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Last Updated: April 24, 2025

PFIZER-E Drug Patent Profile


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When do Pfizer-e patents expire, and when can generic versions of Pfizer-e launch?

Pfizer-e is a drug marketed by Pfizer and is included in one NDA.

The generic ingredient in PFIZER-E is erythromycin stearate. There are one hundred and three drug master file entries for this compound. Additional details are available on the erythromycin stearate profile page.

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Summary for PFIZER-E
Drug patent expirations by year for PFIZER-E
Recent Clinical Trials for PFIZER-E

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University Hospital, RouenPhase 3
Dana-Farber Cancer InstitutePhase 2
Prostate Cancer FoundationPhase 2

See all PFIZER-E clinical trials

US Patents and Regulatory Information for PFIZER-E

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Pfizer PFIZER-E erythromycin stearate TABLET;ORAL 061791-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Pfizer PFIZER-E erythromycin stearate TABLET;ORAL 061791-002 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 2 of 2 entries

Market Dynamics and Financial Trajectory of Pfizer

Overview of Pfizer's Current Position

Pfizer, one of the world's largest pharmaceutical companies, has been navigating a complex market landscape, particularly in the post-COVID-19 era. Here’s a detailed look at the market dynamics and financial trajectory of Pfizer.

Market Dynamics

Impact of COVID-19 Products

Pfizer's financial performance has been significantly influenced by its COVID-19 products, including the Comirnaty vaccine and the Paxlovid treatment. However, as the pandemic's impact wanes, the company has seen a decline in revenues from these products. In 2023, Pfizer reported a 41% operational decrease in year-over-year revenues, primarily driven by lower sales of Comirnaty and Paxlovid[1].

Growth in Non-COVID Products

Despite the decline in COVID-related revenues, Pfizer has shown strong growth in its non-COVID products. The company achieved an 8% operational revenue growth in non-COVID products in the fourth quarter of 2023 and a 6% to 8% growth for the full year. This growth was driven by new product launches and the performance of existing products like Abrysvo, the Vyndaqel family, and Eliquis[1].

Recent Product Developments

Pfizer has been actively expanding its product portfolio. For instance, the European Commission granted conditional marketing authorization for Elrexfio (elranatamab-bcmm) in December 2023 for the treatment of adult patients with relapsed and refractory multiple myeloma[1].

Financial Trajectory

Revenue Performance

In 2023, Pfizer reported full-year revenues of $58.5 billion, which was a significant decline from the previous year due to the drop in COVID-19 product sales. However, excluding the contributions from Comirnaty and Paxlovid, revenues grew 7% operationally, driven by new product launches and in-line product growth[1].

For 2024, Pfizer has raised its full-year revenue guidance to a range of $59.5 billion to $62.5 billion, with $5 billion expected from Comirnaty and $3.5 billion from Paxlovid. This adjustment reflects the company's confidence in its non-COVID product portfolio and the impact of recent acquisitions, such as Seagen[2].

Cost Savings and Efficiency

Pfizer is focused on cost savings and efficiency. The company aims to deliver at least $4 billion in annual net cost savings by the end of 2024 through its cost realignment program. Additionally, Pfizer has launched a manufacturing optimization program expected to save $1.5 billion by the end of 2027[2].

Earnings Per Share (EPS)

The company's reported diluted EPS for 2023 was $0.37, down 93% year-over-year, largely due to the decline in COVID-19 product revenues. However, adjusted EPS for the second quarter of 2024 was 60 cents, topping estimates of 46 cents. Pfizer has raised its adjusted EPS guidance for 2024 to between $2.45 and $2.65[2].

Share Performance and Capital Deployment

Pfizer's shares have seen a positive trend in 2024, rising about 9% as of July 2024. The company is committed to enhancing shareholder value through growing dividends, reinvesting in the business, and making share repurchases after de-leveraging the balance sheet. Pfizer has an allowance of $3.3 billion for share repurchases, which it intends to utilize over the next five years[3].

Key Product Performances

Abrysvo

Abrysvo, launched in July 2023 for the older adult indication in the U.S., contributed $515 million in global revenues in the fourth quarter of 2023. This product has been a significant contributor to Pfizer's non-COVID revenue growth[1].

Vyndaqel Family

The Vyndaqel family of products saw a 39% operational revenue increase globally, driven by the strong uptake of the transthyretin amyloid cardiomyopathy (ATTR-CM) indication in the U.S. and developed Europe[1].

Eliquis

Eliquis, an oral anti-coagulant, saw a 9% operational revenue increase globally, driven by continued adoption and market share gains in the non-valvular atrial fibrillation indication in the U.S. and certain European markets[1].

Challenges and Risks

Pipeline Uncertainties

There is no guarantee that Pfizer's pipeline drugs will pass clinical trials, receive approval, or achieve significant sales. This uncertainty poses a risk to the company's future revenue growth[3].

Regulatory Impact

The Inflation Reduction Act could reduce prices of name-brand drugs, potentially impacting Pfizer's revenues if the company is included in future price negotiations[3].

Financial Projections

Revenue Growth

Pfizer expects operational revenue growth of 8% to 10% in 2024, excluding Comirnaty and Paxlovid revenues and including the impact of the Seagen acquisition. This growth is anticipated to be partially offset by the dilutive impact of the Seagen acquisition[1].

Operating Margins

The company anticipates operating margin improvement from its cost realignment activities, which is expected to expand operating margins in 2024 and beyond[1].

Free Cash Flow

Pfizer's free cash flow is projected to improve significantly, with estimates suggesting an increase from $4.8 billion in 2023 to over $10 billion in 2024 and further growth in subsequent years[5].

Conclusion

Pfizer is navigating a transition period, moving from a COVID-19 dominated revenue stream to a more diversified portfolio. The company's focus on cost savings, manufacturing optimization, and the launch of new products positions it for continued growth.

Key Takeaways

  • Diversified Revenue Stream: Pfizer is shifting from COVID-19 product dominance to a more balanced portfolio.
  • Cost Savings: The company aims to achieve significant cost savings through its realignment program.
  • New Product Launches: Recent launches like Abrysvo and the acquisition of Seagen are driving growth.
  • Regulatory Risks: Potential price reductions due to the Inflation Reduction Act pose a risk.
  • Pipeline Uncertainties: Success of pipeline drugs is crucial for future growth.

FAQs

Q: What was the impact of COVID-19 products on Pfizer's 2023 revenues?

A: The decline in COVID-19 product sales led to a 41% operational decrease in year-over-year revenues for Pfizer in 2023[1].

Q: Which non-COVID products contributed significantly to Pfizer's revenue growth in 2023?

A: Products like Abrysvo, the Vyndaqel family, and Eliquis drove the 8% operational revenue growth in non-COVID products[1].

Q: What are Pfizer's financial projections for 2024?

A: Pfizer expects revenues to range from $59.5 billion to $62.5 billion and adjusted EPS between $2.45 and $2.65 in 2024[2].

Q: How is Pfizer managing its costs?

A: The company is implementing a cost realignment program to achieve at least $4 billion in annual net cost savings by the end of 2024 and a manufacturing optimization program to save $1.5 billion by 2027[2].

Q: What are the potential risks to Pfizer's financial performance?

A: Risks include uncertainties around pipeline drug approvals and potential price reductions due to the Inflation Reduction Act[3].

Sources

  1. Pfizer Reports Full-Year 2023 Results and Reaffirms Full-Year 2024 Guidance - Pfizer.
  2. Pfizer Posts First Quarterly Revenue Growth Since Peak COVID Vaccine Sales - Investopedia.
  3. Krause Fund Research - Current Students - University of Iowa.
  4. Breakthroughs changing more than 1.3 billion lives - Pfizer - Pfizer.
  5. Pfizer, Inc.: Financial Data Forecasts Estimates and Expectations - Marketscreener.

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