing on strategy building and portfolio expansion:

  • Acs Dobfar Spa
  • Olon
  • Other pharmaceutical companies are also investing in research and development to strengthen their market positions[1][4].

Financial Trajectory

The financial trajectory of the cefazolin sodium market is promising, with projected revenue growth at the global, regional, and country levels. Here are some key financial insights:

  • Revenue Growth: The market is expected to see significant revenue growth from 2025 to 2031, driven by increasing demand and expanding applications.
  • CAGR: The adult segment, in particular, is expected to expand at a significant Compound Annual Growth Rate (CAGR) during the forecast period.
  • Market Size: The global market size is estimated to increase substantially, reflecting the drug's importance in antimicrobial therapy[1][4].

Impact of COVID-19

The COVID-19 pandemic has had a mixed impact on the cefazolin sodium market:

  • Increased Demand: The pandemic led to an increased need for antimicrobial drugs, including cefazolin sodium, due to the higher incidence of secondary bacterial infections.
  • Supply Chain Disruptions: However, the pandemic also caused supply chain disruptions, affecting the production and distribution of the drug[4].

Clinical Guidelines and Recommendations

Cefazolin sodium is widely recommended in clinical guidelines for surgical prophylaxis:

  • ASHP Guidelines: According to the American Society of Health-System Pharmacists (ASHP), cefazolin is the drug of choice for prophylaxis in many surgical procedures due to its efficacy and safety profile[3].

Consumer Behavior and Demand

Consumer behavior and demand for cefazolin sodium are influenced by several factors:

  • Healthcare Provider Recommendations: The drug's widespread recommendation by healthcare providers drives its demand.
  • Patient Outcomes: Positive patient outcomes following the use of cefazolin sodium for surgical prophylaxis further increase its demand[1][4].

Technological Trends

Technological advancements play a crucial role in the cefazolin sodium market:

  • Rapid Testing and Point-of-Care Diagnosis: Improvements in diagnostic technologies enhance the ability to identify bacterial infections quickly, increasing the demand for antimicrobial drugs like cefazolin sodium.
  • Precision Medicine: The growing adoption of precision medicine approaches also contributes to the market's growth by ensuring more targeted and effective treatment strategies[4].

SWOT Analysis

Strengths

  • Established Efficacy: Cefazolin sodium has a well-established efficacy profile in preventing surgical site infections.
  • Wide Recommendations: It is widely recommended in clinical guidelines.

Weaknesses

  • Antimicrobial Resistance: The increasing resistance to cephalosporins is a significant concern.
  • Side Effects: Allergic reactions and other side effects can limit its use.

Opportunities

  • Growing Demand: Increasing demand for antimicrobial drugs due to rising bacterial infections.
  • Technological Advancements: Improvements in healthcare infrastructure and diagnostic technologies.

Threats

  • Regulatory Changes: Strict regulatory frameworks can impact market growth.
  • Competitive Landscape: The presence of other antimicrobial agents in the market[1][4].

Key Takeaways

  • The cefazolin sodium market is expected to grow significantly until 2031, driven by increasing demand for antimicrobial drugs.
  • The adult segment will retain a significant share of the market.
  • Technological advancements and investments in R&D are key drivers of market growth.
  • Antimicrobial resistance and regulatory hurdles are major challenges.
  • Cefazolin sodium remains a preferred choice for surgical prophylaxis due to its efficacy and safety profile.

FAQs

Q: What are the primary applications of cefazolin sodium?

A: Cefazolin sodium is primarily used for surgical prophylaxis and the treatment of various bacterial infections, with a significant focus on adult patients[1][3].

Q: Which segment is expected to dominate the cefazolin sodium market?

A: The adult segment is expected to expand at a significant CAGR and retain its position throughout the forecast period[1][4].

Q: What are the key drivers of the cefazolin sodium market?

A: Key drivers include the increasing prevalence of bacterial infections, technological advancements, and investments in R&D[1][4].

Q: What are the major challenges facing the cefazolin sodium market?

A: Major challenges include antimicrobial resistance, regulatory hurdles, and side effects such as allergic reactions[1][4].

Q: Which regions are expected to dominate the global cefazolin sodium market?

A: North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa are expected to be the dominant regions in the global market[1][4].

Sources

  1. Cognitive Market Research: Cefazolin Sodium Market Report 2024 (Global Edition)
  2. MDPI: Early Bone Healing on Hydroxyapatite-Coated and Chemically Modified Titanium Implants
  3. ASHP: Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery
  4. Biospace: Cefazolin Sodium Market Trends, Revenue, Key Players, Growth, Share, and Forecast till 2027
  5. KCE: Proposals for a more effective antibiotic policy in Belgium

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