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Last Updated: April 2, 2025

MESNEX Drug Patent Profile


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When do Mesnex patents expire, and what generic alternatives are available?

Mesnex is a drug marketed by Baxter Hlthcare and is included in two NDAs.

The generic ingredient in MESNEX is mesna. There are ten drug master file entries for this compound. Seven suppliers are listed for this compound. Additional details are available on the mesna profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Mesnex

A generic version of MESNEX was approved as mesna by FRESENIUS KABI USA on April 26th, 2001.

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Summary for MESNEX
Drug patent expirations by year for MESNEX
Drug Prices for MESNEX

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Recent Clinical Trials for MESNEX

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
James Isaacs, MDPhase 1
Markus MaparaPhase 1/Phase 2
ITB-Med LLCPhase 1/Phase 2

See all MESNEX clinical trials

Pharmacology for MESNEX

US Patents and Regulatory Information for MESNEX

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Baxter Hlthcare MESNEX mesna INJECTABLE;INTRAVENOUS 019884-001 Dec 30, 1988 AP RX Yes Yes ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Baxter Hlthcare MESNEX mesna TABLET;ORAL 020855-001 Mar 21, 2002 AB RX Yes Yes ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 2 of 2 entries

Expired US Patents for MESNEX

ApplicantTradenameGeneric NameDosageNDAApproval DatePatent No.Patent Expiration
Baxter Hlthcare MESNEX mesna INJECTABLE;INTRAVENOUS 019884-001 Dec 30, 1988 ⤷  Try for Free ⤷  Try for Free
Baxter Hlthcare MESNEX mesna INJECTABLE;INTRAVENOUS 019884-001 Dec 30, 1988 ⤷  Try for Free ⤷  Try for Free
Baxter Hlthcare MESNEX mesna TABLET;ORAL 020855-001 Mar 21, 2002 ⤷  Try for Free ⤷  Try for Free
Baxter Hlthcare MESNEX mesna TABLET;ORAL 020855-001 Mar 21, 2002 ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>Patent No.>Patent Expiration
Showing 1 to 4 of 4 entries

International Patents for MESNEX

See the table below for patents covering MESNEX around the world.

CountryPatent NumberTitleEstimated Expiration
Bulgaria 60851 ⤷  Try for Free
Hungary T59317 ⤷  Try for Free
Hungary 9302837 ⤷  Try for Free
Ireland 65373 A tablet and granulate containing mesna as active substance ⤷  Try for Free
Japan S54101432 DETOXICATION OF CELL PROPAGATION CONTROLLING AGENT ⤷  Try for Free
Mexico 174407 TABLETA Y GRANULADO QUE CONTIENEN MESNA COMO SU STANCIA ACTIVA ⤷  Try for Free
Spain 2063412 ⤷  Try for Free
>Country>Patent Number>Title>Estimated Expiration
Showing 1 to 7 of 7 entries

Market Dynamics and Financial Trajectory for MESNEX

Introduction to MESNEX

MESNEX, also known as mesna, is a crucial drug in the antineoplastic detoxifying agents class, primarily used for the prevention of hemorrhagic cystitis, a common side effect of certain chemotherapy agents like ifosfamide and cyclophosphamide.

Market Growth Drivers

Increasing Incidence of Cancer

The global MESNEX market is driven significantly by the rising incidence of cancer cases. According to estimates, the number of cancer cases was approximately 1,735,350 in 2018 and is expected to increase by 3% annually. This surge in cancer cases has led to an increased demand for chemotherapy treatments, which in turn drives the demand for MESNEX[1].

Advancements in Chemotherapy

The evolution and rapid progress in chemotherapy practices are another key factor boosting the market growth. As chemotherapy becomes more prevalent and sophisticated, the need for protective agents like MESNEX to mitigate side effects such as hemorrhagic cystitis increases[1].

Clinical Research and FDA Approvals

Ongoing clinical research and increasing FDA approvals for new therapies are also accelerating the growth of the MESNEX market. These approvals open up new treatment avenues and expand the use of MESNEX in various medical applications[1].

Market Segmentation

By Type

The MESNEX market is segmented into two main types: oral tablets and injectable solutions. The injectable solution is more commonly used due to its rapid action and efficacy in preventing hemorrhagic cystitis[1][4].

By Application

The market is further segmented by application into hospital pharmacies, retail pharmacies, and online pharmacies. Hospital pharmacies dominate this segment due to the frequent use of MESNEX in hospital settings for chemotherapy patients[1][4].

By Region

Geographically, the market is divided into North America, Europe, Asia-Pacific, and the rest of the world. North America and Europe are significant markets due to their advanced healthcare systems and high incidence of cancer[1][4].

Financial Trajectory

Market Size and Forecast

The global MESNEX market is expected to grow at a significant CAGR during the forecast period (2021-2031). The market size is anticipated to increase from its current valuation to a substantial figure by 2031, driven by the factors mentioned above[1][4].

Pricing and Cost

The cost of MESNEX varies depending on the form and dosage. For instance, the injectable solution (100 mg/mL) can cost around $36 for a supply of 10 milliliters, while the oral tablet (400 mg) can cost approximately $837.06 for 10 tablets. Generic versions are also available, which can reduce the cost significantly[2].

Competitive Landscape

The MESNEX market is competitive, with several key players such as Sagent Pharmaceuticals, Inc., Fresenius SE & Co. KGaA, Baxter International Inc., Mylan, Hikma Pharmaceuticals, and Teva Pharmaceutical, among others. These companies are involved in continuous research and development to improve the efficacy and availability of MESNEX[1][4].

Market Outlook

Growth Prospects

The market outlook for MESNEX is positive, driven by the increasing demand for chemotherapy agents and the expanding use of MESNEX in new treatment protocols. The rising incidence of cancer and advancements in chemotherapy practices are expected to sustain the growth of the market[1][3].

Challenges and Opportunities

Despite the growth prospects, the market faces challenges such as adverse reactions associated with MESNEX, particularly when used in combination with other chemotherapy agents. However, ongoing clinical research and the potential for new applications present significant opportunities for market expansion[5].

Key Statistics

  • Cancer Incidence: Estimated to grow by 3% annually, with 1,735,350 cases in 2018[1].
  • Market Growth: Expected to grow at a CAGR of 3 to 5% from 2023 to 2031[4].
  • Market Size: Projected to reach a significant figure by 2031 from its current valuation[4].
  • Pricing: Injectable solution costs around $36 for 10 milliliters, and oral tablets cost approximately $837.06 for 10 tablets[2].

Quotes from Industry Experts

"The increasing prevalence of various cancers, particularly lung, testicular, and ovarian cancers, is a primary driver for the chemotherapy market, which in turn drives the demand for protective agents like MESNEX." - Industry Analyst[3].

Illustrative Statistics

  • Cancer Cases: The World Health Organization estimates that cancer incidences will rise significantly due to an aging population and lifestyle changes[3].
  • Chemotherapy Market: The cisplatin market, another key chemotherapy agent, is projected to grow from USD 14.2 Billion in 2023 to USD 25.6 Billion by 2031, indicating a robust growth in the chemotherapy sector[3].

Adverse Reactions and Safety

MESNEX is associated with several adverse reactions, including headache, injection site reactions, flushing, dizziness, nausea, and vomiting. It is crucial to monitor patients for these side effects, especially when used in combination with other chemotherapy agents[5].

Key Takeaways

  • The MESNEX market is driven by the increasing incidence of cancer and advancements in chemotherapy.
  • The market is segmented by type (oral and injectable) and application (hospital, retail, and online pharmacies).
  • Key players include Sagent Pharmaceuticals, Fresenius SE & Co. KGaA, and Baxter International Inc.
  • The market is expected to grow significantly from 2023 to 2031.
  • Adverse reactions and safety concerns are critical factors to consider in the use of MESNEX.

FAQs

What is MESNEX used for?

MESNEX is used to prevent hemorrhagic cystitis, a common side effect of certain chemotherapy agents like ifosfamide and cyclophosphamide.

What are the common forms of MESNEX?

MESNEX is available in two main forms: oral tablets and injectable solutions.

How much does MESNEX cost?

The cost of MESNEX varies; the injectable solution (100 mg/mL) can cost around $36 for 10 milliliters, and the oral tablet (400 mg) can cost approximately $837.06 for 10 tablets.

What are the key drivers of the MESNEX market?

The key drivers include the increasing incidence of cancer, advancements in chemotherapy practices, and ongoing clinical research.

What are the potential challenges for the MESNEX market?

The market faces challenges such as adverse reactions associated with MESNEX, particularly when used in combination with other chemotherapy agents.

Sources

  1. Global Mesna (Mesnex) Market 2021 Size, Growth Analysis Report - OMRGlobal
  2. Mesnex Prices, Coupons, Copay Cards & Patient Assistance - Drugs.com
  3. Cisplatin Market Size, Scope, Growth, Trends and Forecast - Verified Market Research
  4. Global mesna mesnex market size and forecast - Market Research Intellect
  5. FULL PRESCRIBING INFORMATION - FDA[5]

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