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Last Updated: December 22, 2024

PYRIMETHAMINE Drug Patent Profile


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DrugPatentWatch® Litigation and Generic Entry Outlook for Pyrimethamine

A generic version of PYRIMETHAMINE was approved as pyrimethamine by SANALUZ on February 28th, 2020.

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Summary for PYRIMETHAMINE
Drug patent expirations by year for PYRIMETHAMINE
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Recent Clinical Trials for PYRIMETHAMINE

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SponsorPhase
Kamuzu University of Health SciencesPhase 4
Malaria ConsortiumPhase 3
Washington University School of MedicineEarly Phase 1

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Pharmacology for PYRIMETHAMINE
Medical Subject Heading (MeSH) Categories for PYRIMETHAMINE
Anatomical Therapeutic Chemical (ATC) Classes for PYRIMETHAMINE

US Patents and Regulatory Information for PYRIMETHAMINE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Alvogen PYRIMETHAMINE pyrimethamine TABLET;ORAL 211271-001 Jul 27, 2021 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Teva Pharms PYRIMETHAMINE pyrimethamine TABLET;ORAL 215506-001 Aug 13, 2021 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Aurobindo Pharma Ltd PYRIMETHAMINE pyrimethamine TABLET;ORAL 216983-001 Oct 25, 2022 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Sanaluz PYRIMETHAMINE pyrimethamine TABLET;ORAL 207127-001 Feb 28, 2020 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

PYRIMETHAMINE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Pyrimethamine

Market Overview

Pyrimethamine, a crucial antiparasitic medication, is listed on the World Health Organization’s (WHO) list of essential medicines. It is primarily used to treat and prevent protozoan infections such as malaria and toxoplasmosis, particularly in immunocompromised patients, including those with HIV/AIDS[1][4].

Market Size and Growth

The global pyrimethamine market is projected to experience significant growth over the coming years. As of 2021, the market was valued at approximately USD 1.51 billion and is expected to reach USD 2.32 billion by 2029, growing at a Compound Annual Growth Rate (CAGR) of 5.50% during the forecast period of 2022-2029[1].

Another report indicates that the market was valued at USD 1,106.8 million in 2021 and is anticipated to reach USD 1,792.0 million by 2030, with a CAGR of 5.5% from 2021 to 2030[4].

Segmentation Analysis

The pyrimethamine market is segmented based on several key factors:

Indications

  • The primary indications for pyrimethamine include malaria and toxoplasmosis, with other parasitic infections also being treated with this drug[1][4].

Route of Administration

  • The oral route is the most common and convenient method of administration, with most products available in capsule and tablet forms[1].

End Users

  • Hospitals, homecare, specialty clinics, and other healthcare settings are the main end users. Hospitals dominated the market with a significant share, driven by the need for treating serious parasitic infections[1][4].

Distribution Channels

  • The distribution channels include hospital pharmacies, online pharmacies, and retail pharmacies. Hospital pharmacies play a crucial role due to the immediate need for the medication in clinical settings[1].

Drivers of Market Growth

Several factors are driving the growth of the pyrimethamine market:

Increase in HIV Cases

  • The rising number of HIV-positive individuals worldwide increases the demand for pyrimethamine, as it is used to prevent and treat toxoplasmosis and other opportunistic infections in these patients[1][4].

Rising Demand for Oral Drugs

  • The convenience and effectiveness of oral drugs have boosted the market growth, as most pyrimethamine products are available in oral forms[1].

Increasing Drug Development and Research Activities

  • Ongoing research and development activities aimed at improving the efficacy and safety of pyrimethamine formulations are expected to drive market growth[1].

Challenges and Restraints

Despite the growth drivers, the market faces several challenges:

High Cost

  • The significant expenditure associated with pyrimethamine and its formulations can hamper market growth, especially in regions with limited healthcare budgets[1].

Side Effects

  • The medication is associated with various side effects, including allergic reactions, blood disorders, and heart rhythm disorders, which can act as a restraining factor for market growth[1].

Impact of COVID-19

The COVID-19 pandemic has had a mixed impact on the pyrimethamine market:

Short-Term Disruptions

  • The pandemic led to delays in clinical trials and disruptions in healthcare infrastructure, which temporarily affected the market[1].

Long-Term Opportunities

  • The increased focus on biotechnology and pharmaceuticals during the pandemic is expected to drive future growth in the market, particularly for essential medications like pyrimethamine[1].

Regional Analysis

The global pyrimethamine market is geographically diverse:

North America

  • North America dominates the market due to the presence of key manufacturers, high research and development investments, and significant healthcare expenditure[1][4].

Asia-Pacific

  • The Asia-Pacific region is expected to grow at the fastest CAGR during the forecast period, driven by government awareness programs and an increased prevalence of malaria and AIDS[1][4].

Competitive Landscape

The market is characterized by the presence of several key players:

Major Market Players

  • Companies such as Vyera Pharmaceuticals, LLC, GlaxoSmithKline plc, Impax Laboratories, Inc., Pfizer, Inc., and others play significant roles in the market[4].

Innovative Strategies

  • Companies like Imprimis Pharmaceuticals have introduced cost-effective formulations by leveraging compounding regulations to undercut high-priced generic drugs, thereby increasing market competition and accessibility[2].

Financial Trajectory

The financial trajectory of the pyrimethamine market is marked by steady growth:

Revenue Growth

  • The market is expected to grow from USD 1.51 billion in 2021 to USD 2.32 billion by 2029, and from USD 1,106.8 million in 2021 to USD 1,792.0 million by 2030, indicating a robust financial outlook[1][4].

Profitability

  • Despite the challenges, companies can achieve profitability by offering cost-effective formulations and leveraging compounding regulations, as seen with Imprimis Pharmaceuticals[2].

Key Takeaways

  • The global pyrimethamine market is driven by the increasing number of HIV cases and the demand for oral antiparasitic drugs.
  • The market faces challenges such as high costs and side effects but is expected to grow steadily.
  • North America and the Asia-Pacific region are key markets, with the latter expected to grow at the fastest CAGR.
  • Innovative strategies by companies like Imprimis Pharmaceuticals are enhancing market competition and accessibility.

FAQs

1. What is the current market size of the pyrimethamine market?

  • The market was valued at approximately USD 1.51 billion in 2021 and USD 1,106.8 million in another report[1][4].

2. What is the expected CAGR of the pyrimethamine market?

  • The market is expected to grow at a CAGR of 5.50% from 2022 to 2029 and 5.5% from 2021 to 2030[1][4].

3. Which region dominates the pyrimethamine market?

  • North America currently dominates the market, but the Asia-Pacific region is expected to grow at the fastest rate[1][4].

4. What are the primary indications for pyrimethamine?

  • The primary indications include malaria and toxoplasmosis[1][4].

5. How has the COVID-19 pandemic affected the pyrimethamine market?

  • The pandemic caused short-term disruptions but is expected to drive long-term growth in the biotechnology and pharmaceutical sectors[1].

Citations

  1. Data Bridge Market Research: Global Pyrimethamine Market – Industry Trends and Forecast to 2029.
  2. Los Angeles Times: Drug pricing: That pill that went from $13.50 to $750 can now be had for $1.
  3. Market Research Intellect: Pyrimethamine Tablets Market Size, Scope And Forecast Report.
  4. Spherical Insights: Pyrimethamine Market Size, Trend during Forecast 2030.
  5. Unitaid: Call for proposals: Intermittent Preventive Treatment in infants.

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