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Last Updated: December 22, 2024

NYSTATIN; TRIAMCINOLONE ACETONIDE - Generic Drug Details


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What are the generic sources for nystatin; triamcinolone acetonide and what is the scope of freedom to operate?

Nystatin; triamcinolone acetonide is the generic ingredient in seven branded drugs marketed by Teva, Delcor Asset Corp, Mylan, Cosette, Savage Labs, Alembic, Alpharma Us Pharms, Amneal, Crown Labs Inc, Dr Reddys, Fougera Pharms Inc, Glenmark Pharms Ltd, Lupin Ltd, Macleods Pharms Ltd, Padagis Israel, Perrigo New York, Pharmafair, Taro, Torrent, Pharmaderm, Chartwell Rx, Epic Pharma Llc, Pai Holdings Pharm, Rising, Strides Pharma, and Zydus Lifesciences, and is included in forty-two NDAs. Additional information is available in the individual branded drug profile pages.

Twenty-one suppliers are listed for this compound.

Summary for NYSTATIN; TRIAMCINOLONE ACETONIDE
US Patents:0
Tradenames:7
Applicants:26
NDAs:42
Finished Product Suppliers / Packagers: 21
DailyMed Link:NYSTATIN; TRIAMCINOLONE ACETONIDE at DailyMed
Pharmacology for NYSTATIN; TRIAMCINOLONE ACETONIDE
Anatomical Therapeutic Chemical (ATC) Classes for NYSTATIN; TRIAMCINOLONE ACETONIDE
A01AC Corticosteroids for local oral treatment
A01A STOMATOLOGICAL PREPARATIONS
A01 STOMATOLOGICAL PREPARATIONS
A Alimentary tract and metabolism
A07AA Antibiotics
A07A INTESTINAL ANTIINFECTIVES
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A Alimentary tract and metabolism
C05AA Corticosteroids
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05 VASOPROTECTIVES
C Cardiovascular system
D01AA Antibiotics
D01A ANTIFUNGALS FOR TOPICAL USE
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
D Dermatologicals
D07AB Corticosteroids, moderately potent (group II)
D07A CORTICOSTEROIDS, PLAIN
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D Dermatologicals
D07XB Corticosteroids, moderately potent, other combinations
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D Dermatologicals
G01AA Antibiotics
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G Genito-urinary system and sex hormones
H02AB Glucocorticoids
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H Systemic hormonal preparations, excluding sex hormones and insulins
R01AD Corticosteroids
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01 NASAL PREPARATIONS
R Respiratory system
R03BA Glucocorticoids
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R Respiratory system
S01BA Corticosteroids, plain
S01B ANTIINFLAMMATORY AGENTS
S01 OPHTHALMOLOGICALS
S Sensory organs

US Patents and Regulatory Information for NYSTATIN; TRIAMCINOLONE ACETONIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Padagis Israel NYSTATIN AND TRIAMCINOLONE ACETONIDE nystatin; triamcinolone acetonide CREAM;TOPICAL 208479-001 Aug 14, 2017 AT RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Macleods Pharms Ltd NYSTATIN AND TRIAMCINOLONE ACETONIDE nystatin; triamcinolone acetonide CREAM;TOPICAL 214181-001 Jul 13, 2022 AT RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Cosette MYKACET nystatin; triamcinolone acetonide CREAM;TOPICAL 062367-001 May 28, 1985 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Pharmaderm NYSTATIN TRIAMCINOLONE ACETONIDE nystatin; triamcinolone acetonide CREAM;TOPICAL 062596-001 Oct 8, 1985 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Lupin Ltd NYSTATIN AND TRIAMCINOLONE ACETONIDE nystatin; triamcinolone acetonide CREAM;TOPICAL 208205-001 May 31, 2018 AT RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Pharmaderm NYSTATIN-TRIAMCINOLONE ACETONIDE nystatin; triamcinolone acetonide OINTMENT;TOPICAL 062603-001 Oct 9, 1985 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

NYSTATIN; TRIAMCINOLONE ACETONIDE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Nystatin and Triamcinolone Acetonide

Introduction to Nystatin and Triamcinolone Acetonide

Nystatin and triamcinolone acetonide are two potent medications often combined to treat various skin and fungal infections. Nystatin is an antifungal agent, while triamcinolone acetonide is a synthetic corticosteroid. This combination is widely used to manage conditions such as candidiasis, eczema, dermatitis, and other skin disorders[2][5].

Market Size and Growth Projections

The market for triamcinolone acetonide, which often includes nystatin in combination formulations, is projected to experience significant growth over the coming years.

  • The global triamcinolone market was valued at approximately $874.2 million in 2023 and is anticipated to grow at a CAGR of 3.4% from 2024 to 2032, reaching around $1.2 billion by 2032[4].
  • Another segment, the triamcinolone acetonide nasal market, is expected to grow from $549 million in 2022 to $793.4 million by 2029, with a CAGR of 6.2% during this period[3].

Key Drivers of Market Growth

Several factors are driving the growth of the market for nystatin and triamcinolone acetonide:

Increasing Prevalence of Chronic Diseases

The rising prevalence of chronic inflammatory diseases such as asthma, arthritis, allergies, and various dermatological conditions is a major driver. As the global population ages, the incidence of these conditions increases, leading to higher demand for effective treatments like triamcinolone acetonide[1].

Growing Geriatric Population

The aging population is more prone to chronic and inflammatory diseases due to the natural decline in immune function and cumulative wear and tear on the body's systems. This demographic shift is expected to significantly contribute to the market growth[1].

Advancements in Healthcare Infrastructure

Improvements in healthcare infrastructure, particularly in regions like Asia-Pacific, are enhancing access to healthcare services and driving the demand for triamcinolone acetonide. Countries such as China, Japan, and India are at the forefront of this growth[1].

Regulatory Approvals and Research

The growth in regulatory approvals for new and advanced triamcinolone formulations is increasing the availability and accessibility of these medications, further boosting market growth[4].

Market Segmentation

The market for triamcinolone acetonide is segmented in several ways:

By Type

The market is divided into cream, injections, inhalers, and other types. The cream segment holds a significant market share and is expected to grow at a CAGR of 3.6% over the coming years[4].

By Application

The market is segmented into eczema, dermatitis, allergies, psoriasis, and other applications. The eczema segment dominated the market in 2023, with a revenue of about $377.7 million[4].

By Distribution Channel

The market is segmented into drug stores, hospitals, and online pharmacies. Drug stores secured a leading share of about 66.2% in 2023 and are anticipated to grow at a CAGR of 3.7% during the forecast period[4].

By Region

North America, particularly the U.S., dominates the market due to a large patient population and advanced healthcare systems. The Asia-Pacific region is also experiencing rapid growth, driven by countries like China, Japan, and India[1][4].

Regional Market Outlook

North America

North America, especially the U.S., holds a significant market share due to the high prevalence of chronic conditions and advanced healthcare systems. The U.S. market was valued at $305.9 million in 2023 and is expected to grow at a CAGR of 3.2% over the forecast period[4].

Asia-Pacific

The Asia-Pacific region is experiencing rapid growth due to rising healthcare expenditure, improving medical infrastructure, and increasing awareness about chronic diseases. Countries like China, Japan, and India are driving this growth[1].

Europe

Germany is expected to show significant growth in the triamcinolone market during the forecast period, contributing to the overall European market[4].

Key Market Players

The triamcinolone market is highly fragmented, with several key players including:

  • Lupin
  • Teva Pharmaceuticals
  • Novartis AG
  • Akorn Inc
  • Cosette Pharmaceuticals, Inc
  • Taro Pharmaceutical Industries
  • Sun Pharmaceutical Industries Limited
  • Bristol Myers Squibb Company
  • Mylan N.V.
  • Glenmark Pharmaceuticals[1].

Clinical Pharmacology and Usage

Nystatin

Nystatin exerts its antifungal activity by binding to sterols in the cell membrane of fungi, rendering the cell membrane incapable of functioning as a selective barrier. It is not absorbed from intact skin or mucous membranes[2].

Triamcinolone Acetonide

Triamcinolone acetonide is primarily effective due to its anti-inflammatory, antipruritic, and vasoconstrictive actions. It is used to relieve redness, swelling, itching, and other discomfort associated with skin problems[2][5].

Adverse Reactions and Precautions

The use of nystatin and triamcinolone acetonide combination can lead to adverse reactions such as acneiform eruptions. In children, there is a higher risk of HPA axis suppression, Cushing's syndrome, and intracranial hypertension due to the larger skin surface area to body weight ratio[2].

Financial Trajectory

The financial trajectory of the triamcinolone market, including nystatin combinations, is positive, driven by the increasing demand for effective treatments for chronic and inflammatory diseases.

  • The global triamcinolone market is projected to reach $1.3 billion by 2033, growing at a CAGR of 3.8% from 2024 to 2033[1].
  • The triamcinolone acetonide nasal market is expected to reach $793.4 million by 2029, growing at a CAGR of 6.2%[3].

Illustrative Statistics

  • Healthcare expenditure in Germany rose to about 13.2% of its GDP in 2021, indicating a strong investment in healthcare infrastructure[1].
  • In the U.S., anaphylaxis to food results in around 90,000 emergency room visits each year, highlighting the need for effective treatments like triamcinolone acetonide[1].

Key Takeaways

  • The triamcinolone market, including nystatin combinations, is driven by the increasing prevalence of chronic diseases, growing geriatric population, and advancements in healthcare infrastructure.
  • The market is segmented by type, application, distribution channel, and region, with North America and the Asia-Pacific region being key markets.
  • Key players include major pharmaceutical companies, and the market is expected to grow significantly over the forecast period.
  • The financial trajectory is positive, with projected growth to $1.3 billion by 2033 for the global triamcinolone market.

Frequently Asked Questions

What is the projected market size of the triamcinolone market by 2033?

The global triamcinolone market is projected to reach $1.3 billion by 2033, growing at a CAGR of 3.8% from 2024 to 2033[1].

What are the key drivers of the triamcinolone market growth?

The key drivers include the increasing prevalence of chronic inflammatory diseases, growing geriatric population, and advancements in healthcare infrastructure[1].

Which regions are expected to drive the growth of the triamcinolone market?

North America, particularly the U.S., and the Asia-Pacific region, especially countries like China, Japan, and India, are expected to drive the market growth[1][4].

What are the common applications of nystatin and triamcinolone acetonide combination?

The combination is used to treat fungus infections such as candidiasis and to relieve the discomfort of skin conditions like eczema and dermatitis[2][5].

What are the potential side effects of using nystatin and triamcinolone acetonide combination in children?

Children may experience HPA axis suppression, Cushing's syndrome, and intracranial hypertension due to the larger skin surface area to body weight ratio[2].

Sources:

  1. Allied Market Research - Triamcinolone Market Statistics, Trends | Forecast - 2033
  2. DailyMed - NYSTATIN AND TRIAMCINOLONE ACETONIDE cream
  3. Business Research Insights - Triamcinolone Acetonide Nasal Market Size, Trends, 2024 - 2032
  4. GMI Insights - Triamcinolone Market 2024 – 2032 Industry Growth Report
  5. Mayo Clinic - Nystatin and triamcinolone (topical route) - Mayo Clinic

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