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Last Updated: April 13, 2025

ANCOBON Drug Patent Profile


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When do Ancobon patents expire, and what generic alternatives are available?

Ancobon is a drug marketed by Bausch and is included in one NDA.

The generic ingredient in ANCOBON is flucytosine. There are seven drug master file entries for this compound. Eleven suppliers are listed for this compound. Additional details are available on the flucytosine profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Ancobon

A generic version of ANCOBON was approved as flucytosine by SIGMAPHARM LABS LLC on June 28th, 2011.

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Summary for ANCOBON
Drug patent expirations by year for ANCOBON
Drug Prices for ANCOBON

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Recent Clinical Trials for ANCOBON

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SponsorPhase
University of NairobiPhase 2
Bausch Health Americas, Inc.Phase 2
Yale UniversityPhase 2

See all ANCOBON clinical trials

Pharmacology for ANCOBON

US Patents and Regulatory Information for ANCOBON

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Bausch ANCOBON flucytosine CAPSULE;ORAL 017001-001 Approved Prior to Jan 1, 1982 AB RX Yes No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Bausch ANCOBON flucytosine CAPSULE;ORAL 017001-002 Approved Prior to Jan 1, 1982 AB RX Yes Yes ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 2 of 2 entries

Market Dynamics and Financial Trajectory for ANCOBON (Flucytosine)

Introduction to ANCOBON (Flucytosine)

ANCOBON, also known as flucytosine, is an antifungal agent used primarily in the treatment of serious fungal infections, including cryptococcosis. It is often administered in conjunction with other antifungal drugs like amphotericin B[2][5].

Market Segmentation and Distribution

The market for ANCOBON is segmented based on treatment type, distribution channels, and geographic regions.

Treatment Type

ANCOBON falls under the category of flucytosine, which is a specific type of antifungal treatment. The market for cryptococcosis treatments includes other drugs like amphotericin B, fluconazole, and others (such as voriconazole and surgery treatments)[1].

Distribution Channels

ANCOBON is distributed through various channels, including hospital pharmacies, retail pharmacies, drug stores, mail order pharmacies, and others. Hospital pharmacies and retail pharmacies are significant distribution channels, given the nature of the treatment[1].

Geographic Market Analysis

The global cryptococcosis market, which includes ANCOBON, is analyzed across several regions.

North America

North America accounts for a major share of the global cryptococcosis market. The region's market value forecast by treatment type and distribution channel indicates a steady growth trajectory. The U.S. and Canada are key countries driving this growth[1].

Europe

Europe is another significant region for the cryptococcosis market. Countries like Germany, the U.K., France, Spain, and Italy contribute substantially to the market's growth. The market value forecast by treatment type and distribution channel in these countries shows a positive trend[1].

Asia Pacific

The Asia Pacific region presents substantial growth opportunities due to rising healthcare spending and favorable demographics. Countries such as China, Japan, India, and Australia & New Zealand are key markets for ANCOBON and other cryptococcosis treatments[1][3].

Latin America and Middle East & Africa

Latin America and the Middle East & Africa also offer growth opportunities, driven by increasing healthcare demand and technological advancements. Countries like Brazil and Mexico in Latin America, and various countries in the Middle East & Africa, are important for market expansion[1][3].

Market Growth and Financial Trajectory

The global cryptococcosis market, which includes ANCOBON, is projected to experience significant growth.

Global Market Size and CAGR

The global cryptococcosis market was valued at US$ 4.7 billion in the past and is projected to reach US$ 7.0 billion by 2027, growing at a CAGR of 4.3% during the forecast period[1].

Future Projections

Between 2024 and 2032, the cryptococcosis treatment market is expected to grow further, albeit at a slightly lower CAGR of 2.4%. This growth is driven by increasing demand for healthcare, technological advancements, and the rising prevalence of chronic diseases[3].

Drivers and Challenges

Several factors drive the growth of the ANCOBON market, while others pose challenges.

Drivers

  • Increasing Demand for Healthcare: Rising healthcare needs, especially in developing economies, drive the demand for antifungal treatments like ANCOBON.
  • Technological Advancements: Continued adoption of virtual technologies and expansion of online channels enhance market growth.
  • R&D Activities: Investments in research and development to create modern products that meet evolving customer needs are crucial[3].

Challenges

  • Stringent Regulations: The pharmaceutical industry faces stringent regulatory requirements, which can slow down the approval and launch of new treatments.
  • High R&D Costs: The high costs associated with research and development, along with patent expirations, pose significant challenges for market players[3].

Price Dynamics

Antifungal drugs, including ANCOBON, have experienced significant price increases over the years.

Price Trends

A study on antifungal drug prices in the United States from 2000 to 2019 revealed large, inflation-adjusted price increases. Flucytosine, like other antifungal drugs, has seen moderate to high price increases, influenced by factors such as route of administration and the number of FDA indications[4].

Key Takeaways

  • Market Growth: The global cryptococcosis market, including ANCOBON, is expected to grow significantly, driven by increasing healthcare demand and technological advancements.
  • Geographic Expansion: North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa are key regions for market growth.
  • Distribution Channels: Hospital pharmacies and retail pharmacies are crucial distribution channels for ANCOBON.
  • Challenges: The market faces challenges such as stringent regulations and high R&D costs.
  • Price Dynamics: Antifungal drugs, including ANCOBON, have seen significant price increases over the years.

FAQs

  1. What is ANCOBON used for? ANCOBON (flucytosine) is used to treat serious fungal infections, including cryptococcosis, often in combination with other antifungal drugs like amphotericin B[2][5].

  2. What are the key distribution channels for ANCOBON? The key distribution channels include hospital pharmacies, retail pharmacies, drug stores, mail order pharmacies, and others[1].

  3. What is the projected growth rate of the global cryptococcosis market? The global cryptococcosis market is projected to grow at a CAGR of 4.3% until 2027 and at a CAGR of 2.4% from 2024 to 2032[1][3].

  4. What are the main drivers of the ANCOBON market? The main drivers include increasing demand for healthcare, technological advancements, and the rising prevalence of chronic diseases[3].

  5. What challenges does the ANCOBON market face? The market faces challenges such as stringent regulations, high costs of research and development, and patent expirations[3].

Cited Sources

  1. Transparency Market Research: Cryptococcosis Market | Global Analysis Report 2027
  2. GoodRx: Flucytosine (Ancobon): Uses, Side Effects, Dosage & Reviews
  3. News Channel Nebraska: Cryptococcosis Treatment Market Size 2024-2032: Growth Outlook and Competitive Insights
  4. Wiley Online Library: Antifungal drug price increases in the United States, 2000–2019
  5. FDA: ANCOBON - accessdata.fda.gov

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