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Last Updated: March 29, 2025

LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE Drug Patent Profile


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Which patents cover Lidocaine Hydrochloride W/ Epinephrine, and what generic alternatives are available?

Lidocaine Hydrochloride W/ Epinephrine is a drug marketed by Abbott, Bel Mar, Dell Labs, Intl Medication, and Watson Labs. and is included in eight NDAs.

The generic ingredient in LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE is epinephrine; lidocaine hydrochloride. There are twenty-one drug master file entries for this compound. Eleven suppliers are listed for this compound. Additional details are available on the epinephrine; lidocaine hydrochloride profile page.

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Summary for LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE
US Patents:0
Applicants:5
NDAs:8
Clinical Trials:228
DailyMed Link:LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE at DailyMed
Drug patent expirations by year for LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE
Recent Clinical Trials for LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Montefiore Medical CenterN/A
Jessyka LighthallPhase 3
Assiut UniversityN/A

See all LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE clinical trials

US Patents and Regulatory Information for LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Watson Labs LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE epinephrine; lidocaine hydrochloride INJECTABLE;INJECTION 080377-003 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Bel Mar LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE epinephrine; lidocaine hydrochloride INJECTABLE;INJECTION 080820-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Abbott LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE epinephrine; lidocaine hydrochloride INJECTABLE;INJECTION 083154-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Dell Labs LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE epinephrine; lidocaine hydrochloride INJECTABLE;INJECTION 083389-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Watson Labs LIDOCAINE HYDROCHLORIDE W/ EPINEPHRINE epinephrine; lidocaine hydrochloride INJECTABLE;INJECTION 085463-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 5 of 5 entries

Lidocaine Hydrochloride with Epinephrine: Market Dynamics and Financial Trajectory

Market Overview

Lidocaine hydrochloride, particularly when combined with epinephrine, is a widely used local anesthetic with a broad range of medical applications. The market for lidocaine hydrochloride with epinephrine is driven by several key factors that influence its growth and financial trajectory.

Market Size and Growth

The lidocaine market, which includes lidocaine hydrochloride with epinephrine, has been valued at significant levels and is projected to grow substantially over the forecast period. As of 2023, the lidocaine market was valued at USD 0.89 billion and is expected to grow to USD 1.49 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 5.26% from 2024 to 2032[1].

Key Drivers of Market Growth

Increasing Prevalence of Pain and Chronic Illnesses

The global rise in chronic illnesses and pain-related disorders is a significant driver of the lidocaine market. Chronic diseases, which account for over 60% of yearly mortality and 43% of the global disease burden according to the World Health Organization, are on the rise due to population aging and lifestyle changes[1].

Demand for Non-Opioid Pain Management

The emphasis on non-opioid pain management solutions is another crucial factor. As healthcare professionals seek safer alternatives to opioids, lidocaine hydrochloride with epinephrine gains prominence in the evolving landscape of pain management[1].

Surgical and Cosmetic Procedures

The increasing number of surgical and cosmetic procedures globally also contributes to the market growth. Lidocaine hydrochloride is extensively used in dental procedures, postoperative pain management, and cosmetic surgeries, which are becoming more common[3][4].

Distribution Channels

The lidocaine market is segmented into various distribution channels, with hospital pharmacies and retail pharmacies being the primary segments. Hospital pharmacies dominated the market in 2022 and are expected to be the faster-growing segment during the forecast period, driven by greater client accessibility and lower operating costs. The online distribution channel is also gaining traction, especially post-COVID-19, as patients and healthcare professionals increasingly turn to virtual treatments and online purchases[1][4].

Regional Insights

North America

The North American market is significant, driven by the high volume of surgical procedures, the rising incidence of pain and pain-related illnesses, and the increasing demand for cosmetic procedures. The U.S. is a key market within this region, with a substantial number of dental and cosmetic surgeries contributing to the growth[1].

Asia-Pacific

The Asia-Pacific region is expected to experience the fastest CAGR growth. Countries like China and India are driving this growth due to an increase in dental and cosmetic surgeries, improvements in surgical techniques, and the rising use of lidocaine hydrochloride for postoperative pain treatment[1][4].

Competitive Landscape

The lidocaine market is moderately fragmented with several key players operating globally and regionally. Companies such as Pfizer Inc., Merck KGaA, Astrazeneca Plc, Glenmark Pharmaceuticals, and Teva Pharmaceutical Industries Ltd are actively investing in research and development to expand their product portfolios and enhance their market presence. Strategic partnerships, new product releases, and mergers and acquisitions are common strategies employed by these players to maintain competitiveness[1][3][4].

Impact of COVID-19

The COVID-19 pandemic had a notable impact on the lidocaine market. The potential anesthetic and anti-inflammatory properties of lidocaine made it a candidate for adjunctive treatment in COVID-19 patients, particularly for severe respiratory symptoms. This increased its demand during the pandemic. Post-pandemic, the relaxation of strict regulations on surgical procedures and the resumption of services have further boosted the market growth[3].

Safety and Efficacy

Studies have shown that lidocaine hydrochloride with epinephrine is effective and safe for various medical procedures. For instance, a study comparing the efficacy and safety of 2% lidocaine with different epinephrine concentrations found that the difference in epinephrine concentration does not affect the medical efficacy of the anesthetic, but 2% lidocaine with 1:200,000 epinephrine has better safety regarding hemodynamic parameters[2].

Pharmacokinetics

The pharmacokinetics of lidocaine hydrochloride, especially when combined with epinephrine, have been extensively studied. Adrenaline is known to prolong the duration of local anesthesia and decrease the absorption rate of lidocaine, thereby prolonging its duration of action. This is crucial for procedures requiring extended analgesia[5].

Financial Trajectory

The financial trajectory of the lidocaine hydrochloride market is promising. With a projected CAGR of 5.26% from 2024 to 2032, the market is expected to grow significantly. The increasing demand for safe and effective local anesthetics, coupled with the growing number of surgical and cosmetic procedures, will drive this growth. Here are some key financial projections:

  • Market Size: Expected to grow from USD 0.94 billion in 2024 to USD 1.49 billion by 2032[1].
  • CAGR: 5.26% during the forecast period (2024-2032)[1].
  • Regional Growth: North America and Asia-Pacific regions are expected to drive significant growth, with the latter experiencing the fastest CAGR[1][4].

Key Takeaways

  • The lidocaine hydrochloride market is driven by the increasing prevalence of chronic illnesses and pain-related disorders.
  • The demand for non-opioid pain management solutions and the growing number of surgical and cosmetic procedures are key growth drivers.
  • Hospital pharmacies and online distribution channels are expected to be significant segments.
  • The Asia-Pacific region, particularly China and India, will experience rapid growth.
  • Major industry players are investing heavily in R&D and strategic alliances to maintain market competitiveness.
  • The COVID-19 pandemic has accelerated the use of lidocaine hydrochloride in various medical applications.

FAQs

What is the projected CAGR of the lidocaine hydrochloride market from 2024 to 2032?

The lidocaine hydrochloride market is expected to exhibit a CAGR of 5.26% from 2024 to 2032[1].

Which region is expected to experience the fastest CAGR growth in the lidocaine hydrochloride market?

The Asia-Pacific region is anticipated to experience the fastest CAGR growth during the forecast period[1][4].

How has the COVID-19 pandemic impacted the lidocaine hydrochloride market?

The COVID-19 pandemic increased the demand for lidocaine hydrochloride due to its potential benefits in treating severe respiratory symptoms in COVID-19 patients. Post-pandemic, the relaxation of regulations on surgical procedures has further boosted market growth[3].

What are the primary distribution channels for lidocaine hydrochloride?

The primary distribution channels are hospital pharmacies and retail pharmacies, with online distribution channels gaining traction[1][4].

Which companies are major players in the lidocaine hydrochloride market?

Major companies include Pfizer Inc., Merck KGaA, Astrazeneca Plc, Glenmark Pharmaceuticals, and Teva Pharmaceutical Industries Ltd[1][3][4].

Sources

  1. Market Research Future: Lidocaine Market Analysis
  2. PubMed: Comparison of the efficacy and safety of 2% lidocaine HCl
  3. Mordor Intelligence: Lidocaine Hydrochloride Market Size
  4. Reports and Data: Lidocaine Market Size, Share, Growth, Trends & Forecasts To 2030
  5. PLOS ONE: Pharmacokinetics of Lidocaine Hydrochloride Administered with or without Adrenaline

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