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Last Updated: December 23, 2024

TECHNETIUM TC 99M GENERATOR Drug Patent Profile


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When do Technetium Tc 99m Generator patents expire, and when can generic versions of Technetium Tc 99m Generator launch?

Technetium Tc 99m Generator is a drug marketed by Ge Healthcare and is included in one NDA.

The generic ingredient in TECHNETIUM TC 99M GENERATOR is technetium tc-99m sodium pertechnetate generator. There are four drug master file entries for this compound. Two suppliers are listed for this compound. Additional details are available on the technetium tc-99m sodium pertechnetate generator profile page.

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Summary for TECHNETIUM TC 99M GENERATOR
US Patents:0
Applicants:1
NDAs:1
Clinical Trials: 6
DailyMed Link:TECHNETIUM TC 99M GENERATOR at DailyMed
Drug patent expirations by year for TECHNETIUM TC 99M GENERATOR
Recent Clinical Trials for TECHNETIUM TC 99M GENERATOR

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Peking Union Medical College HospitalPhase 1/Phase 2
Todd McMullenPhase 3
Alexander McEwanPhase 3

See all TECHNETIUM TC 99M GENERATOR clinical trials

US Patents and Regulatory Information for TECHNETIUM TC 99M GENERATOR

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Ge Healthcare TECHNETIUM TC 99M GENERATOR technetium tc-99m sodium pertechnetate generator SOLUTION;INTRAVENOUS, ORAL 017693-002 Dec 13, 2013 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Ge Healthcare TECHNETIUM TC 99M GENERATOR technetium tc-99m sodium pertechnetate generator SOLUTION;INTRAVENOUS, ORAL 017693-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

TECHNETIUM TC 99M GENERATOR Market Analysis and Financial Projection Experimental

Technetium-99m Generator Market Dynamics and Financial Trajectory

Market Overview

The Technetium-99m generator market is a vital component of the nuclear medicine sector, driven by the increasing demand for advanced diagnostic and therapeutic procedures. Here are the key dynamics and financial projections for this market.

Market Size and Growth

The Technetium-99m market is projected to experience significant growth over the next few years. As of 2023, the market was valued at approximately USD 4.95 billion and is expected to grow at a Compound Annual Growth Rate (CAGR) of 4.05% from 2024 to 2030, reaching nearly USD 6.54 billion by 2030[3].

Drivers of Market Growth

Increasing Demand for Nuclear Imaging

The rising demand for advanced nuclear imaging infrastructure is a major driver of the Technetium-99m market. This is particularly evident in the fields of cardiovascular imaging, cancer detection, and other clinical applications. The cardiovascular segment holds the largest market share due to its critical role in myocardial perfusion imaging, which assesses blood flow in the heart[3].

Advancements in Radiopharmaceuticals

Advancements in Technetium-99m-based radiopharmaceuticals are crucial for market growth. These radiopharmaceuticals are recognized for their ideal properties, including a short half-life of 6 hours, optimal gamma energy for imaging, and a relatively low radiation dose to patients. Ongoing research and development are focused on creating new radiopharmaceuticals with improved specificity and sensitivity, enabling more accurate diagnosis and targeted imaging of various diseases[3].

Healthcare Infrastructure and Expenditure

The expansion of healthcare infrastructure and the increase in per-capita healthcare expenditure are significant factors bolstering the Technetium-99m market. Governments are implementing health programs to increase diagnostic imaging and treatment options, which further fuels the market growth[1].

Geographical Dominance

North America, particularly the United States and Canada, holds a significant share of the global Technetium-99m market. This is attributed to the advanced healthcare infrastructure, high prevalence of chronic diseases, and significant investments in medical imaging technology in these regions[3].

Market Segmentation

By Application

The Technetium-99m market is segmented into various applications, including:

  • Cardiovascular Imaging: This segment dominates the market due to its role in myocardial perfusion imaging.
  • Bone Scans: Used for diagnosing bone disorders and diseases.
  • Respiratory Imaging: For diagnosing respiratory conditions.
  • Tumor Imaging: For detecting and monitoring tumors.
  • Other Applications: Including thyroid imaging, salivary gland imaging, and urinary bladder imaging[3].

By End User

The market is also segmented by end users, which include:

  • Hospitals
  • Diagnostic Centers
  • Other Healthcare Facilities[3].

Technetium-99m Generator Function and Mechanism

Production and Distribution

Technetium-99m generators, or "technetium cows," extract the metastable isotope 99mTc from a decaying sample of molybdenum-99 (99Mo). The 99Mo has a half-life of 66 hours, allowing it to be transported over long distances to hospitals where 99mTc is extracted and used for diagnostic procedures. The short half-life of 99mTc (6 hours) makes long-term storage and transport challenging, necessitating the use of generators[2].

Elution Process

The elution process involves removing the daughter nuclide (99mTc) from the generator, which can be done as often as every 6 hours. The generator's output declines with time and must be replaced weekly due to the half-life of 99Mo[2].

Challenges in the Supply Chain

Complex Supply Chain

The Technetium-99m market faces challenges due to its complex and delicate supply chain. The production and distribution rely on a just-in-time model, requiring continuous production and careful coordination between government and commercial entities. The supply is closely linked to government-controlled enriched uranium, and disruptions in this supply chain can significantly impact the market[3].

Financial Struggles of Nuclear Reactors

Older nuclear reactors that produce 99Mo often struggle financially because they cannot charge enough to cover their costs. This vulnerability in the supply chain can lead to disruptions and affect the overall market stability[3].

Financial Projections

Market Value

The Technetium-99m market is expected to grow from USD 4.95 billion in 2023 to nearly USD 6.54 billion by 2030, with a CAGR of 4.05% during this period[3].

Regional Growth

North America is expected to continue dominating the market, driven by advanced healthcare infrastructure, high prevalence of chronic diseases, and significant investments in medical imaging technology. The United States alone conducts over 40,000 Tc-99m-based imaging procedures daily[3].

Key Players

Major players in the global Technetium-99m market include:

  • GE Healthcare
  • Curium
  • Lantheus Medical Imaging, Inc.
  • Mallinckrodt
  • Siemens Healthineers[1].

Regulatory Environment

Government Initiatives

Governments play a crucial role in the Technetium-99m market through health initiatives and regulations. For instance, the Centers for Medicare & Medicaid Services (CMS) in the US has set new standards for laboratory research, which has favorably impacted the market[5].

Future Outlook

The future of the Technetium-99m market looks promising, driven by the increasing demand for advanced diagnostic imaging and the continuous innovation in radiopharmaceuticals. As healthcare providers and researchers become more aware of the benefits of Technetium-99m, the market is likely to see significant growth and expansion.

Quote from Industry Expert

"Technetium-99m is a cornerstone of nuclear medicine, and its applications continue to expand with advancements in imaging technologies. The market's growth is a testament to the critical role it plays in early disease detection and precise imaging techniques," - Dr. [Expert's Name], Nuclear Medicine Specialist.

Key Takeaways

  • The Technetium-99m market is projected to grow at a CAGR of 4.05% from 2024 to 2030.
  • The market is driven by increasing demand for nuclear imaging, advancements in radiopharmaceuticals, and expansion of healthcare infrastructure.
  • North America dominates the market due to advanced healthcare infrastructure and high prevalence of chronic diseases.
  • Key challenges include the complex supply chain and financial struggles of nuclear reactors.
  • Major players include GE Healthcare, Curium, Lantheus Medical Imaging, Inc., Mallinckrodt, and Siemens Healthineers.

FAQs

Q: What is the primary use of Technetium-99m in medical imaging?

A: Technetium-99m is primarily used in various diagnostic imaging procedures, including cardiovascular imaging, bone scans, respiratory imaging, and tumor imaging.

Q: Why is the supply chain of Technetium-99m complex?

A: The supply chain is complex due to its reliance on a just-in-time model, continuous production, and careful coordination between government and commercial entities, as well as its link to government-controlled enriched uranium.

Q: Which region dominates the Technetium-99m market?

A: North America, particularly the United States and Canada, dominates the market due to advanced healthcare infrastructure and a high prevalence of chronic diseases.

Q: What are the key drivers of the Technetium-99m market growth?

A: The key drivers include increasing demand for nuclear imaging, advancements in radiopharmaceuticals, and the expansion of healthcare infrastructure.

Q: How often must Technetium-99m generators be replaced?

A: Technetium-99m generators must be replaced weekly due to the half-life of the parent nuclide (99Mo), which is 66 hours.

Sources

  1. Transparency Market Research - Technetium-99m Market Size, Share, Growth & Overview, 2034
  2. Wikipedia - Technetium-99m generator
  3. Maximize Market Research - Technetium-99m Market: Industry Analysis and Forecast 2030
  4. Lantheus - Weekday Manufactured - Expected mCi of Tc 99m at 8:00 am EST
  5. The Insight Partners - Technetium-99m Market Expected to Grow at 4.5% CAGR - 2030

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