RETIN-A Drug Patent Profile

Which patents cover Retin-a, and what generic alternatives are available?

Retin-a is a drug marketed by Bausch, Valeant Bermuda, Valeant Pharms North, and Valeant Intl. and is included in seven NDAs.

The generic ingredient in RETIN-A is tretinoin. There are twenty-six drug master file entries for this compound. Twenty-six suppliers are listed for this compound. Additional details are available on the tretinoin profile page.

DrugPatentWatch^® Litigation and Generic Entry Outlook for Retin-a

A generic version of RETIN-A was approved as tretinoin by PADAGIS US on December 24^th, 1998.

Summary for RETIN-A

US Patents:	0
Applicants:	4
NDAs:	7
Finished Product Suppliers / Packagers:	4
Raw Ingredient (Bulk) Api Vendors:	140
Drug Prices:	Drug price information for RETIN-A
Drug Sales Revenues:	Drug sales revenues for RETIN-A
What excipients (inactive ingredients) are in RETIN-A?	RETIN-A excipients list
DailyMed Link:	RETIN-A at DailyMed

See drug prices for RETIN-A

See drug sales revenues for RETIN-A

Pharmacology for RETIN-A

Drug Class

Retinoid

US Patents and Regulatory Information for RETIN-A

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Bausch	RETIN-A	tretinoin	CREAM;TOPICAL	019049-001	Sep 16, 1988	AB	RX	Yes	Yes
Valeant Intl	RETIN-A	tretinoin	SWAB;TOPICAL	016921-002	Approved Prior to Jan 1, 1982		DISCN	No	No
Valeant Intl	RETIN-A	tretinoin	GEL;TOPICAL	017955-001	Approved Prior to Jan 1, 1982	AB	RX	Yes	Yes
Bausch	RETIN-A MICRO	tretinoin	GEL;TOPICAL	020475-002	May 10, 2002		RX	Yes	Yes
Valeant Bermuda	RETIN-A	tretinoin	CREAM;TOPICAL	017522-001	Approved Prior to Jan 1, 1982	AB1	RX	Yes	Yes

Expired US Patents for RETIN-A

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Valeant Intl	RETIN-A	tretinoin	GEL;TOPICAL	017579-002	Approved Prior to Jan 1, 1982
Valeant Pharms North	RETIN-A	tretinoin	CREAM;TOPICAL	017340-001	Approved Prior to Jan 1, 1982
Valeant Intl	RETIN-A	tretinoin	GEL;TOPICAL	017579-002	Approved Prior to Jan 1, 1982
Bausch	RETIN-A	tretinoin	CREAM;TOPICAL	019049-001	Sep 16, 1988
Valeant Intl	RETIN-A	tretinoin	GEL;TOPICAL	017955-001	Approved Prior to Jan 1, 1982

International Patents for RETIN-A

See the table below for patents covering RETIN-A around the world.

Country	Patent Number	Title	Estimated Expiration
Denmark	136178
France	2070083
Luxembourg	71080
Finland	57055
Philippines	11954	STABILIZED TRETINOIN CREAM EMULSION

Supplementary Protection Certificates for RETIN-A

Patent Number	Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description
1304992	SPC/GB13/061	United Kingdom		PRODUCT NAME: CLINDAMYCIN PHOSPHATE IN COMBINATION WITH TRETINOIN.; REGISTERED: IE PA1332/043/001 20130322; UK PL15142/0249 20130624
1304992	2013C/060	Belgium		PRODUCT NAME: CLINDAMYCINE (ALS CLINDAMYCINE FOSFAAT) EN TRETINOINE; AUTHORISATION NUMBER AND DATE: BE437507 20130506
1304992	PA2013025	Lithuania		PRODUCT NAME: CLINFAMYCINUM + TRETINOINUM; REGISTRATION NO/DATE: LT/1/13/3279/001, 2013 04 26 LT/1/13/3279/002, 2013 04 26 PA1332/043/001 20130323
1304992	122013000081	Germany		PRODUCT NAME: CLINDAMYCIN (ALS CLINDAMYCIN-PHOSPHAT) UND TRETINOIN; NAT. REGISTRATION NO/DATE: 85210.00.00 20130611; FIRST REGISTRATION: IRLAND PA1332/043/001 20130322
1304992	1390049-3	Sweden		PRODUCT NAME: KLINDAMYCIN (SOM KLINDAMYCINFOSFAT) OCH TRETINOIN; NAT. REG. NO/DATE: MTNR 46193 20130503; FIRST REG.: IR PA1332/043/001 20130322

RETIN-A Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Retin-A (Retinol)

Introduction to Retin-A (Retinol)

Retin-A, commonly known as retinol, is a derivative of vitamin A that has become a cornerstone in the skincare industry. It is widely recognized for its efficacy in addressing various skin concerns such as aging, acne, and hyperpigmentation. Here, we will delve into the market dynamics and financial trajectory of retinol, providing insights into its current state, future projections, and the factors influencing its growth.

Market Size and Growth Projections

The global retinol market has been experiencing steady growth. As of 2023, the market size was valued at approximately USD 1.43 billion and is expected to reach USD 1.87 billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 3.9%[1][4].

Regional Insights

Europe

Europe dominated the largest share of the retinol market in 2022. The region's stringent regulations and standards for skincare and cosmetic products have driven the emphasis on product safety, quality, and ingredient efficacy. Consumers in Europe are highly aware of the importance of healthy and youthful-looking skin, which has increased the demand for scientifically proven ingredients like retinol[1].

North America

North America is expected to grow at the highest CAGR during the forecast period. The aging population in this region has been a significant driver for the demand in anti-aging skincare products, which includes retinol-based products[1].

Market Drivers

Several factors are driving the growth of the retinol market:

Increasing Awareness of Skincare Benefits

There is a rising awareness among consumers about the health benefits of retinol, particularly its anti-aging properties. This increased awareness has led to a higher demand for skincare products containing retinol[4].

Demand for Anti-Aging Skincare

The global population is aging, and with it, there is a growing demand for anti-aging skincare products. Retinol, with its well-documented benefits in reducing fine lines, wrinkles, and hyperpigmentation, is a key ingredient in many of these products[1][4].

Advancements in Formulation Technology

Advancements in formulation technology have made retinol more stable and effective in various skincare products. This has expanded its application across different product types, including creams, serums, and oils[4].

Clean Beauty and Personalized Skincare Trends

Trends such as clean beauty and personalized skincare are opening new avenues for retinol applications. Consumers are increasingly looking for premium and chemical-free skincare products, which retinol can fulfill[4].

Market Restraints

Despite the growth, there are several challenges facing the retinol market:

Potential Skin Sensitivity Issues

One of the significant restraints is the potential for skin sensitivity issues associated with retinol use. This can deter some consumers from using retinol-based products[4].

Stringent Regulatory Frameworks

The skincare industry is subject to stringent regulatory frameworks, which can be a challenge for manufacturers. Ensuring compliance with these regulations can be costly and time-consuming[1][4].

High Cost of Retinol Products

The high cost of retinol products can be a barrier for price-sensitive consumers, limiting the market's potential growth[4].

Market Opportunities

There are several opportunities that could further drive the growth of the retinol market:

Development of Retinol with Other Active Ingredients

The development of retinol combined with other active ingredients such as stem cells and plant-based topicals presents a significant opportunity. These combinations can enhance the efficacy and appeal of retinol products[4].

Availability on Retail and E-Commerce Portals

The increasing availability of retinol products on retail and e-commerce platforms has made it easier for consumers to access these products, thereby driving demand[4].

Financial Forecasting for Retinol Market

To create a financial forecast for a business involved in the retinol market, several steps can be taken:

Setting Sales Projections

Start by setting a goal for sales. For example, if a company made $1 million in sales in the current year, it might aim to increase sales to $1.5 million in the next year. This increase should be mapped out over the forecast period, typically on a monthly basis[2][5].

Creating Pro Forma Income Statements

Calculate the cost of goods sold and other operating expenses for each month. Deduct these expenses from the projected sales to get the net income. This process helps in creating pro forma income statements that show expected earnings and expenses[2].

Accounting for Expenses

Include all expenses, such as increased marketing or production costs, in the forecast. For instance, if the plan involves quadrupling online advertising, this expense should be reflected in the financial forecast[2].

Adjusting Based on Performance

Regularly review and adjust the financial forecast based on actual performance. If revenue exceeds projections, the budget can be adjusted to reinvest in the business[2].

Example Financial Forecast

Consider a company that produces retinol-based skincare products. Here’s a simplified example:

• Projected Sales: Increase from $1 million to $1.5 million over the next year.
• Monthly Sales Increase: $41,667 per month ($500,000 / 12 months).
• Cost of Goods Sold: 30% of sales.
• Operating Expenses: $200,000 per year, divided equally across 12 months.

By mapping out these figures, the company can create a detailed financial forecast that helps in planning and decision-making.

Key Takeaways

• The retinol market is expected to grow at a CAGR of 3.9% from 2023 to 2030.
• Europe and North America are key regions driving the market growth.
• Increasing awareness of skincare benefits, demand for anti-aging products, and advancements in formulation technology are major drivers.
• Potential skin sensitivity issues, stringent regulations, and high product costs are significant restraints.
• Development of retinol with other active ingredients and increased availability on retail and e-commerce platforms present opportunities for growth.
• Accurate financial forecasting is crucial for businesses to plan and invest effectively in the retinol market.

FAQs

Q: What is the current market size of the retinol market?

The global retinol market was valued at approximately USD 1.43 billion in 2023[1].

Q: What is the expected CAGR of the retinol market from 2023 to 2030?

The retinol market is expected to grow at a CAGR of 3.9% from 2023 to 2030[1].

Q: Which region dominates the retinol market?

Europe dominated the largest share of the retinol market in 2022 due to stringent regulations and consumer awareness of skincare benefits[1].

Q: What are the main drivers of the retinol market?

The main drivers include increasing awareness of skincare benefits, demand for anti-aging products, and advancements in formulation technology[1][4].

Q: What are some of the challenges facing the retinol market?

Challenges include potential skin sensitivity issues, stringent regulatory frameworks, and the high cost of retinol products[4].

Sources

1. Maximize Market Research: Retinol Market: Industry Analysis and Forecast (2024-2030)
2. Bench Accounting: How to Create a Financial Forecast - Bench Accounting
3. Market Research Intellect: Tretinoin Drugs Industry Market Size, Scope and Forecast Report
4. Research and Markets: Retinol Market Size, Competitors, Trends & Forecast to 2030
5. U.S. Chamber of Commerce: How to Write a Financial Forecast for Your Business | CO