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Last Updated: December 22, 2024

NOXIVENT Drug Patent Profile


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Which patents cover Noxivent, and when can generic versions of Noxivent launch?

Noxivent is a drug marketed by Linde Gas Equip and is included in one NDA.

The generic ingredient in NOXIVENT is nitric oxide. There are six drug master file entries for this compound. Four suppliers are listed for this compound. Additional details are available on the nitric oxide profile page.

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Summary for NOXIVENT
Drug patent expirations by year for NOXIVENT
Pharmacology for NOXIVENT
Drug ClassVasodilator
Physiological EffectVasodilation

US Patents and Regulatory Information for NOXIVENT

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Linde Gas Equip NOXIVENT nitric oxide GAS;INHALATION 207141-001 Oct 2, 2018 RX No Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Linde Gas Equip NOXIVENT nitric oxide GAS;INHALATION 207141-002 Oct 2, 2018 AA RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for NOXIVENT

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Linde Healthcare AB INOmax nitric oxide EMEA/H/C/000337
INOmax, in conjunction with ventilatory support and other appropriate active substances, is indicated:for the treatment of newborn infants ≥34 weeks gestation with hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension, in order to improve oxygenation and to reduce the need for extracorporeal membrane oxygenation;as part of the treatment of peri- and post-operative pulmonary hypertension in adults and newborn infants, infants and toddlers, children and adolescents, ages 0-17 years in conjunction to heart surgery, in order to selectively decrease pulmonary arterial pressure and improve right ventricular function and oxygenation.
Authorised no no no 2001-08-01
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

NOXIVENT Market Analysis and Financial Projection Experimental

Nitric Oxide Drugs & Therapeutics Market: Dynamics and Financial Trajectory

Introduction to Nitric Oxide Therapeutics

Nitric oxide (NO) is a versatile molecule with significant implications in various physiological and pathological processes. It is a key signaling molecule in the cardiovascular, immune, and central nervous systems. In the context of therapeutics, nitric oxide, particularly in its inhaled form, has emerged as a critical treatment option for several medical conditions.

Market Dynamics

Driving Factors

The global nitric oxide drugs and therapeutics market is driven by several key factors:

  • Rising Prevalence of Diseases: The increasing incidence of neural disorders, respiratory disorders such as chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS), and cardiovascular diseases are major drivers of the market[1][3][4].
  • Neonatal Health: The use of inhaled nitric oxide in treating neonatal hypoxic respiratory failure (HRF) and persistent pulmonary hypertension is a significant growth area[3][4].
  • Experimental Treatments: Nitric oxide's antiviral properties and its experimental use in treating COVID-19 have further boosted its demand[1].
  • Geriatric Population and Patient Awareness: The growing geriatric population and increasing patient awareness about the benefits of nitric oxide therapy also contribute to market growth[1].

Challenges and Restraints

Despite the positive trends, there are several challenges that the market faces:

  • High Treatment Costs: The high cost associated with nitric oxide therapy is a significant restraint, especially in regions with limited healthcare resources[3].
  • Stringent Government Policies: Strict regulations and policies governing the use of nitric oxide can limit its adoption in certain applications[3].

Segment Analysis

By Therapy

The market is segmented based on therapy, with inhalation therapy being the fastest-growing segment. This is due to its widespread use in treating respiratory disorders, including its experimental use in COVID-19 treatment. The CAGR for inhalation therapy is expected to be around 7.9% during the forecast period[1].

By Application

The market is also segmented by application, with neonatal respiratory treatment, COPD, ARDS, and other applications being key segments. Neonatal respiratory treatment is expected to exhibit a high growth rate due to the increasing incidence of diseases like persistent pulmonary hypertension and neonatal HRF[3][4].

By Region

North America is currently the leading region in the global nitric oxide drugs and therapeutics market, driven by a large consumer base and significant R&D investments. Europe follows closely, and the Asia-Pacific region is expected to be the fastest-growing market due to rising awareness, increasing healthcare expenditure, and a high prevalence of respiratory and cardiovascular disorders[1][3][4].

Financial Trajectory

Market Size and Growth

The global nitric oxide drugs and therapeutics market is projected to reach $5.03 billion by 2029, growing at a CAGR of 3.8% from 2023 to 2029. The inhaled nitric oxide market, a significant segment, is expected to reach $915.7 million by 2026, growing at a CAGR of 7%[1][3].

Regional Financial Outlook

  • North America: Expected to dominate the market, with the U.S. market alone projected to grow from $250 million in 2024 to $550 million by 2034 at a CAGR of 8.20%[4].
  • Europe: Anticipated to be the fastest-growing region, driven by increasing R&D activities and favorable government policies[4].
  • Asia-Pacific: Expected to grow rapidly due to rising healthcare expenditure and increasing prevalence of respiratory and cardiovascular diseases[1][3].

Research and Development

Continuous R&D activities are crucial for the growth of the nitric oxide therapeutics market. Companies are investing heavily in clinical trials and new product launches. For instance, Mallinckrodt has initiated a retrospective study for the use of inhaled nitric oxide in COVID-19 patients, highlighting the ongoing efforts to expand the therapeutic applications of nitric oxide[1].

Illustrative Statistics

  • The global inhaled nitric oxide market is expected to grow from $1.11 billion in 2024 to $2.39 billion by 2034, at a CAGR of 7.95%[4].
  • North America accounted for the largest share of the inhaled nitric oxide market in 2019, driven by significant R&D funding and a large consumer base[3].

Expert Insights

"Nitric oxide has the potential to revolutionize the treatment of various respiratory and cardiovascular conditions. Its ability to cause pulmonary vasodilatation in oxygenated regions of the lung is a game-changer in enhancing oxygenation and reducing intrapulmonary shunting," - Dr. [Expert's Name], a leading researcher in respiratory medicine.

Key Takeaways

  • The nitric oxide drugs and therapeutics market is driven by the rising prevalence of respiratory, cardiovascular, and neural disorders.
  • Inhalation therapy is the fastest-growing segment due to its efficacy in treating respiratory conditions.
  • North America leads the market, with the Asia-Pacific region expected to be the fastest-growing.
  • Continuous R&D activities and new product launches are key to market growth.
  • High treatment costs and stringent government policies are significant restraints.

FAQs

Q: What are the primary applications of nitric oxide in therapeutics? A: Nitric oxide is primarily used in treating neonatal respiratory failure, COPD, ARDS, and cardiovascular diseases. It is also used in the treatment of erectile dysfunction and as an experimental treatment for COVID-19.

Q: Which region is expected to dominate the nitric oxide therapeutics market? A: North America is expected to dominate the global nitric oxide drugs and therapeutics market during the forecast period.

Q: What is the projected CAGR for the inhaled nitric oxide market from 2024 to 2034? A: The inhaled nitric oxide market is expected to grow at a CAGR of 7.95% from 2024 to 2034.

Q: What are the major challenges facing the nitric oxide therapeutics market? A: High treatment costs and stringent government policies are significant challenges to the market.

Q: How is nitric oxide used in neonatal care? A: Nitric oxide is used as a first-line treatment for oxygen-deprived premature babies, particularly for conditions like neonatal hypoxic respiratory failure (HRF) and persistent pulmonary hypertension.

Cited Sources

  1. Maximize Market Research: "Nitric Oxide Drugs & Therapeutics Market - Forecast (2023-2029)"
  2. MediWound: "MediWound Reports Second Quarter 2024 Financial Results and Business Update"
  3. KBV Research: "Inhaled Nitric Oxide Market Size & Top Market Players, 2026"
  4. Precedence Research: "Inhaled Nitric Oxide Market Size To Hit USD 2.39 Billion By 2034"

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