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Last Updated: April 2, 2025

MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER Drug Patent Profile


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Which patents cover Mannitol 10% W/ Dextrose 5% In Distilled Water, and when can generic versions of Mannitol 10% W/ Dextrose 5% In Distilled Water launch?

Mannitol 10% W/ Dextrose 5% In Distilled Water is a drug marketed by B Braun and is included in one NDA.

The generic ingredient in MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER is mannitol. There are eighteen drug master file entries for this compound. Ten suppliers are listed for this compound. Additional details are available on the mannitol profile page.

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Summary for MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER
Drug patent expirations by year for MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER
Recent Clinical Trials for MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER

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SponsorPhase
Washington University School of MedicinePhase 4

See all MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER clinical trials

US Patents and Regulatory Information for MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
B Braun MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER mannitol INJECTABLE;INJECTION 016080-006 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 1 of 1 entries

EU/EMA Drug Approvals for MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER

CompanyDrugnameInnProduct Number / IndicationStatusGenericBiosimilarOrphanMarketing AuthorisationMarketing Refusal
Pharmaxis Europe Limited Bronchitol mannitol EMEA/H/C/001252
Bronchitol is indicated for the treatment of cystic fibrosis (CF) in adults aged 18 years and above as an add-on therapy to best standard of care.
Authorised no no no 2012-04-13
>Company>Drugname>Inn>Product Number / Indication>Status>Generic>Biosimilar>Orphan>Marketing Authorisation>Marketing Refusal
Showing 1 to 1 of 1 entries

Mannitol Market Dynamics and Financial Trajectory

Introduction

Mannitol, a six-carbon sugar alcohol, is widely used in various industries, including pharmaceuticals, food, and beverages. Its unique properties make it a versatile ingredient, particularly as an excipient in pharmaceutical formulations and as a low-calorie sweetener. Here, we delve into the market dynamics and financial trajectory of mannitol, with a focus on its application in medical solutions like Mannitol 10% w/ Dextrose 5% in distilled water.

Market Size and Growth

The global mannitol market has been experiencing significant growth. In 2022, the market size was estimated to be around $418.65 million, and it is projected to reach $890.31 million by 2033, with a Compound Annual Growth Rate (CAGR) of 7.1% from 2023 to 2033[1].

Key Drivers of Growth

Several factors are driving the growth of the mannitol market:

Increasing Health Consciousness

Consumers are becoming more aware of health issues, leading to a higher demand for low-calorie and non-cariogenic sweeteners. Mannitol fits this criteria perfectly, making it a preferred choice in the food and beverage sector[1].

Rising Incidence of Diabetes

The increasing prevalence of diabetes is a significant driver. Mannitol does not cause a significant increase in blood glucose levels, making it an ideal sweetener for diabetic patients. This has led to a surge in its application in the food and beverages sector[1].

Pharmaceutical Applications

Mannitol is extensively used in the pharmaceutical industry as an excipient and for treating various medical conditions such as brain, kidney, and heart problems. Its osmotic diuretic effect makes it crucial in reducing intracranial pressure, intracranial edema, and intraocular pressure[2].

Regional Market Dynamics

Asia-Pacific Region

China is a dominant player in the Asia-Pacific region, accounting for over 52.9% of the market share in 2023. The country's growing food and beverage industry and its status as the world's leading producer of sugar alternatives are key factors driving demand for mannitol[1].

India

India is another significant market, with a market share of more than 47% in the South Asia region. The rising prevalence of diabetes, obesity, and heart disorders in India has increased the demand for alternative sweeteners like mannitol[1].

Product Applications

Medical Solutions

Mannitol 10% w/ Dextrose 5% in distilled water is a common formulation used in medical settings. This solution is administered intravenously and is crucial for its osmotic diuretic effect, which helps in reducing intracranial pressure and treating conditions like cerebral edema and glaucoma[2][5].

Food and Beverages

In the food and beverage sector, mannitol is used as a sweetener in baked goods, confectionery items, and dairy products. Its cooling effect makes it particularly popular in mint-based sweets and gums[1].

Competitive Landscape

The mannitol market is characterized by a mix of global and regional players. Key manufacturers are focusing on expanding their footprint through collaborations with regional players to gain a competitive edge. This strategy is not limited to developing regions but is also seen in developed markets where leading manufacturers are eyeing collaborations to enhance their global reach[1].

Financial Trajectory

Market Value Projections

The global mannitol market is expected to grow significantly, with projected market values increasing from $418.65 million in 2022 to $890.31 million by 2033. The CAGR of 7.1% from 2023 to 2033 indicates a robust financial trajectory for the market[1].

Volume Sales

Volume sales of mannitol are also expected to rise, with shipments projected to reach 66,998 MT in 2023, growing at a rate of 5.62%[1].

Challenges and Considerations

Regulatory Environment

The use of mannitol in various applications is subject to regulatory approvals. For instance, the permission to use sweeteners in bakery, confectionery, and dairy products has been a significant factor in its adoption[1].

Health Risks

While mannitol is generally safe, its administration, especially in medical settings, requires careful monitoring. Excessive loss of water and electrolytes can lead to serious imbalances, and accumulation of mannitol can intensify existing or latent congestive heart failure[5].

Key Takeaways

  • The global mannitol market is projected to grow at a CAGR of 7.1% from 2023 to 2033.
  • Increasing health consciousness and the rising incidence of diabetes are key drivers of growth.
  • Asia-Pacific, particularly China and India, are significant markets due to their growing food and beverage industries and increasing demand for low-calorie sweeteners.
  • Mannitol's application in medical solutions, such as Mannitol 10% w/ Dextrose 5% in distilled water, is crucial for its osmotic diuretic effect.
  • The market is characterized by a mix of global and regional players focusing on collaborations to expand their footprint.

FAQs

Q: What is the projected market size of the global mannitol market by 2033? A: The global mannitol market is projected to reach $890.31 million by 2033[1].

Q: What are the primary drivers of the mannitol market growth? A: The primary drivers include increasing health consciousness, the rising incidence of diabetes, and its extensive use in the pharmaceutical and food industries[1].

Q: Which region dominates the mannitol market? A: The Asia-Pacific region, particularly China, dominates the mannitol market, accounting for over 52.9% of the region's market share in 2023[1].

Q: What are the common medical applications of mannitol? A: Mannitol is used in medical settings for its osmotic diuretic effect, particularly in reducing intracranial pressure, intracranial edema, and intraocular pressure[2][5].

Q: What are the potential health risks associated with mannitol administration? A: Excessive loss of water and electrolytes, accumulation leading to overexpansion of extracellular fluid, and intensification of existing or latent congestive heart failure are potential health risks[5].

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