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Last Updated: December 22, 2024

TOPOSAR Drug Patent Profile


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When do Toposar patents expire, and what generic alternatives are available?

Toposar is a drug marketed by Teva Parenteral and is included in one NDA.

The generic ingredient in TOPOSAR is etoposide. There are eleven drug master file entries for this compound. Five suppliers are listed for this compound. Additional details are available on the etoposide profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Toposar

A generic version of TOPOSAR was approved as etoposide by HIKMA on July 17th, 1995.

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Drug patent expirations by year for TOPOSAR
Drug Prices for TOPOSAR

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Recent Clinical Trials for TOPOSAR

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University of California, San FranciscoPhase 2
RenJi HospitalPhase 2
Incyte CorporationPhase 2

See all TOPOSAR clinical trials

US Patents and Regulatory Information for TOPOSAR

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Teva Parenteral TOPOSAR etoposide INJECTABLE;INJECTION 074166-001 Feb 27, 1995 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

TOPOSAR Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Etoposide (TOPOSAR)

Introduction

Etoposide, marketed under the brand name TOPOSAR, is a chemotherapeutic agent widely used in the treatment of various types of cancer, including small cell lung cancer, testicular cancer, and other malignancies. This article delves into the market dynamics and financial trajectory of etoposide, highlighting key drivers, restraints, and future prospects.

Market Size and Growth Rate

The global etoposide market was valued at US$ 715.62 million in 2023 and is expected to grow at a Compound Annual Growth Rate (CAGR) of 5.8% from 2024 to 2030, reaching approximately US$ 1061.89 million by the end of the forecast period[1].

Primary Drivers

Growing Prevalence of Prostate Cancer

One of the primary drivers of the etoposide market is the increasing prevalence of prostate cancer. Prostate cancer is the second most common type of cancer among men, with 1.4 million cases globally in 2021, accounting for 7.2% of all malignant tumors[1].

Aging Population

The global aging population is another significant factor driving the market. The number of people aged 65 and older is projected to increase from 725 million in 2021 to 1.45 billion by 2050, which will lead to a higher incidence of age-related cancers[1].

Key Applications

Small Cell Lung Cancer

Etoposide is extensively used in the treatment of small cell lung cancer, which is expected to grow at a CAGR of 3.8% during the forecast period. Its efficacy in this application is a major contributor to the market growth[1].

Testicular Cancer

The drug is also crucial in treating testicular cancer. The global testicular cancer drugs market, which includes etoposide, is driven by the availability of combination therapies and early diagnostic methods, further boosting the growth of this segment[4].

Regional Insights

North America

North America, particularly the United States and Canada, is expected to hold a significant market share due to the rising frequency of prostate cancer, increasing awareness, and enhanced research and development activities in the region. According to the American Cancer Society, an estimated 265,000 new prostate cancer cases were expected in the U.S. in 2023, with a high incidence among men aged 64 and older[1].

Restraints

High Cost of Cancer Medications

One of the major restraints for the etoposide market is the high cost of cancer medications, especially those for lung cancer. The treatment of lung cancer involves significant expenses, including imaging, operations, pharmaceutical aid, and indirect costs such as mobility, caregiver salaries, and lost wages. These high costs place a substantial burden on governments and patients worldwide[1].

Ongoing Research and Development

Clinical Studies and New Therapies

Ongoing clinical research is expected to enhance the clinical efficacy of etoposide. Studies are focusing on the optimal dose and timing of etoposide, as well as its potential use in combination therapies for cervical cancer, breast cancer, and various pediatric cancers. The use of etoposide in conjunction with topoisomerase I blockers and the development of medications to reverse treatment resistance are also being explored[1].

Market Segmentation

By Form

Etoposide is available in two primary forms: injection and oral. Each form has its own market share and growth prospects, with the injection form being more commonly used in clinical settings[1].

By Application

The market is segmented by application into small cell lung cancer, testicular cancer, and other types of cancer. Small cell lung cancer is a significant segment due to the high efficacy of etoposide in treating this condition[1].

Competitive Landscape

Key Players

Major pharmaceutical companies such as Pfizer and Teva Pharmaceutical are key players in the etoposide market. Pfizer offers TOPOSAR, while Teva Pharmaceutical provides PLATINOL, which is used in combination with other medications to treat various types of cancer[4].

Global Oncology Market Context

The global oncology market is expected to grow significantly, from around USD 105 billion to USD 150 billion by 2020. This growth is driven by the increasing incidence of cancer and the need for effective treatments. Pharmaceutical companies are investing in access to affordable, quality cancer medicines and contributing to the development of resilient health systems, especially in low- and middle-income countries[3].

Access to Cancer Care

Access to cancer care, including treatment, prevention, diagnosis, and palliative care, is a critical issue globally. The World Health Organization (WHO) estimates that cancer deaths will increase by 45% to 11.5 million by 2030, with 65% of these deaths occurring in developing countries. Pharmaceutical companies have a significant role in improving the accessibility and affordability of cancer medicines in these regions[3].

Financial Implications

Cost and Budget Impact

The high cost of cancer medications, including etoposide, has significant financial implications for both governments and patients. The treatment costs, including direct and indirect expenditures, place a substantial burden on healthcare systems worldwide[1].

Funding and Research

The growth of the etoposide market is also influenced by funding and research initiatives. Governments and pharmaceutical companies are investing in early-phase drug approvals and clinical research, which is expected to accelerate the development of new cancer therapies[1].

Key Takeaways

  • The etoposide market is driven by the growing prevalence of prostate cancer and the aging population.
  • North America is expected to hold a significant market share due to high incidence rates and advanced healthcare infrastructure.
  • High costs of cancer medications are a major restraint for market growth.
  • Ongoing clinical research is expected to enhance the efficacy and application of etoposide.
  • The global oncology market is growing, with a focus on improving access to affordable cancer treatments.

FAQs

What is the primary driver of the etoposide market?

The primary driver of the etoposide market is the growing prevalence of prostate cancer.

Which region is expected to hold a significant market share for etoposide?

North America, particularly the United States and Canada, is expected to hold a considerable market share.

What are the major restraints for the etoposide market?

The high cost of cancer medications, especially for lung cancer, is a major restraint for the etoposide market.

What is the projected market size and growth rate of the etoposide market?

The etoposide market was valued at US$ 715.62 million in 2023 and is expected to grow at a CAGR of 5.8% to reach nearly US$ 1061.89 million by 2030.

What are the key applications of etoposide?

Etoposide is primarily used in the treatment of small cell lung cancer and testicular cancer.

Sources

  1. Maximize Market Research: Etoposide Market - Region and Forecast (2024-2030)
  2. Riverside County Clerk of the Board: Financial Data and Capital Assets
  3. Access to Medicine Foundation: Improving access to cancer care
  4. BioSpace: Testicular Cancer Drugs Market 2019-2023 | Technavio

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