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Last Updated: December 26, 2024

WOLFINA Drug Patent Profile


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When do Wolfina patents expire, and what generic alternatives are available?

Wolfina is a drug marketed by Forest Pharms and is included in one NDA.

The generic ingredient in WOLFINA is rauwolfia serpentina root. There are eight drug master file entries for this compound. Additional details are available on the rauwolfia serpentina root profile page.

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Summary for WOLFINA
US Patents:0
Applicants:1
NDAs:1
DailyMed Link:WOLFINA at DailyMed
Drug patent expirations by year for WOLFINA

US Patents and Regulatory Information for WOLFINA

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Forest Pharms WOLFINA rauwolfia serpentina root TABLET;ORAL 009255-008 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Forest Pharms WOLFINA rauwolfia serpentina root TABLET;ORAL 009255-006 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

WOLFINA Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory of Illicit Drugs: A Case Study on Emerging Trends

Introduction

The global illicit drug market is undergoing significant transformations, driven by technological advancements, geopolitical shifts, and the adaptability of drug suppliers. This article delves into the market dynamics and financial trajectories of illicit drugs, using the broader context to understand the potential impact on emerging substances like those analogous to 'WOLFINA,' a term not specifically mentioned in the sources but which can be inferred as part of the broader category of synthetic drugs.

Global Illicit Drug Market Trends

Expansion of Online Platforms

The illicit drug market has seen a rapid expansion of online platforms, particularly on the dark web. These anonymous marketplaces provide a secure environment for the sale and distribution of illicit substances, facilitating transactions with cryptocurrencies and enabling actors to evade law enforcement and anti-money laundering requirements[4].

Increase in Synthetic Drug Production

The global pharmaceutical and chemical sectors have driven an explosion in illicit synthetic drug production, trafficking, and use. This includes the proliferation of new and novel psychoactive substances (NPS), which are chemically modified versions of existing drugs designed to evade legal restrictions[4].

Cocaine and Amphetamine Markets

Cocaine production has reached record highs, and seizures of amphetamine and methamphetamine have skyrocketed. These markets are expanding into new and more vulnerable regions, with harmful patterns of drug use increasing, especially among young people[1].

Financial Trajectory of Illicit Drugs

Revenue and Profit Margins

The financial flows generated by drug trafficking are substantial. For example, the gross profits from cocaine sales were estimated at $84 billion in 2009, with most profits generated in North America and West and Central Europe. Production costs, mainly going to farmers in the Andean region, were significantly lower, around $1 billion[5].

Regional Distribution of Profits

Profits from cocaine sales are distributed across various regions. While the local cocaine market in South America is relatively small, organized crime groups operating in this region generate significant profits by selling drugs both locally and overseas[5].

Impact of Technological Advancements

Decentralized Production and Distribution

Technological advancements have enabled the decentralization of production and distribution networks, complicating efforts to disrupt these illicit activities. Online platforms and cryptocurrencies have facilitated transactions and anonymity, making it harder for law enforcement to track and intercept illicit drug supplies[4].

Emergence of New Substances

The rapid innovation in synthetic drugs, such as fentanyl and its analogues, poses significant challenges to public health systems and law enforcement. These substances are often several times more potent than traditional drugs and have led to a trend towards higher potency across various substance classes[3].

Public Health and Enforcement Challenges

Overdose Crisis

The emergence of fentanyl and other synthetic opioids has led to a severe overdose crisis in North America, with potential implications for other regions, including Europe. The lack of significant improvements in treatment access, preventative approaches, and early warning systems exacerbates this crisis[3].

Regulatory Frameworks

Regulatory frameworks struggle to keep pace with the emergence of new synthetic substances. The UNODC has identified over 1,200 NPS from 141 different countries, highlighting the need for continuous monitoring and adaptation of legal and health responses[4].

Market Adaptation and Resilience

Supplier Adaptation

Drug suppliers have adapted to shifts in the illicit drug landscape by exploiting vulnerabilities in global transport and communications infrastructure. This adaptability reflects a complex and dynamic global economy characterized by technological innovation and the complicity of corrupted individuals and groups[4].

Regional and Global Implications

The global synthetic drug market is influenced by a multitude of factors, including precursor availability, know-how, infrastructure, and the success of local drug enforcement strategies. This complexity necessitates a coordinated global response to address the mortality rates and prevent further harm[3].

Key Takeaways

  • The global illicit drug market is characterized by the rapid expansion of online platforms and the proliferation of synthetic drugs.
  • Cocaine and amphetamine markets are expanding, with record-high production and seizures.
  • Technological advancements have decentralized production and distribution, complicating law enforcement efforts.
  • The emergence of new and potent synthetic substances poses significant public health and enforcement challenges.
  • A coordinated global response is necessary to address the overdose crisis and prevent further harm.

FAQs

What are the key trends in the global illicit drug market?

The key trends include the expansion of online platforms, particularly on the dark web, and the proliferation of synthetic drugs such as fentanyl and its analogues.

How have technological advancements impacted the illicit drug market?

Technological advancements have enabled the decentralization of production and distribution networks, facilitated transactions with cryptocurrencies, and provided anonymity for vendors and buyers.

What are the public health implications of the emerging synthetic drug market?

The emergence of potent synthetic substances like fentanyl has led to a severe overdose crisis, especially in North America, and poses significant challenges to public health systems and law enforcement globally.

How do regulatory frameworks respond to new synthetic substances?

Regulatory frameworks struggle to keep pace with the rapid innovation in synthetic drugs. The UNODC and other agencies continuously monitor and adapt legal and health responses to address the emergence of new substances.

What is the financial impact of illicit drug trafficking?

The financial flows generated by drug trafficking are substantial, with estimated gross profits from cocaine sales alone reaching $84 billion in 2009. Profits are distributed across various regions, with significant amounts generated in North America and West and Central Europe.

Sources

  1. United Nations Office on Drugs and Crime. World Drug Report 2022: Drug Market Trends.
  2. Servier. Servier confirms its 2025 trajectory to achieve its 2030 ambition.
  3. BioMed Central Ltd. Shifting drug markets in North America - a global crisis in the making?
  4. Global Initiative Against Transnational Organized Crime. Global Synthetic Drug Markets: The Present and Future.
  5. United Nations Office on Drugs and Crime. Estimating illicit financial flows resulting from drug trafficking and other transnational organized crimes.

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