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Last Updated: December 22, 2024

NEPTAZANE Drug Patent Profile


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When do Neptazane patents expire, and when can generic versions of Neptazane launch?

Neptazane is a drug marketed by Lederle and is included in one NDA.

The generic ingredient in NEPTAZANE is methazolamide. There are seven drug master file entries for this compound. Twelve suppliers are listed for this compound. Additional details are available on the methazolamide profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Neptazane

A generic version of NEPTAZANE was approved as methazolamide by ANI PHARMS on June 30th, 1993.

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Summary for NEPTAZANE
Drug patent expirations by year for NEPTAZANE
Recent Clinical Trials for NEPTAZANE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
National Eye Institute (NEI)Phase 3
University of MiamiPhase 3
University of Colorado, DenverPhase 1/Phase 2

See all NEPTAZANE clinical trials

US Patents and Regulatory Information for NEPTAZANE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Lederle NEPTAZANE methazolamide TABLET;ORAL 011721-002 Nov 25, 1991 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Lederle NEPTAZANE methazolamide TABLET;ORAL 011721-001 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

NEPTAZANE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Neptazane (Methazolamide)

Overview of Neptazane (Methazolamide)

Neptazane, known generically as methazolamide, is a carbonic anhydrase inhibitor used primarily to treat glaucoma by reducing intraocular pressure. It is also utilized as a diuretic in cases of congestive heart failure and for treating certain types of seizures and altitude sickness[2].

Market Size and Growth

The methazolamide market has been experiencing significant growth, driven by several key factors:

  • Current Market Size: The methazolamide market was valued at USD 9,269.8 million in 2023[1].
  • Forecasted Growth: It is estimated to reach USD 16,781.2 million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 6.9% from 2024 to 2032[1].

Regional Market Dynamics

The market dynamics of methazolamide vary across different regions:

  • North America and Europe: These regions are prominent due to their advanced healthcare infrastructure, high prevalence of glaucoma, and robust pharmaceutical industries. Extensive research and development activities, along with the presence of key pharmaceutical companies and well-established distribution networks, contribute to the market growth in these areas[1].
  • Asia-Pacific: This region is emerging as a significant market driven by increasing healthcare expenditure, improving access to healthcare services, and rising awareness about ocular health. The large population base, aging population, and changing lifestyles are key factors contributing to the expanding market opportunities[1].
  • Latin America and Middle East & Africa: These regions are experiencing gradual growth supported by improving healthcare infrastructure and increasing initiatives to combat eye diseases[1].

Key Drivers of Market Growth

Several factors are driving the growth of the methazolamide market:

  • Increasing Prevalence of Glaucoma: The rapidly increasing incidence of glaucoma worldwide, particularly among the aging population, is a major driver. Glaucoma is a significant cause of blindness, and effective treatments like methazolamide are in high demand[4].
  • Advances in Pharmaceutical Technologies: Improvements in drug formulations and delivery systems, such as modified release formulations, are enhancing the therapeutic efficiency of methazolamide while reducing undesirable side effects[4].
  • Growing Healthcare Expenditure: Increasing healthcare expenditure and improving access to healthcare services, especially in emerging markets, are contributing to the market growth[1].

Market Segmentation

The methazolamide market is segmented based on several criteria:

  • By Product Type: Oral tablets hold the maximum share of the methazolamide market, given their systemic therapy benefits and ease of administration[1].
  • By Application: The primary application is in the treatment of glaucoma, but it is also used as a diuretic and for other conditions like seizures and altitude sickness[2].
  • By Geography: The market is analyzed across regions such as North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa[1].

Key Players and Competitive Landscape

The methazolamide market is competitive with several key players:

  • Major Companies: Daicel Chiral Technologies (India) Pvt. Ltd., SimSon Pharma Limited, Merck KGaA, Cambridge Bioscience Limited, Selleck Chemicals, Aspen API, Biophore India Pharmaceuticals Pvt, Minakem, ChemSrc, Midas Pharma GmbH, Novartis AG, and Teva Pharmaceutical Industries Ltd. are some of the prominent companies operating in this market[1].

Financial Trajectory

The financial trajectory of the methazolamide market is promising:

  • Capital Expenditure and Operational Expenditure: Setting up a methazolamide manufacturing plant involves significant capital expenditure (CapEx) and operational expenditure (OpEx). The report provides detailed insights into project economics, including income projections, taxation, depreciation, and profitability analysis[4].
  • Profitability Analysis: The report covers a detailed analysis of the project economics, including expected Return on Investment (ROI), Net Present Value (NPV), payback period, and sensitivity analysis. This helps in understanding the financial viability of investing in a methazolamide manufacturing plant[4].

Regulatory and Approval Aspects

The setup and operation of a methazolamide manufacturing plant require adherence to various regulatory procedures and approvals:

  • Regulatory Procedures: The report provides information on the necessary certifications, financial assistance, and regulatory approvals required for setting up a methazolamide manufacturing plant[4].

Side Effects and Patient Compliance

Minimizing side effects is crucial for patient compliance and overall quality of life:

  • Common Side Effects: Neptazane can cause side effects such as nausea, vomiting, loss of appetite, diarrhea, numbness or tingling, drowsiness, and hearing problems. Serious side effects include allergic reactions, blood cell disorders, liver problems, and signs of metabolic acidosis[2].
  • Modified Formulations: Pharmaceutical companies are developing modified release formulations to maintain therapeutic efficiency while reducing undesirable effects[4].

Future Outlook

The future outlook for the methazolamide market is positive, driven by increasing demand for effective glaucoma treatments and advancements in pharmaceutical technologies.

"The global methazolamide market is witnessing significant growth, mainly because of the rapidly increasing incidence of glaucoma worldwide. Along with the aging population, the number of individuals at risk for glaucoma is increasing which underscores the need for effective treatment solutions such as methazolamide"[4].

Key Takeaways

  • The methazolamide market is projected to grow significantly, driven by the increasing prevalence of glaucoma and advancements in pharmaceutical technologies.
  • North America and Europe are leading regions, while the Asia-Pacific region is emerging as a significant market.
  • Key players are focusing on developing modified release formulations to reduce side effects.
  • The market is segmented by product type, application, and geography.
  • Regulatory compliance and financial analysis are crucial for setting up a methazolamide manufacturing plant.

FAQs

What is Neptazane (methazolamide) used for?

Neptazane (methazolamide) is used to lower intraocular pressure in people with certain types of glaucoma. It is also used as a diuretic in cases of congestive heart failure and for treating certain types of seizures and altitude sickness[2].

What is the current market size of methazolamide?

The methazolamide market was valued at USD 9,269.8 million in 2023[1].

What is the forecasted growth rate of the methazolamide market?

The methazolamide market is estimated to grow at a CAGR of 6.9% from 2024 to 2032[1].

Which regions are leading the methazolamide market?

North America and Europe are the leading regions, while the Asia-Pacific region is emerging as a significant market[1].

What are the common side effects of Neptazane (methazolamide)?

Common side effects include nausea, vomiting, loss of appetite, diarrhea, numbness or tingling, drowsiness, and hearing problems. Serious side effects can include allergic reactions, blood cell disorders, and liver problems[2].

Who are the key players in the methazolamide market?

Key players include Daicel Chiral Technologies (India) Pvt. Ltd., SimSon Pharma Limited, Merck KGaA, Cambridge Bioscience Limited, Selleck Chemicals, Aspen API, Biophore India Pharmaceuticals Pvt, Minakem, ChemSrc, Midas Pharma GmbH, Novartis AG, and Teva Pharmaceutical Industries Ltd.[1].

Sources

  1. Acumen Research and Consulting, "Methazolamide Market Size, Share, Trends | Forecast 2032".
  2. Drugs.com, "Neptazane Uses, Side Effects & Warnings".
  3. IMARC Group, "Methazolamide (Neptazane) Manufacturing Plant Report 2024: Industry Trends, Plant Setup, Machinery, Raw Materials, Investment Opportunities, Cost and Revenue".
  4. IMARC Group, "Methazolamide (Neptazane) Manufacturing Plant Report 2024".

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