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Last Updated: December 22, 2024

PARAFLEX Drug Patent Profile


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Which patents cover Paraflex, and when can generic versions of Paraflex launch?

Paraflex is a drug marketed by Ortho Mcneil Pharm and is included in one NDA.

The generic ingredient in PARAFLEX is chlorzoxazone. There are sixteen drug master file entries for this compound. Twenty-five suppliers are listed for this compound. Additional details are available on the chlorzoxazone profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Paraflex

A generic version of PARAFLEX was approved as chlorzoxazone by AUROBINDO PHARMA LTD on May 4th, 1988.

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Summary for PARAFLEX
US Patents:0
Applicants:1
NDAs:1
Raw Ingredient (Bulk) Api Vendors: 137
Patent Applications: 3,588
DailyMed Link:PARAFLEX at DailyMed
Drug patent expirations by year for PARAFLEX

US Patents and Regulatory Information for PARAFLEX

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Ortho Mcneil Pharm PARAFLEX chlorzoxazone TABLET;ORAL 011300-003 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

PARAFLEX Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Muscle Relaxant Drugs: A Focus on Paraflex (Chlorzoxazone)

Introduction

The global muscle relaxant drugs market is experiencing significant growth, driven by increasing demand for effective treatments for musculoskeletal disorders. This article will delve into the market dynamics and financial trajectory of muscle relaxant drugs, with a specific focus on Paraflex, a brand name for the drug chlorzoxazone.

Global Muscle Relaxant Drugs Market Overview

The global muscle relaxant drugs market is projected to grow from $4.13 billion in 2022 to $5.79 billion by 2027, with a compound annual growth rate (CAGR) of 6.8% during the forecast period[1].

Key Drivers

  • Rising Geriatric Population: The increasing number of older adults, who are more prone to musculoskeletal disorders, is a significant driver for the market.
  • Product Innovations: Major companies are developing innovative drugs and formulations to sustain their market position.
  • Geographical Expansion: North America dominated the market in 2022, but other regions such as Asia-Pacific and Western Europe are also showing significant growth.

Market Segmentation

The muscle relaxant drugs market is segmented by type, end-user, and geography.

By Type

  • Antispasmodics: Include drugs like chlorzoxazone.
  • Benzodiazepines: Used for their sedative and muscle relaxant properties.
  • Nonbenzodiazepines: Alternative options with fewer side effects.

By End-User

  • Hospitals
  • Homecare
  • Specialty Clinics
  • Other End-Users

Paraflex (Chlorzoxazone) Overview

Clinical Data

Chlorzoxazone, sold under the brand names Paraflex, Lorzone, and Muscol, is a centrally acting muscle relaxant used to treat muscle spasm and associated pain. It acts on the spinal cord by depressing reflexes and is also used for acute pain and tension headaches[4].

Mechanism of Action

The exact mechanism of action of chlorzoxazone is not fully elucidated but is believed to involve the modulation of GABA A and GABA B receptors and voltage-gated calcium channels. It causes general central nervous system depression, which contributes to its muscle relaxant effects[4].

Side Effects and Safety

Common side effects include dizziness, lightheadedness, malaise, nausea, and vomiting. In rare cases, it can cause severe liver dysfunction, although it may also reduce the liver toxicity of acetaminophen through competitive inhibition[4].

Financial Trajectory

Market Size and Growth

While specific financial data for Paraflex is not readily available, the overall muscle relaxant drugs market is expected to grow significantly. The market's projected growth from $4.45 billion in 2023 to $5.79 billion by 2027 indicates a robust financial trajectory for muscle relaxant drugs in general[1].

Competitive Landscape

Major players in the muscle relaxant drugs market, including Pfizer, Amneal Pharmaceuticals, and Merck & Co., are continuously innovating to maintain their market share. For instance, Amneal Pharmaceuticals launched LYVISPAH, a baclofen oral granule, which offers flexible dosing options and is an example of the innovative products driving market growth[1].

Regional Performance

North America dominates the market, but other regions are also contributing to the growth. The global reach and diverse end-user segments ensure a stable financial foundation for muscle relaxant drugs like Paraflex.

Impact of Macro Economic Factors

COVID-19 and Ukraine-Russia War

The COVID-19 pandemic and the Ukraine-Russia war have had varying impacts on the pharmaceutical industry. While these events have disrupted supply chains and affected production, the demand for essential medications like muscle relaxants has remained relatively stable[1].

High Inflation

High inflation can affect the pricing and affordability of drugs, but the essential nature of muscle relaxants tends to mitigate these effects to some extent. Companies often adjust their pricing strategies to balance profitability with patient access[1].

Future Outlook

Innovations and Product Development

The trend towards innovative drug offerings, such as flexible dosing and new formulations, is expected to continue. For example, the launch of LYVISPAH by Amneal Pharmaceuticals highlights the industry's focus on patient convenience and compliance[1].

Regulatory Environment

Regulatory approvals and compliance are crucial for the financial success of any pharmaceutical product. Companies must navigate these regulations to ensure their products remain on the market and continue to generate revenue.

Key Takeaways

  • The global muscle relaxant drugs market is growing, driven by the rising geriatric population and product innovations.
  • Paraflex (chlorzoxazone) is a centrally acting muscle relaxant with a specific mechanism of action and side effect profile.
  • The financial trajectory of muscle relaxant drugs is positive, with a projected market size of $5.79 billion by 2027.
  • Macro economic factors such as COVID-19, the Ukraine-Russia war, and high inflation have had mixed impacts on the market.

FAQs

What is the projected growth rate of the global muscle relaxant drugs market?

The global muscle relaxant drugs market is expected to grow at a CAGR of 6.8% from 2023 to 2027[1].

What are the common side effects of Paraflex (chlorzoxazone)?

Common side effects include dizziness, lightheadedness, malaise, nausea, and vomiting. Rarely, it can cause severe liver dysfunction[4].

Which regions dominate the muscle relaxant drugs market?

North America currently dominates the market, but other regions such as Asia-Pacific and Western Europe are also significant contributors[1].

How do macro economic factors impact the muscle relaxant drugs market?

Macro economic factors like COVID-19, the Ukraine-Russia war, and high inflation can affect supply chains and pricing but generally have a stable impact on the demand for essential medications like muscle relaxants[1].

What are some recent innovations in muscle relaxant drugs?

Recent innovations include the launch of LYVISPAH by Amneal Pharmaceuticals, which offers flexible, customized dosing options for patients with spasticity[1].

Sources

  1. GlobeNewswire: "Pfizer, Amneal Pharmaceuticals, and Merck & Co. Lead the Global Muscle Relaxant Drugs Market with Innovative Drug Offerings and Strong Market Presence."
  2. University of Minnesota Conservancy: "High Risk Medication Regimens and Medication Related Predictors of Hospital Readmission."
  3. PharmaKB: "Financial Analysis of Competitive Drugs."
  4. Wikipedia: "Chlorzoxazone."
  5. CVS Health: "Chlorzoxazone TAB 500mg - Dosage, Side Effects & Drug Information."

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