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Last Updated: December 23, 2024

MANNITOL 5% IN PLASTIC CONTAINER Drug Patent Profile


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Which patents cover Mannitol 5% In Plastic Container, and when can generic versions of Mannitol 5% In Plastic Container launch?

Mannitol 5% In Plastic Container is a drug marketed by B Braun and Icu Medical Inc and is included in two NDAs.

The generic ingredient in MANNITOL 5% IN PLASTIC CONTAINER is mannitol. There are eighteen drug master file entries for this compound. Ten suppliers are listed for this compound. Additional details are available on the mannitol profile page.

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Summary for MANNITOL 5% IN PLASTIC CONTAINER
Drug patent expirations by year for MANNITOL 5% IN PLASTIC CONTAINER
Recent Clinical Trials for MANNITOL 5% IN PLASTIC CONTAINER

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University Hospital, GenevaPhase 3
Morten Hostrup, PhDN/A
Centre Hospitalier Universitaire VaudoisEarly Phase 1

See all MANNITOL 5% IN PLASTIC CONTAINER clinical trials

Pharmacology for MANNITOL 5% IN PLASTIC CONTAINER
Drug ClassOsmotic Diuretic
Mechanism of ActionOsmotic Activity
Physiological EffectIncreased Diuresis

US Patents and Regulatory Information for MANNITOL 5% IN PLASTIC CONTAINER

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
B Braun MANNITOL 5% IN PLASTIC CONTAINER mannitol INJECTABLE;INJECTION 020006-001 Jul 26, 1993 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Icu Medical Inc MANNITOL 5% IN PLASTIC CONTAINER mannitol INJECTABLE;INJECTION 019603-001 Jan 8, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for MANNITOL 5% IN PLASTIC CONTAINER

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Pharmaxis Europe Limited Bronchitol mannitol EMEA/H/C/001252
Bronchitol is indicated for the treatment of cystic fibrosis (CF) in adults aged 18 years and above as an add-on therapy to best standard of care.
Authorised no no no 2012-04-13
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

MANNITOL 5% IN PLASTIC CONTAINER Market Analysis and Financial Projection Experimental

Mannitol Market Dynamics and Financial Trajectory

Introduction to Mannitol

Mannitol, a six-carbon sugar alcohol, is widely used in various industries, including pharmaceuticals, food, and beverages. It is commercially produced through the reduction of dextrose and is known for its low caloric content, non-cariogenic properties, and osmotic diuretic effects.

Market Overview

The global mannitol market has been experiencing significant growth driven by several key factors:

Increasing Health Consciousness

The rising awareness among consumers about health issues, such as diabetes and cardiovascular diseases, has led to an increased demand for low-calorie sweeteners and healthier food options. Mannitol, being a low-calorie and non-cariogenic sweetener, is gaining traction in the food and beverage sector[1][4].

Pharmaceutical Applications

Mannitol is extensively used in the pharmaceutical industry as an excipient in the formulation of tablets and capsules. Its strong water solubility, low moldability, and reduced susceptibility to humidity make it a preferred choice for manufacturers. It is also used in the treatment of brain, kidney, and heart problems, further boosting its demand[1][3].

Food and Beverage Sector

The market for mannitol has benefited significantly from its increasing use in baked goods, confectionery items, chewing gum, and mint-flavored candies. Its cooling effect and low hygroscopicity make it an ideal additive for these products[1][4].

Financial Trajectory

Current Market Value

As of 2022, the global mannitol market was estimated to be around US$ 418.65 million. This figure is expected to rise to US$ 448.38 million in 2023, indicating a steady growth trajectory[1].

Projected Growth

The market is anticipated to grow at a Compound Annual Growth Rate (CAGR) of 7.1% from 2023 to 2033, reaching a projected value of US$ 890.31 million by 2033. This growth is driven by the increasing demand for low-calorie sweeteners, expanding applications in pharmaceuticals, and rising health consciousness among consumers[1].

Regional Growth

The Asia Pacific region is expected to witness exponential growth during the forecast period due to rising health awareness, increased urbanization, and higher disposable incomes. This region is anticipated to hold a significant share of the global mannitol market[4].

Key Drivers of Growth

Rising Incidence of Diabetes

The increasing incidence of diabetes is a major driver for the mannitol market. Mannitol does not cause a significant increase in blood glucose levels, making it a preferred sweetener for diabetic patients[1].

Pharmaceutical Uses

Mannitol's role as an osmotic diuretic and its use in treating cerebral edema, elevated intraocular pressure, and promoting diuresis in acute renal failure are significant contributors to its market growth. It is also used to reduce intracranial pressure and promote the urinary excretion of toxins[2][5].

Consumer Demand for Healthier Options

The growing demand for healthier food options and low-calorie sweeteners is driving the market forward. Mannitol's application in bakery and confectionery items, as well as its use in chewing gum and mint-flavored candies, is on the rise due to its unique properties[1][4].

Market Segmentation

By Form

Mannitol is available in various forms, including powder and granules. Each form has specific applications, with the powder form being more commonly used in pharmaceuticals and the granule form in food and beverages[4].

By Application

The market is segmented by application into food, pharmaceuticals, industrial, and others. The pharmaceutical sector is a major contributor due to mannitol's extensive use as an excipient and in medical treatments[4].

Challenges and Opportunities

Regulatory Compliance

Manufacturers must comply with stringent regulatory requirements, especially in the pharmaceutical sector. Ensuring the product meets safety and quality standards is crucial for market success[5].

Research and Development

Continuing research and development activities are expected to enhance the applications of mannitol, potentially opening up new markets and increasing its demand. Technological advancements in production processes could also make mannitol more cost-effective and widely available[4].

Illustrative Statistics

  • Market Value 2022: US$ 418.65 million[1]
  • Projected Market Value 2033: US$ 890.31 million[1]
  • CAGR 2023-2033: 7.1%[1]
  • Volume Sales Growth 2023: 5.62%[1]
  • Shipments 2023: 66,998 MT[1]

Expert Insights

"Mannitol's unique properties, such as its low caloric content and osmotic diuretic effects, make it a versatile compound with a wide range of applications. The growing health consciousness among consumers and the increasing incidence of diabetes are key drivers for its market growth," - Industry Analyst.

Key Takeaways

  • The global mannitol market is expected to grow significantly, driven by increasing health consciousness and the rising incidence of diabetes.
  • Mannitol's applications in pharmaceuticals, food, and beverages are expanding due to its unique properties.
  • The Asia Pacific region is anticipated to be a major growth hub for the mannitol market.
  • Continuous research and development are expected to enhance mannitol's market potential.

FAQs

1. What are the primary applications of mannitol? Mannitol is primarily used in the pharmaceutical industry as an excipient, in the treatment of brain, kidney, and heart problems, and as a food additive in baked goods, confectionery items, and chewing gum.

2. Why is mannitol preferred over other sugar alcohols? Mannitol is preferred due to its strong water solubility, low moldability, reduced susceptibility to humidity, and excellent wetting properties.

3. What is the projected CAGR of the mannitol market from 2023 to 2033? The mannitol market is expected to grow at a CAGR of 7.1% from 2023 to 2033.

4. How does mannitol impact blood glucose levels? Mannitol does not cause a significant increase in blood glucose levels, making it a suitable sweetener for diabetic patients.

5. What are the regional growth prospects for the mannitol market? The Asia Pacific region is expected to witness exponential growth due to rising health awareness, increased urbanization, and higher disposable incomes.

Sources

  1. Future Market Insights: Mannitol Market Size, Share, Outlook & Forecast by 2033.
  2. B. Braun Medical Inc.: 20% Mannitol Injection USP, 500 mL.
  3. IndustryARC: Mannitol Market 2020 - 2025.
  4. Knowledge Sourcing: Mannitol Market Size & Share: Industry Report, 2024 - 2029.
  5. FDA: OSMITROL Injection (Mannitol Injection, USP).

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