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Last Updated: December 22, 2024

NESACAINE-MPF Drug Patent Profile


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When do Nesacaine-mpf patents expire, and what generic alternatives are available?

Nesacaine-mpf is a drug marketed by Fresenius Kabi Usa and is included in one NDA.

The generic ingredient in NESACAINE-MPF is chloroprocaine hydrochloride. There are four drug master file entries for this compound. Six suppliers are listed for this compound. Additional details are available on the chloroprocaine hydrochloride profile page.

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Summary for NESACAINE-MPF
US Patents:0
Applicants:1
NDAs:1
Finished Product Suppliers / Packagers: 3
Clinical Trials: 6
DailyMed Link:NESACAINE-MPF at DailyMed
Drug patent expirations by year for NESACAINE-MPF
Recent Clinical Trials for NESACAINE-MPF

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Johns Hopkins UniversityPhase 3
Oregon Health and Science UniversityEarly Phase 1
Duke UniversityPhase 4

See all NESACAINE-MPF clinical trials

Pharmacology for NESACAINE-MPF
Drug ClassEster Local Anesthetic
Physiological EffectLocal Anesthesia

US Patents and Regulatory Information for NESACAINE-MPF

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Fresenius Kabi Usa NESACAINE-MPF chloroprocaine hydrochloride INJECTABLE;INJECTION 009435-003 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Fresenius Kabi Usa NESACAINE-MPF chloroprocaine hydrochloride INJECTABLE;INJECTION 009435-007 May 2, 1996 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Fresenius Kabi Usa NESACAINE-MPF chloroprocaine hydrochloride INJECTABLE;INJECTION 009435-006 May 2, 1996 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

NESACAINE-MPF Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for NESACAINE-MPF

Market Overview

The global local anesthesia drugs market, which includes NESACAINE-MPF, is projected to experience significant growth over the next few years. The market is anticipated to reach USD 5.14 billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 3.6% from 2024 to 2030[1].

Drivers of Market Growth

Several factors are driving the growth of the local anesthesia drugs market, including NESACAINE-MPF:

Increasing Surgical Procedures

The rising number of surgical procedures worldwide, including cosmetic surgeries, dental procedures, and plastic surgeries, is a major driver. Approximately 65% of total surgical procedures require post-operative pain management, which boosts the demand for local anesthesia drugs like NESACAINE-MPF[1].

Advancements in Drug Delivery Systems

Advancements in drug delivery systems are expected to drive the market for surface anesthetics, which includes formulations like NESACAINE-MPF. These advancements enhance the efficacy and safety of local anesthetics, making them more appealing to healthcare providers[1].

Rising Healthcare Expenditure

Increasing healthcare expenditure in developing countries such as India, China, and Brazil is expected to result in a higher number of surgeries performed in these regions. This trend is likely to contribute to the growth of the local anesthesia drugs market, including NESACAINE-MPF[1].

Market Segmentation

By Product

NESACAINE-MPF, which contains chloroprocaine, falls under the category of local anesthetics. Lidocaine has historically dominated the market, but other drugs like bupivacaine, ropivacaine, and chloroprocaine are gaining traction due to their effectiveness and specific use cases[1].

By Application

The market is bifurcated into injectable and surface anesthetics. The injectable segment, which includes NESACAINE-MPF, is expected to dominate the market during the forecast period due to its extensive use in various surgical procedures[1].

Regional Insights

North America

North America holds the largest share in the local anesthesia drugs market, driven by a significant number of surgical procedures performed in the region. This makes it a key market for NESACAINE-MPF and other local anesthetics[1].

Asia Pacific

The Asia Pacific region is expected to see substantial growth due to increasing healthcare expenditure and a rising number of surgical procedures in countries like India, China, and Brazil[1].

Competitive Landscape

NESACAINE-MPF is part of a competitive market with several key players, including Aspen Pharmacare, Fresenius Kabi, Novartis, Inc., Sagent Pharmaceutical, Pacira Pharmaceutical, Mylan, and Teva Pharmaceuticals. These companies are continuously innovating and expanding their product portfolios to capture market share[1].

Product Specifics

Indications and Usage

NESACAINE-MPF is indicated for the production of local anesthesia by infiltration, peripheral nerve block, and central nerve block, including lumbar and caudal epidural blocks. It is available in various formulations, such as 2% and 3% solutions, and is administered under the supervision of experienced clinicians[3][4].

Dosage and Administration

The dosage of NESACAINE-MPF varies based on the procedure and patient condition. For example, the maximum single recommended dose is 11mg/kg, not to exceed a total dose of 800mg. Doses need to be adjusted for debilitated, elderly, or acutely ill patients[3][4].

Contraindications and Warnings

NESACAINE-MPF is contraindicated in patients hypersensitive to drugs of the PABA ester group. It should be used with caution in patients with existing neurological disease, spinal deformities, septicemia, severe hypertension, and other specific medical conditions[3][4].

Financial Trajectory

Given the overall growth of the local anesthesia drugs market, NESACAINE-MPF is likely to contribute significantly to the financial performance of its manufacturers. Here are some key financial insights:

Market Size and Growth

The global local anesthesia drugs market is projected to grow from USD 4.01 billion in 2023 to USD 5.14 billion by 2030, indicating a steady increase in demand and revenue potential for products like NESACAINE-MPF[1].

Revenue Contribution

As part of the injectable anesthetics segment, which is expected to dominate the market, NESACAINE-MPF will likely contribute a substantial portion of the revenue for its manufacturers. The specific revenue contribution will depend on market share, pricing, and the adoption rate of the drug in various regions[1].

Key Takeaways

  • The global local anesthesia drugs market is growing, driven by increasing surgical procedures and advancements in drug delivery systems.
  • NESACAINE-MPF is a key player in the injectable anesthetics segment, with specific indications and usage guidelines.
  • The drug's market performance will be influenced by regional healthcare expenditure, competitive landscape, and its safety and efficacy profile.
  • Manufacturers need to be cautious about contraindications and warnings associated with NESACAINE-MPF to ensure safe and effective use.

FAQs

Q: What is the projected market size for local anesthesia drugs by 2030? A: The global local anesthesia drugs market is anticipated to reach USD 5.14 billion by 2030[1].

Q: What are the primary drivers of the local anesthesia drugs market? A: The rising number of surgical procedures, advancements in drug delivery systems, and increasing healthcare expenditure in developing countries are key drivers[1].

Q: What are the common indications for NESACAINE-MPF? A: NESACAINE-MPF is indicated for the production of local anesthesia by infiltration, peripheral nerve block, and central nerve block, including lumbar and caudal epidural blocks[3][4].

Q: What are the contraindications for NESACAINE-MPF? A: NESACAINE-MPF is contraindicated in patients hypersensitive to drugs of the PABA ester group and should be used with caution in patients with specific medical conditions[3][4].

Q: Which region holds the largest share in the local anesthesia drugs market? A: North America holds the largest share in the local anesthesia drugs market due to a significant number of surgical procedures performed in the region[1].

Cited Sources

  1. GlobeNewswire: Local Anesthesia Drugs Market Size, Share & Trends Analysis 2024-2030.
  2. CU Denver: CRASH 2015 TABLE OF CONTENT.
  3. eMPR.com: NESACAINE-MPF Prescription & Dosage Information.
  4. FDA: Nesacaine® (chloroprocaine HCl Injection, USP) Label.
  5. Mayo Clinic: Chloroprocaine (injection route).

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