DIFFERIN Drug Patent Profile
✉ Email this page to a colleague
Which patents cover Differin, and when can generic versions of Differin launch?
Differin is a drug marketed by Galderma Labs Lp and is included in five NDAs. There are five patents protecting this drug and one Paragraph IV challenge.
This drug has fifty-six patent family members in twenty-two countries.
The generic ingredient in DIFFERIN is adapalene. There are twelve drug master file entries for this compound. Forty suppliers are listed for this compound. Additional details are available on the adapalene profile page.
DrugPatentWatch® Litigation and Generic Entry Outlook for Differin
A generic version of DIFFERIN was approved as adapalene by P AND L on June 2nd, 2010.
AI Research Assistant
Questions you can ask:
- What is the 5 year forecast for DIFFERIN?
- What are the global sales for DIFFERIN?
- What is Average Wholesale Price for DIFFERIN?
Summary for DIFFERIN
International Patents: | 56 |
US Patents: | 5 |
Applicants: | 1 |
NDAs: | 5 |
Finished Product Suppliers / Packagers: | 5 |
Raw Ingredient (Bulk) Api Vendors: | 142 |
Clinical Trials: | 22 |
Patent Applications: | 4,320 |
Drug Prices: | Drug price information for DIFFERIN |
Drug Sales Revenues: | Drug sales revenues for DIFFERIN |
What excipients (inactive ingredients) are in DIFFERIN? | DIFFERIN excipients list |
DailyMed Link: | DIFFERIN at DailyMed |
Recent Clinical Trials for DIFFERIN
Identify potential brand extensions & 505(b)(2) entrants
Sponsor | Phase |
---|---|
Wake Forest University Health Sciences | Early Phase 1 |
Bausch Health Americas, Inc. | Early Phase 1 |
Aurobindo Pharma Ltd | Phase 3 |
Pharmacology for DIFFERIN
Drug Class | Retinoid |
US Patents and Regulatory Information for DIFFERIN
DIFFERIN is protected by five US patents.
Patents protecting DIFFERIN
Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
Patented Use: TOPICAL TREATMENT OF ACNE VULGARIS
Pharmaceutical compositions comprising 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
Cosmetic/dermatological compositions comprising naphthoic acid compounds and polyurethane polymers
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
Patented Use: TREATMENT OF ACNE
Cosmetic/dermatological compositions comprising naphtholic acid compounds and polyurethane polymers
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
Patented Use: TREATMENT OF ACNE
Cosmetic/dermatological compositions comprising naphthoic acid compounds and polyurethane polymers
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
Patented Use: TREATMENT OF ACNE
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Galderma Labs Lp | DIFFERIN | adapalene | CREAM;TOPICAL | 020748-001 | May 26, 2000 | AB | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | ⤷ Sign Up | |||
Galderma Labs Lp | DIFFERIN | adapalene | LOTION;TOPICAL | 022502-001 | Mar 17, 2010 | DISCN | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | |||
Galderma Labs Lp | DIFFERIN | adapalene | GEL;TOPICAL | 021753-001 | Jun 19, 2007 | AB | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | ||
Galderma Labs Lp | DIFFERIN | adapalene | SOLUTION;TOPICAL | 020338-001 | May 31, 1996 | DISCN | Yes | No | ⤷ Sign Up | ⤷ Sign Up | ⤷ Sign Up | ||||
Galderma Labs Lp | DIFFERIN | adapalene | GEL;TOPICAL | 020380-002 | Jul 8, 2016 | OTC | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | ⤷ Sign Up | ||||
Galderma Labs Lp | DIFFERIN | adapalene | GEL;TOPICAL | 021753-001 | Jun 19, 2007 | AB | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | ⤷ Sign Up | |||
Galderma Labs Lp | DIFFERIN | adapalene | LOTION;TOPICAL | 022502-001 | Mar 17, 2010 | DISCN | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | |||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Exclusivity Expiration |
Expired US Patents for DIFFERIN
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
---|---|---|---|---|---|---|---|
Galderma Labs Lp | DIFFERIN | adapalene | GEL;TOPICAL | 021753-001 | Jun 19, 2007 | ⤷ Sign Up | ⤷ Sign Up |
Galderma Labs Lp | DIFFERIN | adapalene | CREAM;TOPICAL | 020748-001 | May 26, 2000 | ⤷ Sign Up | ⤷ Sign Up |
Galderma Labs Lp | DIFFERIN | adapalene | SOLUTION;TOPICAL | 020338-001 | May 31, 1996 | ⤷ Sign Up | ⤷ Sign Up |
Galderma Labs Lp | DIFFERIN | adapalene | GEL;TOPICAL | 021753-001 | Jun 19, 2007 | ⤷ Sign Up | ⤷ Sign Up |
Galderma Labs Lp | DIFFERIN | adapalene | GEL;TOPICAL | 021753-001 | Jun 19, 2007 | ⤷ Sign Up | ⤷ Sign Up |
Galderma Labs Lp | DIFFERIN | adapalene | GEL;TOPICAL | 021753-001 | Jun 19, 2007 | ⤷ Sign Up | ⤷ Sign Up |
Galderma Labs Lp | DIFFERIN | adapalene | GEL;TOPICAL | 021753-001 | Jun 19, 2007 | ⤷ Sign Up | ⤷ Sign Up |
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >Patent No. | >Patent Expiration |
International Patents for DIFFERIN
See the table below for patents covering DIFFERIN around the world.
Country | Patent Number | Title | Estimated Expiration |
---|---|---|---|
Slovenia | 1485080 | ⤷ Sign Up | |
European Patent Office | 1933827 | COMPOSITION CONTENANT AU MOINS UN DERIVE D'ACIDE NAPHTOIQUE ET AU MOINS UN COMPOSE DE TYPE POLYMERE DE POLYURETHANE OU DES DERIVES DE CE COMPOSE, PROCEDES DE FABRICATION ET UTILISATIONS DE CETTE COMPOSITION (COMPOSITION COMPRISING AT LEAST ONE NAPHTHOIC ACID DERIVATIVE AND AT LEAST ONE COMPOUND OF POLYURETHANE POLYMER TYPE OR DERIVATIVES THEREOF, PREPARATION PROCESSES THEREFOR AND USES THEREOF) | ⤷ Sign Up |
European Patent Office | 0199636 | BENZONAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PHARMACY AND COSMETICS | ⤷ Sign Up |
Spain | 554186 | ⤷ Sign Up | |
Norway | 170627 | ⤷ Sign Up | |
Portugal | 82361 | PROCESSO PARA A PREPARACAO DE DERIVADOS BENZONAFTALENICOS E SUA UTILIZACAO NOS DOMINIOS FARMACEUTICOS E COSMETICO | ⤷ Sign Up |
Greece | 860948 | BENZONAPHTALENIC DERIVATIVES METHOD FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL AND COSMETICAL APPLICATIONS | ⤷ Sign Up |
>Country | >Patent Number | >Title | >Estimated Expiration |
Supplementary Protection Certificates for DIFFERIN
Patent Number | Supplementary Protection Certificate | SPC Country | SPC Expiration | SPC Description |
---|---|---|---|---|
1458369 | 08C0024 | France | ⤷ Sign Up | PRODUCT NAME: ADAPALENE - PEROXYDE DE BENZOLE; REGISTRATION NO/DATE IN FRANCE: NL 33724 DU 20080123; REGISTRATION NO/DATE AT EEC: 40440 DU 20071218 |
1458369 | SPC/GB10/005 | United Kingdom | ⤷ Sign Up | PRODUCT NAME: ADAPALENE AND BENZOYL PEROXIDE; REGISTERED: DK 40440 20071218; UK PL10590/0057 20091111 |
0199636 | 300209 | Netherlands | ⤷ Sign Up | 300209, 20060411, EXPIRES: 20070702 |
1458369 | 132008901685368 | Italy | ⤷ Sign Up | PRODUCT NAME: ADAPALENE E BENZOILE PEROSSIDO(EPIDUO); AUTHORISATION NUMBER(S) AND DATE(S): 40440, 20071218;DA 038261018/M A 038261057/M, 20080618 |
>Patent Number | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration | >SPC Description |