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Last Updated: March 18, 2025

TRIAVIL 4-10 Drug Patent Profile


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Which patents cover Triavil 4-10, and when can generic versions of Triavil 4-10 launch?

Triavil 4-10 is a drug marketed by New River and is included in one NDA.

The generic ingredient in TRIAVIL 4-10 is amitriptyline hydrochloride; perphenazine. There are thirteen drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the amitriptyline hydrochloride; perphenazine profile page.

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Summary for TRIAVIL 4-10
US Patents:0
Applicants:1
NDAs:1
Raw Ingredient (Bulk) Api Vendors: 5
Patent Applications: 26
DailyMed Link:TRIAVIL 4-10 at DailyMed
Drug patent expirations by year for TRIAVIL 4-10

US Patents and Regulatory Information for TRIAVIL 4-10

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
New River TRIAVIL 4-10 amitriptyline hydrochloride; perphenazine TABLET;ORAL 014715-003 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 1 of 1 entries

Expired US Patents for TRIAVIL 4-10

ApplicantTradenameGeneric NameDosageNDAApproval DatePatent No.Patent Expiration
New River TRIAVIL 4-10 amitriptyline hydrochloride; perphenazine TABLET;ORAL 014715-003 Approved Prior to Jan 1, 1982 ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>Patent No.>Patent Expiration
Showing 1 to 1 of 1 entries

Market Dynamics and Financial Trajectory for TRIAVIL 4-10

Introduction

TRIAVIL 4-10, a combination of amitriptyline and perphenazine, is a psychotherapeutic medication used to treat conditions such as agitation, anxiety, and depression. To understand the market dynamics and financial trajectory of this drug, it is essential to analyze various factors including market trends, pricing, availability, and the broader healthcare landscape.

Market Trends in Psychotherapeutic Medications

The market for psychotherapeutic medications is influenced by several key trends. One significant trend is the increasing demand for innovative therapeutics, which is driving spending growth in the pharmaceutical sector. According to the IQVIA Institute, the availability and use of innovative therapeutics in developed markets are expected to be the largest drivers of medicine spending growth through 2028[1].

Pricing and Affordability

High drug prices are a significant concern in the healthcare sector. The issue of affordability affects many patients, with nearly 30% of Americans reporting that they have not taken their medication as prescribed due to high costs. This trend is particularly problematic for medications like TRIAVIL 4-10, which may be prescribed for chronic conditions requiring long-term treatment[4].

Impact on Patient Access

The high prices of medications can jeopardize patient access to necessary care. For TRIAVIL 4-10, this means that patients may struggle to afford the medication, leading to potential gaps in treatment. This not only affects patient outcomes but also adds to the broader healthcare costs due to complications arising from untreated or undertreated conditions.

Drug Shortages and Supply Chain Issues

Drug shortages are another critical factor affecting the market dynamics of TRIAVIL 4-10. In 2023, there was an average of 301 drugs in shortage per quarter, with generic drugs making up as much as 83% of these shortages. This is often due to decisions by drug companies that lack incentives to produce low-margin medications[4].

Impact on TRIAVIL 4-10

Given that TRIAVIL 4-10 is a generic or combination medication, it may be more susceptible to shortages. These shortages can exacerbate the challenges faced by hospitals and health systems, further stretching their limited resources and impacting patient care.

Financial Trajectory

Spending Growth

The financial trajectory for TRIAVIL 4-10 is tied to the broader trends in pharmaceutical spending. While innovative therapeutics are driving spending growth, the impact of generic and biosimilar drugs cannot be overlooked. The IQVIA Institute reports that the growth in spending is also influenced by the mix of volume-driven growth and changes in the cost of therapy, with many geographies shifting towards more expensive therapies[1].

Revenue Projections

For TRIAVIL 4-10, revenue projections would need to account for the balance between the demand for psychotherapeutic medications and the challenges posed by high prices and potential shortages. Given the generic nature of the drug, revenue may be more stable but could be impacted by competition from other generic or branded alternatives.

Regulatory and Market Environment

The regulatory environment plays a crucial role in shaping the market dynamics of any drug. For TRIAVIL 4-10, being a combination of amitriptyline and perphenazine, it must comply with FDA regulations and guidelines. Any changes in regulatory policies or the approval of new therapies could influence the market position of TRIAVIL 4-10[2].

Patient and Prescriber Preferences

Patient and prescriber preferences also influence the market trajectory. The efficacy, safety profile, and side effects of TRIAVIL 4-10 compared to other available treatments can affect its adoption. For instance, amitriptyline, a component of TRIAVIL 4-10, has a well-documented mechanism of action and adverse effect profile, which can influence prescriber decisions[5].

Competitive Landscape

The competitive landscape for psychotherapeutic medications is diverse and dynamic. TRIAVIL 4-10 competes with other antidepressants and antipsychotics, both branded and generic. The introduction of new drugs or changes in the market share of existing drugs can impact the financial trajectory of TRIAVIL 4-10.

Global and Regional Market Analysis

The global use of medicines, including TRIAVIL 4-10, varies significantly by region. Developed markets tend to have higher spending on innovative therapeutics, while in developing markets, the focus may be more on affordable generic options. The IQVIA Institute's report highlights regional differences in spending and usage, which can inform market strategies for TRIAVIL 4-10[1].

Conclusion

The market dynamics and financial trajectory for TRIAVIL 4-10 are influenced by a complex interplay of factors including pricing, availability, regulatory environment, patient and prescriber preferences, and the broader healthcare landscape. As the pharmaceutical sector continues to evolve, understanding these trends is crucial for stakeholders to navigate the challenges and opportunities associated with this medication.

Key Takeaways

  • Pricing and Affordability: High drug prices and potential shortages can impact patient access and treatment outcomes.
  • Market Trends: The demand for innovative therapeutics drives spending growth, but generic and biosimilar drugs also play a significant role.
  • Regulatory Environment: Compliance with FDA regulations and guidelines is essential for market positioning.
  • Patient and Prescriber Preferences: Efficacy, safety profile, and side effects influence adoption rates.
  • Competitive Landscape: The market is competitive, with both branded and generic options available.

FAQs

What is TRIAVIL 4-10 used for?

TRIAVIL 4-10 is used in the treatment of agitation, anxiety, and depression. It is a combination of amitriptyline and perphenazine[2].

How does the pricing of TRIAVIL 4-10 affect patient access?

High drug prices can make it difficult for patients to afford TRIAVIL 4-10, leading to gaps in treatment and potentially worse patient outcomes[4].

What are the main challenges facing the market for TRIAVIL 4-10?

The main challenges include high drug prices, drug shortages, and the competitive landscape of psychotherapeutic medications[4].

How does the regulatory environment impact TRIAVIL 4-10?

The regulatory environment, including FDA guidelines and approvals, plays a crucial role in the market positioning and availability of TRIAVIL 4-10[2].

What are the projected revenue trends for TRIAVIL 4-10?

Revenue projections for TRIAVIL 4-10 are influenced by the balance between demand for psychotherapeutic medications and the challenges posed by high prices and potential shortages. The revenue may be stable but could be impacted by competition and market trends[1].

Sources

  1. IQVIA Institute. The Global Use of Medicines 2024: Outlook to 2028.
  2. Drugs.com. MSD 934 TRIAVIL Pill Brown Three-sided.
  3. Science.gov. Prazosin treatment suppresses.
  4. American Hospital Association. Drug Prices and Shortages Jeopardize Patient Access to Quality Hospital Care.
  5. DrugBank. Amitriptyline: Uses, Interactions, Mechanism of Action.

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