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Last Updated: December 22, 2024

NESACAINE Drug Patent Profile


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Which patents cover Nesacaine, and when can generic versions of Nesacaine launch?

Nesacaine is a drug marketed by Fresenius Kabi Usa and is included in one NDA.

The generic ingredient in NESACAINE is chloroprocaine hydrochloride. There are four drug master file entries for this compound. Six suppliers are listed for this compound. Additional details are available on the chloroprocaine hydrochloride profile page.

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Summary for NESACAINE
Drug patent expirations by year for NESACAINE
Drug Prices for NESACAINE

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Recent Clinical Trials for NESACAINE

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SponsorPhase
Johns Hopkins UniversityPhase 3
Oregon Health and Science UniversityEarly Phase 1
Duke UniversityPhase 4

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Pharmacology for NESACAINE
Drug ClassEster Local Anesthetic
Physiological EffectLocal Anesthesia

US Patents and Regulatory Information for NESACAINE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Fresenius Kabi Usa NESACAINE chloroprocaine hydrochloride INJECTABLE;INJECTION 009435-001 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Fresenius Kabi Usa NESACAINE-MPF chloroprocaine hydrochloride INJECTABLE;INJECTION 009435-006 May 2, 1996 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Fresenius Kabi Usa NESACAINE chloroprocaine hydrochloride INJECTABLE;INJECTION 009435-002 Approved Prior to Jan 1, 1982 AP RX Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Fresenius Kabi Usa NESACAINE-MPF chloroprocaine hydrochloride INJECTABLE;INJECTION 009435-003 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

NESACAINE Market Analysis and Financial Projection Experimental

NESACAINE and the Local Anesthesia Drugs Market: Market Dynamics and Financial Trajectory

Introduction to NESACAINE

NESACAINE, also known as chloroprocaine HCl injection, is a local anesthetic used to cause numbness or loss of feeling and prevent pain during certain medical procedures. It is part of a broader category of local anesthesia drugs that are crucial in various surgical and medical settings.

Market Size and Growth of Local Anesthesia Drugs

The global local anesthesia drugs market is anticipated to experience significant growth over the coming years. As of 2023, the market size was valued at USD 4.01 billion and is projected to grow at a CAGR of 3.6% from 2024 to 2030, reaching USD 5.14 billion by 2030[1][4].

Key Drivers of Market Growth

Several factors are driving the growth of the local anesthesia drugs market, including:

Rising Prevalence of Chronic Diseases

The increasing incidence of chronic diseases such as cancer and tumors, which often require intensive and painful treatments, is a significant driver. Local anesthesia helps in making these procedures less traumatic for patients, thereby fueling market growth[3][4].

Growing Geriatric Population

The rise in the geriatric population, who are more prone to chronic diseases and surgeries, is another key factor. By 2050, the proportion of the population above 60 years of age is expected to reach 22%, according to the World Health Organization[4].

Increase in Surgical Procedures

An increase in surgical procedures, including cosmetic surgeries, plastic surgeries, and dental procedures, globally is further expected to foster market growth. The use of local anesthetics in these procedures is widespread and essential[4].

Market Segmentation and NESACAINE's Role

By Product Type

The market is segmented by product type, with lidocaine dominating the market due to its extensive use as both an injectable and topical anesthetic. Chloroprocaine, the active ingredient in NESACAINE, also plays a significant role, particularly in procedures where its rapid onset and short duration of action are beneficial[1][4].

By Application

The market is bifurcated into injectable and surface anesthetics. The injectable segment, which includes NESACAINE, is expected to dominate the market during the forecast period due to its extensive use in various surgical procedures[1][3].

Regional Analysis

North America

North America holds the largest share in the local anesthesia drugs market, driven by a high prevalence of chronic diseases, a growing geriatric population, high per capita income, improved access to healthcare, and advanced healthcare infrastructure. The U.S. has the world's largest market share for anesthesia drugs, which includes NESACAINE[1][3][4].

Competitive Landscape

The local anesthesia drugs market is competitive, with several key players including Aspen Pharmacare, Fresenius Kabi, Novartis, Inc., Sagent Pharmaceutical, Pacira Pharmaceutical, Mylan, and Teva Pharmaceuticals. These companies invest heavily in R&D to develop novel medications and improve existing ones, such as NESACAINE[1][3].

Financial Trajectory

Revenue Projections

The global local anesthesia drugs market, which includes NESACAINE, is projected to generate significant revenue. By 2031, the market is expected to reach $4,724.80 million, growing at a CAGR of 6.4% from 2022 to 2031[3].

Market Share

While specific financial data for NESACAINE is not provided, its inclusion in the broader market indicates that it contributes to the overall revenue and growth. The dominance of injectable anesthetics, which include NESACAINE, suggests a substantial market share for this segment[1][3].

Technological Advancements and Innovations

Advancements in drug delivery systems, such as computer-based local anesthetic delivery and vibrotactile devices, are expected to boost the demand for local anesthetics like NESACAINE. For example, Exparel, a local anesthetic formed by the DepoFoam technology using bupivacaine liposome suspension, highlights the innovative approaches being developed in the field[4].

Regulatory and Safety Considerations

Safety Profile

NESACAINE, like other local anesthetics, has a specific safety profile. It should not be used for lumbar or caudal epidural anesthesia due to safety concerns. Dose selection for elderly patients should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function[2].

Regulatory Environment

The market growth is also influenced by regulatory bodies. Strict regulations imposed on the use of anesthesia drugs can impede market growth, but advancements and approvals of new drugs, such as the FDA approval of new intravenous general anesthetics, can also drive growth[3].

Side Effects and Adverse Reactions

NESACAINE, as with other local anesthetics, can cause various side effects, including central nervous system and cardiovascular system adverse experiences. These are generally dose-related and may include symptoms such as trouble concentrating, trouble sleeping, and unusual tiredness or weakness[2][5].

Conclusion

The local anesthesia drugs market, including NESACAINE, is poised for significant growth driven by the rising prevalence of chronic diseases, an increasing geriatric population, and advancements in drug delivery systems. North America remains a dominant region due to its high healthcare standards and increasing number of surgical procedures.

Key Takeaways

  • The global local anesthesia drugs market is projected to reach USD 5.14 billion by 2030.
  • Lidocaine and other injectable anesthetics dominate the market.
  • North America holds the largest market share due to high healthcare standards and a growing geriatric population.
  • Technological advancements in drug delivery systems are driving market growth.
  • Regulatory and safety considerations are crucial for market dynamics.

FAQs

Q: What is NESACAINE used for?

NESACAINE, or chloroprocaine HCl injection, is used to cause numbness or loss of feeling and prevent pain during certain medical procedures.

Q: What are the key drivers of the local anesthesia drugs market?

The key drivers include the rising prevalence of chronic diseases, a growing geriatric population, and an increase in surgical procedures globally.

Q: Which region dominates the local anesthesia drugs market?

North America dominates the market due to its high prevalence of chronic diseases, growing geriatric population, and advanced healthcare infrastructure.

Q: What are some potential side effects of NESACAINE?

Potential side effects include central nervous system and cardiovascular system adverse experiences, such as trouble concentrating, trouble sleeping, and unusual tiredness or weakness.

Q: How is the market expected to grow in terms of revenue?

The global local anesthesia drugs market is expected to generate revenue of $4,724.80 million by 2031, growing at a CAGR of 6.4% from 2022 to 2031.

Sources

  1. GlobeNewswire - Local Anesthesia Drugs Market Size, Share & Trends Analysis Report 2024-2030.
  2. FDA - NESACAINE (chloroprocaine HCl Injection, USP).
  3. Research Dive - Local Anesthesia Drugs Market Size & Industry Trends: 2031.
  4. Grand View Research - Local Anesthesia Drugs Market Size & Share Report, 2030.
  5. Mayo Clinic - Chloroprocaine (injection route).

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