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Last Updated: December 25, 2024

NUPRIN Drug Patent Profile


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Which patents cover Nuprin, and what generic alternatives are available?

Nuprin is a drug marketed by Bristol Myers and J And J Consumer Inc and is included in three NDAs.

The generic ingredient in NUPRIN is ibuprofen. There are sixty-four drug master file entries for this compound. Two hundred and forty suppliers are listed for this compound. Additional details are available on the ibuprofen profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Nuprin

A generic version of NUPRIN was approved as ibuprofen by STRIDES PHARMA on September 24th, 1986.

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Drug patent expirations by year for NUPRIN
Recent Clinical Trials for NUPRIN

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Alphacait, LLCPhase 2
Haining Health-Coming Biotech Co., Ltd.Phase 2
National Institutes of Health Clinical Center (CC)Phase 1

See all NUPRIN clinical trials

Pharmacology for NUPRIN

US Patents and Regulatory Information for NUPRIN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bristol Myers NUPRIN ibuprofen TABLET;ORAL 072035-001 Feb 16, 1988 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
J And J Consumer Inc NUPRIN ibuprofen TABLET;ORAL 019012-002 Jul 29, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Bristol Myers NUPRIN ibuprofen TABLET;ORAL 072036-001 Feb 16, 1988 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
J And J Consumer Inc NUPRIN ibuprofen TABLET;ORAL 019012-001 May 18, 1984 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for NUPRIN

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Recordati Rare Diseases Pedea ibuprofen EMEA/H/C/000549
Treatment of a haemodynamically significant patent ductus arteriosus in preterm newborn infants less than 34 weeks of gestational age.
Authorised no no no 2004-07-28
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

NUPRIN Market Analysis and Financial Projection Experimental

Non-Steroidal Anti-Inflammatory Drugs Market: The Case of Nuprin

Introduction

Non-steroidal anti-inflammatory drugs (NSAIDs) are a cornerstone in the management of pain, inflammation, and fever. Among these, Nuprin, an ibuprofen-based NSAID, has a fascinating history and market dynamics. Here, we delve into the market dynamics and financial trajectory of Nuprin, as well as the broader NSAIDs market.

Historical Context of Nuprin

Nuprin, once a product of Bristol-Myers Squibb Co., was introduced as a competitor to other popular ibuprofen brands like Advil and Motrin. However, by 2002, Bristol-Myers Squibb decided to exit the highly competitive over-the-counter pain medication market, deeming Nuprin unprofitable[2].

Revival of Nuprin

In a strategic move, Paul Earle Jr. and his company, RiverWestBrands, acquired the rights to the Nuprin brand in 2003. Earle saw potential in positioning Nuprin as a drugstore-owned brand, which led to a partnership with CVS. This strategy allowed Nuprin to be priced between generic ibuprofen and other name-brand products, offering consumers a trustworthy yet affordable option[2].

Market Dynamics of NSAIDs

The global NSAIDs market is driven by several key factors:

Prevalence of Arthritis

Arthritis remains the leading target for NSAIDs, capturing a significant market share. In the U.S., approximately 53.2 million adults suffer from arthritis, with women more affected than men[1].

Convenience and Accessibility

The oral route of administration dominates the market, accounting for 56% of the share, due to its convenience. Retail pharmacies, such as CVS, lead the market, holding a commanding 46% share[1].

Aging Population

The global population of older people is projected to more than double from 761 million in 2021 to 1.6 billion by 2050, leading to increased demand for NSAIDs due to higher incidence of bone problems[1].

Preference Over Opioids

NSAIDs are often preferred over opioid medications due to their lower risk of addiction and fewer side effects. This preference has been exacerbated by concerns over opioid addiction and abuse[1].

Financial Trajectory of the NSAIDs Market

The global NSAIDs market is expected to grow significantly:

Current Market Size

In 2023, the NSAIDs market was valued at approximately USD 21.01 billion[1].

Projected Growth

By 2031, the market is projected to reach USD 31.03 billion, and by 2032, it is expected to be worth around USD 33.55 billion[1][4].

Regional Dominance

North America holds a dominant share in the global NSAIDs market, driven by the high prevalence of arthritis and the strategic presence of major manufacturers[4].

Nuprin's Place in the Market

Nuprin, now part of CVS's product lineup, benefits from the overall growth trends in the NSAIDs market:

Brand Revival

By being repositioned as a drugstore-owned brand, Nuprin has found a niche between generic and name-brand products, appealing to consumers seeking a balance between cost and trustworthiness[2].

Product Diversification

CVS uses the Nuprin label on more than 12 health products, including decongestant sprays, arthritis patches, and muscle and joint creams, further expanding its market reach[2].

Challenges and Considerations

While Nuprin and the broader NSAIDs market are growing, there are several challenges to consider:

Side Effects and Risks

NSAIDs, including Nuprin, come with risks such as increased cardiovascular thrombotic events, myocardial infarction, and serious gastrointestinal adverse events. These risks are particularly significant for patients with cardiovascular disease or those who are elderly[5].

Regulatory Environment

The market is subject to regulatory scrutiny, with ongoing research and monitoring of NSAIDs' safety profiles. This can impact market dynamics and consumer confidence[5].

Technological Advancements

Advancements in drug delivery technologies, such as topical and sustained-release formulations, have expanded the options available for pain management. These innovations cater to diverse patient needs and preferences, further driving the market growth[1].

Key Takeaways

  • The global NSAIDs market is driven by the rising prevalence of arthritis, aging populations, and preference over opioids.
  • Nuprin, revived by RiverWestBrands and partnered with CVS, has found a niche in the market by offering a balance between cost and trustworthiness.
  • The market is expected to grow significantly, reaching USD 33.55 billion by 2032.
  • Despite growth, the market faces challenges related to side effects and regulatory scrutiny.

FAQs

What is Nuprin?

Nuprin is an ibuprofen-based non-steroidal anti-inflammatory drug (NSAID) that was originally marketed by Bristol-Myers Squibb Co. and later revived by RiverWestBrands.

Why did Bristol-Myers Squibb stop selling Nuprin?

Bristol-Myers Squibb stopped selling Nuprin due to the high competition in the over-the-counter pain medication market from brands like Advil and Motrin.

How was Nuprin revived?

Nuprin was revived by Paul Earle Jr. and his company, RiverWestBrands, which acquired the rights to the brand and partnered with CVS to reposition it as a drugstore-owned brand.

What are the key drivers of the NSAIDs market?

The key drivers include the rising prevalence of arthritis, aging populations, and the preference for NSAIDs over opioids due to their lower risk of addiction and fewer side effects.

What are the potential risks associated with Nuprin and other NSAIDs?

NSAIDs, including Nuprin, can cause serious cardiovascular thrombotic events, myocardial infarction, and gastrointestinal adverse events, particularly in patients with cardiovascular disease or those who are elderly.

How is the NSAIDs market expected to grow in the future?

The global NSAIDs market is expected to grow from USD 21.01 billion in 2023 to around USD 33.55 billion by 2032, driven by increasing demand and technological advancements.

Sources

  1. GlobeNewswire: Non-Steroidal Anti-Inflammatory Drugs Market Size to Worth USD 33.55 Bn by 2032.
  2. Law.com: Bringing Back the Dead.
  3. Market.us: Pain Management Drugs Market Size | CAGR Of 4.2%.
  4. Fortune Business Insights: Non-steroidal Anti-Inflammatory Drugs [NSAIDs] Market Size By 2032.
  5. Drugs.com: Nuprin Advanced Patient Information.

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