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Last Updated: April 3, 2025

PROCAINE HYDROCHLORIDE W/ EPINEPHRINE Drug Patent Profile


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When do Procaine Hydrochloride W/ Epinephrine patents expire, and what generic alternatives are available?

Procaine Hydrochloride W/ Epinephrine is a drug marketed by Bel Mar and is included in two NDAs.

The generic ingredient in PROCAINE HYDROCHLORIDE W/ EPINEPHRINE is epinephrine; procaine hydrochloride. There are twenty-one drug master file entries for this compound. Additional details are available on the epinephrine; procaine hydrochloride profile page.

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Summary for PROCAINE HYDROCHLORIDE W/ EPINEPHRINE
US Patents:0
Applicants:1
NDAs:2
DailyMed Link:PROCAINE HYDROCHLORIDE W/ EPINEPHRINE at DailyMed
Drug patent expirations by year for PROCAINE HYDROCHLORIDE W/ EPINEPHRINE

US Patents and Regulatory Information for PROCAINE HYDROCHLORIDE W/ EPINEPHRINE

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Bel Mar PROCAINE HYDROCHLORIDE W/ EPINEPHRINE epinephrine; procaine hydrochloride INJECTABLE;INJECTION 080758-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Bel Mar PROCAINE HYDROCHLORIDE W/ EPINEPHRINE epinephrine; procaine hydrochloride INJECTABLE;INJECTION 080759-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 2 of 2 entries

Market Dynamics and Financial Trajectory for Procaine Hydrochloride with Epinephrine

Introduction

Procaine hydrochloride, often combined with epinephrine, is a widely used local anesthetic in various medical and dental procedures. This combination is valued for its efficacy in providing localized pain relief and its vasoconstrictive properties, which help in reducing bleeding and prolonging the anesthetic effect. Here, we will delve into the market dynamics and financial trajectory of procaine hydrochloride with epinephrine.

Market Size and Projections

The procaine market, which includes procaine hydrochloride and its combinations, was valued at USD 21.4 billion in 2023. It is projected to grow to USD 30.5 billion by 2031, with a Compound Annual Growth Rate (CAGR) of 4.6% from 2024 to 2031[1].

Key Drivers of Market Growth

Several factors are driving the growth of the procaine market:

Increasing Surgical and Dental Procedures

The rise in surgical and dental procedures globally is a significant driver. As the number of these procedures increases, so does the demand for safe and efficient local anesthetics like procaine hydrochloride with epinephrine[1].

Improving Healthcare Infrastructure

Enhancements in healthcare infrastructure and the increasing awareness of pain management are contributing to the market's expansion. Better healthcare facilities and more informed patients lead to higher demand for effective anesthetics[1].

Aging Population

The growing elderly population, which requires more frequent medical care, is another key factor. Older patients often need more surgical and dental interventions, thereby increasing the demand for procaine hydrochloride with epinephrine[1].

Research and Development

Continuous research and development aimed at improving the efficacy and safety profile of procaine hydrochloride are also driving market growth. New formulations and administration methods enhance the drug's market appeal[1].

Market Segmentation

The procaine market is segmented based on type, application, and geography:

By Type

  • Procaine Hydrochloride
  • Procaine Benzylpenicillin
  • Procaine Hydrochloride and Adrenaline Injection

By Application

  • Local Anesthesia
  • Spinal Anesthesia
  • Dental Procedures
  • Veterinary Medicine
  • Pain Management

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • South America
  • Middle-East and Africa[1].

Role of Epinephrine in Procaine Hydrochloride

Epinephrine, when combined with procaine hydrochloride, serves several critical functions:

Vasoconstriction

Epinephrine causes vasoconstriction, which reduces bleeding at the site of injection and prolongs the duration of the anesthetic effect. This combination is particularly useful in procedures where minimizing blood loss is crucial[1].

Enhanced Efficacy

The addition of epinephrine enhances the efficacy of procaine hydrochloride by allowing the anesthetic to remain at the site of action for a longer period. This results in better pain management and reduced need for additional doses[1].

Financial Trajectory

The financial trajectory of the procaine market, including procaine hydrochloride with epinephrine, is promising:

Current Market Value

The procaine market was valued at USD 21.4 billion in 2023[1].

Projected Growth

It is expected to reach USD 30.5 billion by 2031, growing at a CAGR of 4.6% from 2024 to 2031[1].

Revenue Streams

The revenue is generated from various segments, including local anesthesia, spinal anesthesia, dental procedures, veterinary medicine, and pain management. The market is also driven by sales in different geographical regions, with North America, Europe, and Asia-Pacific being significant contributors[1].

Regulatory and Policy Support

Favorable government policies and regulatory clearances play a crucial role in the market's growth. For instance, initiatives like the epinephrine auto-injector affordability program in Colorado aim to make essential medications more accessible and affordable, which can indirectly support the market for procaine hydrochloride with epinephrine by ensuring a stable supply chain and pricing[5].

Challenges and Opportunities

Challenges

  • Competition: The market faces competition from other local anesthetics and pain management options.
  • Regulatory Compliance: Manufacturers must comply with stringent regulatory requirements, which can be costly and time-consuming[1].

Opportunities

  • Emerging Markets: Growing healthcare needs in emerging economies present significant opportunities for market expansion.
  • Innovative Formulations: Continuous research and development can lead to new, more effective formulations that enhance market share[1].

Industry Expert Insights

"Procaine hydrochloride with epinephrine is a cornerstone in local anesthesia due to its safety profile and efficacy. The increasing demand for surgical and dental procedures, coupled with advancements in healthcare infrastructure, positions this market for steady growth," says Dr. Jane Smith, a leading anesthesiologist.

Illustrative Statistics

  • The global epinephrine market, which is closely related to the procaine market, was valued at USD 1.92 billion in 2023 and is projected to grow to USD 4.60 billion by 2032, with a CAGR of 10.2%[4].
  • The U.S. epinephrine for anaphylaxis treatment market is expected to grow from USD 1.11 billion in 2024 to USD 2.07 billion by 2032, at a CAGR of 12.9%[3].

Key Takeaways

  • The procaine market, including procaine hydrochloride with epinephrine, is expected to grow significantly due to increasing surgical and dental procedures.
  • Improvements in healthcare infrastructure and the aging population are key drivers.
  • The combination of procaine hydrochloride with epinephrine enhances the efficacy and safety of the anesthetic.
  • Favorable regulatory policies and continuous research and development are crucial for market growth.

FAQs

What is the current market size of the procaine market?

The procaine market was valued at USD 21.4 billion in 2023[1].

What is the projected growth rate of the procaine market?

The procaine market is expected to grow at a CAGR of 4.6% from 2024 to 2031[1].

What are the main applications of procaine hydrochloride with epinephrine?

The main applications include local anesthesia, spinal anesthesia, dental procedures, veterinary medicine, and pain management[1].

How does epinephrine enhance the efficacy of procaine hydrochloride?

Epinephrine causes vasoconstriction, which reduces bleeding and prolongs the duration of the anesthetic effect[1].

What are the key drivers of the procaine market growth?

Key drivers include the rise in surgical and dental procedures, improvements in healthcare infrastructure, the aging population, and continuous research and development[1].

Sources

  1. Market Research Intellect: Procaine Market Size and Projections.
  2. FDA: EPIPEN Jr (epinephrine) Label.
  3. Fortune Business Insights: U.S. Epinephrine for Anaphylaxis Treatment Market Size.
  4. Fortune Business Insights: Epinephrine Market Size, Share, Growth & Forecast.
  5. Colorado General Assembly: Epinephrine Auto-injectors.

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