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Last Updated: December 22, 2024

METHOTREXATE LPF Drug Patent Profile


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When do Methotrexate Lpf patents expire, and when can generic versions of Methotrexate Lpf launch?

Methotrexate Lpf is a drug marketed by Hospira and is included in one NDA.

The generic ingredient in METHOTREXATE LPF is methotrexate sodium. There are twenty drug master file entries for this compound. Twenty-eight suppliers are listed for this compound. Additional details are available on the methotrexate sodium profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Methotrexate Lpf

A generic version of METHOTREXATE LPF was approved as methotrexate sodium by HIKMA on September 16th, 1986.

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Summary for METHOTREXATE LPF
Drug patent expirations by year for METHOTREXATE LPF
Recent Clinical Trials for METHOTREXATE LPF

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Alexion Pharmaceuticals, Inc.Phase 4
Syndax PharmaceuticalsPhase 1
University of California, Los AngelesPhase 1

See all METHOTREXATE LPF clinical trials

Pharmacology for METHOTREXATE LPF

US Patents and Regulatory Information for METHOTREXATE LPF

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Hospira METHOTREXATE LPF methotrexate sodium INJECTABLE;INJECTION 011719-007 Mar 31, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

METHOTREXATE LPF Market Analysis and Financial Projection Experimental

Methotrexate Drug Market: Dynamics and Financial Trajectory

Introduction

Methotrexate, a widely used medication for treating various inflammatory diseases and cancers, is experiencing significant growth in the global market. Here, we will delve into the market dynamics and financial trajectory of methotrexate, highlighting key trends, drivers, and projections.

Market Size and Growth

The methotrexate drug market is valued at USD 584.09 million in 2024 and is expected to exceed USD 846.99 million by 2037, growing at a Compound Annual Growth Rate (CAGR) of over 2.9% during the forecast period of 2025-2037[1].

Alternatively, another forecast suggests that the market will grow at a CAGR of 5.5% from 2024 to 2034, reaching a valuation of USD 1,058 million by 2034[3].

Drivers of Growth

Increasing Prevalence of Autoimmune Diseases

The rising prevalence of autoimmune diseases such as rheumatoid arthritis, juvenile rheumatoid arthritis, and lupus is a significant driver of the methotrexate market. Methotrexate is the recommended first-line treatment for rheumatoid arthritis, with about 60% of patients with this condition currently taking the drug[1].

Growing Healthcare Expenditure

Expanding healthcare expenditure, particularly in regions like the United States, is anticipated to drive demand for methotrexate. Investments in healthcare infrastructure and the shift toward value-based care are contributing factors[3].

Cancer Treatment

Methotrexate is also used as a chemotherapy agent for various cancers. The increasing number of cancer patients seeking treatment at hospitals is expected to boost the market, with the hospital segment projected to grow at the highest CAGR of 3.3% during the forecast period[1].

Market Segmentation

By Indication

  • Rheumatoid Arthritis: This segment is expected to register a significant CAGR due to the high usage of methotrexate as a first-line treatment. The American College of Rheumatology recommends methotrexate for rheumatoid arthritis, contributing to its dominance in this segment[1][3].

  • Cancer: Methotrexate's role in chemotherapy for various cancers, including leukemia, also drives market growth. The increasing prevalence of cancer cases, such as the 1.9 million new cancer cases diagnosed in the United States in 2022, supports this trend[3].

By Distribution Channel

  • Hospitals: The hospital segment is expected to garner a significant share due to the increasing influx of patients with target diseases. Hospitals are primary centers for chemotherapy and treatment of autoimmune diseases, making them key distribution channels[1].

  • Specialty Clinics: These clinics are also expected to grow at a significant rate, driven by the specialized care they provide for patients with chronic conditions[1].

Regional Analysis

North America

North America dominates the global methotrexate market due to high healthcare expenditure and extensive research and development activities. The region is expected to grow at a CAGR of 5.7% from 2024 to 2034[3].

Europe

Europe accounts for the second-largest market share, driven by increased research and development and the presence of advanced medical facilities. The region is also expected to grow at a CAGR of 5.7% during the same period[3].

Asia-Pacific

The Asia-Pacific region is anticipated to show rapid and lucrative growth due to increased technological advancements, growing healthcare expenditure, and rising awareness programs. Countries like China and Japan are expected to register CAGRs of 5.9% and 7.0%, respectively, during the forecast period[3].

Competitive Landscape

The methotrexate market is competitive, with several players investing heavily in research and development to improve existing products and develop new ones. The entry of new players is expected to intensify competition, driving innovation and better patient outcomes[3].

Recent Developments

Companies are focusing on innovating new drugs to reduce the challenges faced by patients. For instance, the combination of methotrexate with other treatments, such as certolizumab pegol, has shown sustained efficacy and safety in long-term treatment for rheumatoid arthritis patients[4].

Financial Projections

  • Market Value: The methotrexate drug market is projected to increase from USD 621.3 million in 2024 to USD 1,058 million by 2034, representing a significant financial growth trajectory[3].

  • CAGR: The market is expected to grow at a CAGR of 5.5% from 2024 to 2034, indicating steady and consistent financial growth[3].

  • Segment Growth: The hospital segment, in particular, is expected to grow at a CAGR of 3.3% during the forecast period, contributing significantly to the overall financial trajectory[1].

Challenges and Opportunities

Affordability and Access

Despite the growth, there are concerns about the affordability and access to methotrexate, especially in regions with limited healthcare resources. This presents both a challenge and an opportunity for manufacturers to develop more affordable and accessible treatment options[2].

Integrative Medicine

The rising interest in integrative medicine in the United States and other regions creates lucrative opportunities for the methotrexate market. Combining traditional Western medicine with complementary therapies can enhance treatment outcomes and patient satisfaction[3].

Key Takeaways

  • The methotrexate drug market is expected to grow significantly, driven by the increasing prevalence of autoimmune diseases and cancer.
  • The market is valued at USD 584.09 million in 2024 and is projected to reach USD 1,058 million by 2034.
  • North America and Europe are dominant regions, with Asia-Pacific showing rapid growth.
  • Hospitals and specialty clinics are key distribution channels.
  • The market faces challenges related to affordability but also presents opportunities in integrative medicine and innovative product development.

FAQs

What is the current market size of the methotrexate drug market?

The methotrexate drug market was valued at USD 584.09 million in 2024[1].

What is the projected growth rate of the methotrexate market?

The market is expected to grow at a CAGR of 5.5% from 2024 to 2034[3].

Which segment dominates the methotrexate market?

The rheumatoid arthritis segment dominates the methotrexate market due to its widespread use as a first-line treatment[1][3].

What are the key drivers of the methotrexate market?

Key drivers include the increasing prevalence of autoimmune diseases, growing healthcare expenditure, and the use of methotrexate in cancer treatment[1][3].

Which regions are expected to show significant growth in the methotrexate market?

North America, Europe, and the Asia-Pacific region are expected to show significant growth, with the Asia-Pacific region showing the most rapid and lucrative growth[3].

Sources

  1. Research Nester: Methotrexate Drugs Market Size & Share, Forecast Report 2037.
  2. National Bureau of Economic Research: Estimating the Financial Impact of Gene Therapy in the US.
  3. Future Market Insights: Methotrexate Drug Market Size, Share, Trends & Forecast by 2034.
  4. Science.gov: Receiving long-term methotrexate: Topics by Science.gov.
  5. Data Bridge Market Research: Methotrexate Injection Market Size, Value & Opportunities By 2030.

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