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Last Updated: April 2, 2025

MANNITOL 20% IN PLASTIC CONTAINER Drug Patent Profile


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When do Mannitol 20% In Plastic Container patents expire, and what generic alternatives are available?

Mannitol 20% In Plastic Container is a drug marketed by B Braun and Icu Medical Inc and is included in two NDAs.

The generic ingredient in MANNITOL 20% IN PLASTIC CONTAINER is mannitol. There are eighteen drug master file entries for this compound. Ten suppliers are listed for this compound. Additional details are available on the mannitol profile page.

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Summary for MANNITOL 20% IN PLASTIC CONTAINER
Drug patent expirations by year for MANNITOL 20% IN PLASTIC CONTAINER
Recent Clinical Trials for MANNITOL 20% IN PLASTIC CONTAINER

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University Hospital, GenevaPhase 3
Morten Hostrup, PhDN/A
University Hospital Inselspital, BerneEarly Phase 1

See all MANNITOL 20% IN PLASTIC CONTAINER clinical trials

Pharmacology for MANNITOL 20% IN PLASTIC CONTAINER
Drug ClassOsmotic Diuretic
Mechanism of ActionOsmotic Activity
Physiological EffectIncreased Diuresis

US Patents and Regulatory Information for MANNITOL 20% IN PLASTIC CONTAINER

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Icu Medical Inc MANNITOL 20% IN PLASTIC CONTAINER mannitol INJECTABLE;INJECTION 019603-004 Jan 8, 1990 AP RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
B Braun MANNITOL 20% IN PLASTIC CONTAINER mannitol INJECTABLE;INJECTION 020006-004 Jul 26, 1993 AP RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 2 of 2 entries

EU/EMA Drug Approvals for MANNITOL 20% IN PLASTIC CONTAINER

CompanyDrugnameInnProduct Number / IndicationStatusGenericBiosimilarOrphanMarketing AuthorisationMarketing Refusal
Pharmaxis Europe Limited Bronchitol mannitol EMEA/H/C/001252
Bronchitol is indicated for the treatment of cystic fibrosis (CF) in adults aged 18 years and above as an add-on therapy to best standard of care.
Authorised no no no 2012-04-13
>Company>Drugname>Inn>Product Number / Indication>Status>Generic>Biosimilar>Orphan>Marketing Authorisation>Marketing Refusal
Showing 1 to 1 of 1 entries

Mannitol Market Dynamics and Financial Trajectory: A Comprehensive Analysis

Market Overview

Mannitol, a polyol widely used in various industries including pharmaceuticals, food, and beverages, is experiencing significant growth driven by several key factors. Here’s a detailed look at the market dynamics and financial trajectory of Mannitol, particularly focusing on Mannitol 20% in plastic containers.

Market Size and Growth

The global mannitol market was valued at approximately USD 418.65 million in 2022 and is projected to reach USD 890.31 million by 2033, growing at a CAGR of 7.1% from 2023 to 2033[2].

Product Type: Mannitol 20% in Plastic Containers

Mannitol 20% solution, often packaged in plastic containers, is a critical product in the market. This concentration is particularly used for treating conditions such as increased intracranial pressure, glaucoma, and advanced diuresis in patients with renal failure. The 20g/100 ml portion is expected to represent the largest revenue share among other product types due to its widespread medical applications[3].

Key Drivers

Several factors are driving the growth of the mannitol market:

Increasing Demand in Pharmaceuticals

Mannitol is extensively used in the pharmaceutical industry as an excipient in tablet formulations and for treating various medical conditions, including brain, kidney, and heart problems. The pharmaceutical sector is expected to grow at a CAGR of 7.91% over the forecast period, driven by the increasing demand for oral care products like orally-disintegrating tablets (ODTs) and chewable tablets[2].

Growing Health Awareness

The rise in health-conscious consumers, especially post-pandemic, is boosting the demand for mannitol. Its use in low-calorie sweeteners and sugar-free products is particularly appealing to consumers concerned about their health[3].

Technological Advances

Technological advancements in production, packaging, and distribution are enhancing the efficiency and appeal of mannitol products. Innovations such as sustainable packaging and the use of blockchain and IoT technologies for supply chain management are also driving growth[1].

Regional Analysis

The market for mannitol is geographically diverse, with different regions contributing significantly:

North America

North America is expected to hold the largest revenue share, driven by the increasing prevalence of acute renal failure and trauma, and the strong healthcare infrastructure in the region. Positive reimbursement policies for parenteral IV treatments also support market growth[3].

Europe

Europe is another significant market, with mannitol being used for treating cystic fibrosis and other conditions. The region's well-developed healthcare system and presence of key players contribute to its market share[3].

Asia Pacific

The Asia Pacific region is expected to register a strong CAGR due to the rising incidence of kidney failure, growing demand for urology procedures, and the rapid advancement of the pharmaceutical sector in countries like China, Japan, and India[3].

Challenges and Restraints

Despite the positive growth trajectory, the mannitol market faces several challenges:

Supply Chain Disruptions

Global events such as the COVID-19 pandemic and geopolitical tensions have caused supply chain disruptions, affecting the availability and pricing of mannitol[1].

Regulatory Compliance

Stringent regulations on food safety and labeling, as well as compliance with pharmaceutical standards, pose significant challenges for manufacturers[1].

Competition and Raw Material Costs

The market is highly competitive, with several key players vying for market share. Fluctuating raw material prices and high production costs also act as restraints[2].

Financial Trajectory

Here are some key financial metrics and projections for the mannitol market:

  • Market Value in 2022: Approximately USD 418.65 million[2].
  • Projected Market Value in 2033: USD 890.31 million[2].
  • CAGR from 2023 to 2033: 7.1%[2].
  • Volume Sales in 2023: Expected to rise at 5.62%, with shipments reaching 66,998 MT[2].

Market Segmentation

The mannitol market is segmented based on product type, application, and end-user:

  • By Product Type: The market includes various concentrations such as 5g/100 ml, 10g/100 ml, 15g/100 ml, 20g/100 ml, and 25g/100 ml, with the 20g/100 ml segment being the most dominant[3].
  • By Application: Key applications include hospital pharmacies, retail pharmacies, and online pharmacies. The pharmaceutical sector is the leading segment in terms of end-use[2][3].

Key Players and Market Strategies

Major players in the mannitol market include Roquette, Cargill, SPI Polyols, Inc., and others. These companies are focusing on strategies such as mergers and acquisitions, product diversification, and technological innovations to maintain their competitive edge[4].

Impact of Global Events

The COVID-19 pandemic had a significant impact on the mannitol market, causing production shutdowns and supply chain disruptions. However, as economies recover, the market is expected to rebound. Other global events, such as the Ukraine-Russia war and ongoing recession, also pose challenges but are being managed through adaptive strategies[3].

Conclusion

The mannitol market, particularly the segment involving Mannitol 20% in plastic containers, is poised for significant growth driven by increasing demand in pharmaceuticals, growing health awareness, and technological advancements. Despite challenges such as supply chain disruptions and regulatory compliance, the market is expected to reach USD 890.31 million by 2033, growing at a CAGR of 7.1%.

Key Takeaways

  • The global mannitol market is projected to grow at a CAGR of 7.1% from 2023 to 2033.
  • Mannitol 20% solution is a key product, particularly used in medical treatments.
  • The pharmaceutical sector is the leading end-use segment, growing at a CAGR of 7.91%.
  • North America, Europe, and Asia Pacific are significant regional markets.
  • Supply chain disruptions, regulatory compliance, and competition are key challenges.

FAQs

Q: What is the projected market value of mannitol by 2033? A: The projected market value of mannitol by 2033 is USD 890.31 million[2].

Q: What is the primary use of Mannitol 20% solution? A: Mannitol 20% solution is primarily used for treating conditions such as increased intracranial pressure, glaucoma, and advanced diuresis in patients with renal failure[3].

Q: Which region holds the largest revenue share in the mannitol market? A: North America holds the largest revenue share in the mannitol market, driven by the strong healthcare infrastructure and increasing prevalence of acute renal failure and trauma[3].

Q: What are the key challenges facing the mannitol market? A: Key challenges include supply chain disruptions, stringent regulations on food safety and labeling, competition, and high production costs[1][2].

Q: Who are the major players in the mannitol market? A: Major players include Roquette, Cargill, SPI Polyols, Inc., and others, focusing on strategies such as mergers and acquisitions, product diversification, and technological innovations[4].

Sources

  1. Research and Markets: Mannitol Market Size, Competitors, Trends & Forecast Report.
  2. Future Market Insights: Mannitol Market Size, Share, Outlook & Forecast by 2033.
  3. SNS Insider: Mannitol Market Size & Share Report Forecast 2023-2030.
  4. Grand View Research: Mannitol Market Size Worth $418.3 Million By 2024.

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