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Last Updated: January 2, 2025

MD-76 Drug Patent Profile


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Summary for MD-76
US Patents:0
Applicants:2
NDAs:2
DailyMed Link:MD-76 at DailyMed
Drug patent expirations by year for MD-76

US Patents and Regulatory Information for MD-76

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Mallinckrodt MD-76 diatrizoate meglumine; diatrizoate sodium INJECTABLE;INJECTION 087073-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Liebel-flarsheim MD-76R diatrizoate meglumine; diatrizoate sodium INJECTABLE;INJECTION 019292-001 Sep 29, 1989 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

MD-76 Market Analysis and Financial Projection

Market Dynamics and Financial Trajectory for the Drug: MD-76

Introduction

MD-76, a radiopaque contrast medium composed of Diatrizoate Meglumine and Diatrizoate Sodium, is used in medical imaging to visualize the aorta and its major branches. To understand the market dynamics and financial trajectory of this drug, we need to delve into various aspects of the pharmaceutical market, including overall trends, competitive landscape, and financial projections.

Pharmaceutical Market Overview

The global pharmaceutical market is expected to grow significantly over the next few years. According to IQVIA, the global pharma market, excluding vaccines, is projected to reach $2,030 billion by 2027 at a CAGR of approximately 7% at constant exchange rates[1].

Market Segments and Growth Drivers

Developed Markets

In developed markets such as the EU4 (France, Germany, Italy, Spain) and the UK, the growth is driven by the launch of innovative new products, including novel therapies. Germany, for instance, is expected to contribute significantly to the aggregate increase in sales, with a CAGR of 5-6% from 2022 to 2027[1].

Pharmerging Markets

Pharmerging markets, including countries like China, Brazil, and India, are also experiencing rapid growth. These markets are expected to grow at a CAGR of 7-10% during the same period, driven by increasing healthcare spending and a growing middle class[1].

Competitive Landscape in Imaging Agents

The market for imaging agents, including radiopaque contrast media like MD-76, is competitive and influenced by several factors:

New Entries and Innovations

New therapeutic entries and innovations in the field of medical imaging can significantly impact market dynamics. For example, advancements in MRI and CT scan technologies have led to increased demand for contrast agents that offer better imaging quality and safety profiles[4].

Regulatory Environment

Regulatory approvals and compliance play a crucial role in the market trajectory of any pharmaceutical product. MD-76, being a well-established product, must continue to meet regulatory standards to maintain its market presence[5].

Financial Trajectory of MD-76

Pricing Dynamics

The pricing of pharmaceuticals, including MD-76, is influenced by various factors such as list prices, net prices, and rebates. Studies have shown that while list prices for brand-name drugs have increased significantly, net prices after rebates have slowed or halted in some cases. However, out-of-pocket spending for patients can still be affected, particularly for those paying deductibles or coinsurance[2].

Revenue Projections

Given the stable demand for radiopaque contrast media in medical imaging, MD-76 is likely to maintain a steady revenue stream. However, the overall revenue growth may be modest compared to innovative drugs in other therapeutic areas. The global market for imaging agents is expected to grow, but at a slower pace than the overall pharmaceutical market.

Cost Containment Measures

Governments and healthcare systems are implementing cost containment measures to control rising pharmaceutical expenditures. These measures can impact the pricing and revenue of established products like MD-76, especially if generic or biosimilar alternatives become available[1].

Market Adoption and Patient Access

Demographic Factors

The use of MD-76 and other imaging agents can be influenced by demographic factors such as age and gender. For instance, certain medical conditions that require imaging are more prevalent in older populations or specific ethnic groups[4].

Payer Dynamics

Medicare and other public payers play a significant role in the reimbursement of pharmaceuticals, including MD-76. Changes in payer policies and reimbursement rates can affect the financial trajectory of the drug[4].

Impact of Technological Advancements

Technological advancements in medical imaging can both enhance and challenge the market position of MD-76. New imaging technologies that require different or more advanced contrast agents could reduce demand for traditional products like MD-76. However, improvements in safety and efficacy can also increase the demand for established contrast media[4].

Global Vaccine and Imaging Market

While MD-76 is not a vaccine, the broader market for vaccines and other medical products can influence overall healthcare spending and priorities. The global vaccine market, excluding COVID-19 vaccines, has grown significantly and is expected to continue growing at a CAGR of 5-10% until 2027[1].

Key Takeaways

  • The global pharmaceutical market is expected to grow at a CAGR of approximately 7% until 2027.
  • Developed markets are driven by innovative new products, while pharmerging markets are growing rapidly due to increasing healthcare spending.
  • The market for imaging agents like MD-76 is influenced by regulatory, technological, and demographic factors.
  • Pricing dynamics, including list prices, net prices, and rebates, play a crucial role in the financial trajectory of pharmaceutical products.
  • Cost containment measures and payer dynamics can impact the revenue and market adoption of established products.

FAQs

What is the projected growth rate of the global pharmaceutical market until 2027?

The global pharmaceutical market, excluding vaccines, is expected to grow at a CAGR of approximately 7% until 2027[1].

How do list prices and net prices affect patient out-of-pocket spending?

Changes in list prices are not directly correlated with out-of-pocket spending for many patients, especially those who pay only copayments. However, patients paying deductibles or coinsurance may experience increases in out-of-pocket spending when list prices rise[2].

What role do technological advancements play in the market for imaging agents like MD-76?

Technological advancements can both enhance and challenge the market position of MD-76. New imaging technologies may require different contrast agents, but improvements in safety and efficacy can also increase demand for established products[4].

How do demographic factors influence the use of MD-76?

Demographic factors such as age and gender can influence the use of MD-76, as certain medical conditions requiring imaging are more prevalent in specific populations[4].

What are the key drivers of growth in the pharmerging markets?

Pharmerging markets are driven by increasing healthcare spending, a growing middle class, and expanding access to healthcare services[1].

Sources

  1. IQVIA Quarterly Pharmaceutical Market Outlook - November 2023
  2. Correlation Between Changes in Brand-Name Drug Prices and Out-of-Pocket Spending
  3. Drug Interdiction and Counter-Drug Activities
  4. Drug Snapshot: Shifting Paradigms in Hematology-Oncology
  5. R [Diatrizoate Meglumine and Diatrizoate Sodium Injection USP]

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