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Last Updated: December 22, 2024

Norepinephrine bitartrate; procaine hydrochloride; propoxycaine hydrochloride - Generic Drug Details


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What are the generic sources for norepinephrine bitartrate; procaine hydrochloride; propoxycaine hydrochloride and what is the scope of freedom to operate?

Norepinephrine bitartrate; procaine hydrochloride; propoxycaine hydrochloride is the generic ingredient in one branded drug marketed by Eastman Kodak and is included in one NDA. Additional information is available in the individual branded drug profile pages.

Summary for norepinephrine bitartrate; procaine hydrochloride; propoxycaine hydrochloride
US Patents:0
Tradenames:1
Applicants:1
NDAs:1
DailyMed Link:norepinephrine bitartrate; procaine hydrochloride; propoxycaine hydrochloride at DailyMed

US Patents and Regulatory Information for norepinephrine bitartrate; procaine hydrochloride; propoxycaine hydrochloride

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Eastman Kodak RAVOCAINE AND NOVOCAIN W/ LEVOPHED norepinephrine bitartrate; procaine hydrochloride; propoxycaine hydrochloride INJECTABLE;INJECTION 008592-003 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Norepinephrine bitartrate; procaine hydrochloride; propoxycaine hydrochloride Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Norepinephrine Bitartrate

Introduction to Norepinephrine Bitartrate

Norepinephrine bitartrate is a pharmaceutical-grade compound widely used in medical settings, particularly for its vasoconstrictive properties. Here, we will delve into the market dynamics, financial trajectory, and key aspects of this drug.

Market Size and Forecast

The global market for Pharmaceutical Grade Norepinephrine Bitartrate is projected to experience significant growth. As of 2023, the market was estimated to be worth US$ 210 million and is forecasted to reach US$ 301.3 million by 2030, with a Compound Annual Growth Rate (CAGR) of 5.3% during the forecast period of 2024-2030[1].

Key Applications

Norepinephrine bitartrate is primarily used in the following applications:

Shock and Hypotension

It is commonly used to treat acute hypotensive states, including those resulting from sepsis, distributive shock, and cardiac arrest. It is the first-line agent for treating hypotension in intensive care units when fluid resuscitation is insufficient[3].

Other Medical Uses

It can also be used in various other medical scenarios, such as in the management of acute myocardial infarction (AMI) with hypotension[4].

Market Segmentation

The market for norepinephrine bitartrate is segmented based on several criteria:

By Type

The market is segmented into purity levels, with categories such as Purity ≥ 99% and Purity < 99%[1].

By Application

The primary applications include injections, particularly for treating shock and hypotension[1][4].

By Region

The market is analyzed across various regions, including North America, Europe, Asia-Pacific, South America, and the Middle East and Africa. The Asia-Pacific region is expected to be one of the fastest-growing markets due to expansive healthcare development and population dynamics[4].

Key Players

Several companies are prominent in the norepinephrine bitartrate market:

  • CAMBREX PROFARMACO MILANO SRL
  • CHEMPACIFIC CORP
  • CURIA NEW YORK INC
  • HARMAN FINOCHEM LTD
  • SUN PHARMACEUTICAL INDUSTRIES LTD
  • Suzhou Yifan Pharmaceutical
  • Wuhan Wuyao Pharmaceutical
  • Shanxi Zhendong Taisheng Pharmaceutical[1].

Market Drivers and Trends

Technological Advancements

The introduction of ready-to-use formulations, such as the premix norepinephrine bitartrate launched by Baxter International Inc., is streamlining medical processes and enhancing safety standards[5].

Increasing Demand for High-Quality Products

There is a growing demand for high-quality and environmentally friendly products in the pharmaceutical sector, driving innovation and investment in the production of norepinephrine bitartrate[2].

Expanding Healthcare Infrastructure

The advancement in healthcare infrastructure, particularly in regions like North America and the Asia-Pacific, is contributing to the increased adoption of norepinephrine bitartrate[5].

Financial Trajectory

The financial trajectory of the norepinephrine bitartrate market is characterized by steady growth. Here are some key financial metrics:

  • Market Size in 2023: US$ 210 million[1].
  • Projected Market Size in 2030: US$ 301.3 million[1].
  • CAGR: 5.3% from 2024 to 2030[1].

Challenges and Restraints

Despite the growth, the market faces several challenges:

Adverse Effects

Norepinephrine can cause adverse effects such as excessive vasoconstriction, decreased end-organ perfusion, and increased pulmonary vascular resistance, which can be detrimental to patients with certain conditions[3].

Regulatory and Compliance Issues

Companies must navigate stringent regulatory requirements and ensure compliance with safety and quality standards, which can be a significant challenge[2].

Conclusion

The market for norepinephrine bitartrate is poised for significant growth driven by its critical applications in treating acute hypotensive states and the increasing demand for high-quality pharmaceutical products. Key players are focusing on technological advancements and expanding their product portfolios to capitalize on this growth.

Key Takeaways

  • The global market for norepinephrine bitartrate is expected to reach US$ 301.3 million by 2030.
  • The primary applications include treating shock and hypotension.
  • Key players are investing in ready-to-use formulations and expanding their product portfolios.
  • The market faces challenges such as adverse effects and regulatory compliance.

FAQs

Q: What is the primary use of norepinephrine bitartrate in medical settings? A: Norepinephrine bitartrate is primarily used as a peripheral vasoconstrictor to treat acute hypotensive states, including those resulting from sepsis and distributive shock[3].

Q: Which region is expected to be the fastest-growing market for norepinephrine bitartrate? A: The Asia-Pacific region is anticipated to be the fastest-growing market due to expansive healthcare development and population dynamics[4].

Q: What are the common adverse effects of norepinephrine? A: The most common adverse effects relate to the activation of alpha1 receptors, including excessive vasoconstriction and decreased end-organ perfusion[3].

Q: Which companies are prominent in the norepinephrine bitartrate market? A: Companies such as CAMBREX PROFARMACO MILANO SRL, CHEMPACIFIC CORP, and SUN PHARMACEUTICAL INDUSTRIES LTD are prominent players in the market[1].

Q: What is the projected CAGR for the norepinephrine bitartrate market from 2024 to 2030? A: The projected CAGR is 5.3% from 2024 to 2030[1].

Sources

  1. Valuates Reports: Pharmaceutical Grade Norepinephrine Bitartrate - Market Report.
  2. Cognitive Market Research: Norepinephrine Bitartrate API Market Report 2024.
  3. NCBI: Norepinephrine - StatPearls.
  4. Market Research Intellect: Norepinephrine Bitartrate Injection Market Size and Forecast.
  5. GlobeNewswire: Global Local Anesthesia Drugs Market Set for Continued Growth.

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