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Last Updated: December 25, 2024

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TYBOST Drug Patent Profile


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When do Tybost patents expire, and what generic alternatives are available?

Tybost is a drug marketed by Gilead Sciences Inc and is included in one NDA. There are two patents protecting this drug and one Paragraph IV challenge.

This drug has two hundred and ninety-five patent family members in forty countries.

The generic ingredient in TYBOST is cobicistat. There are five drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the cobicistat profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Tybost

A generic version of TYBOST was approved as cobicistat by MYLAN LABS LTD on February 7th, 2024.

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Drug patent expirations by year for TYBOST
Drug Prices for TYBOST

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Recent Clinical Trials for TYBOST

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Maastricht University Medical CenterPhase 4
Pyramid BiosciencesPhase 1
Bristol-Myers SquibbPhase 1

See all TYBOST clinical trials

Paragraph IV (Patent) Challenges for TYBOST
Tradename Dosage Ingredient Strength NDA ANDAs Submitted Submissiondate
TYBOST Tablets cobicistat 150 mg 203094 1 2016-11-14

US Patents and Regulatory Information for TYBOST

TYBOST is protected by two US patents and one FDA Regulatory Exclusivity.

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Gilead Sciences Inc TYBOST cobicistat TABLET;ORAL 203094-001 Sep 24, 2014 AB RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y ⤷  Subscribe
Gilead Sciences Inc TYBOST cobicistat TABLET;ORAL 203094-001 Sep 24, 2014 AB RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y ⤷  Subscribe
Gilead Sciences Inc TYBOST cobicistat TABLET;ORAL 203094-001 Sep 24, 2014 AB RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for TYBOST

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Gilead Sciences Ireland UC Tybost cobicistat EMEA/H/C/002572
Tybost is indicated as a pharmacokinetic enhancer of atazanavir 300 mg once daily or darunavir 800 mg once daily as part of antiretroviral combination therapy in human immunodeficiency virus-1 (HIV-1) infected adults and adolescents aged 12 years and older:weighing at least 35 kg co‑administered with atazanavir orweighing at least 40 kg co‑administered with darunavir.
Authorised no no no 2013-09-19
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

International Patents for TYBOST

When does loss-of-exclusivity occur for TYBOST?

Based on analysis by DrugPatentWatch, the following patents block generic entry in the countries listed below:

African Regional IP Organization (ARIPO)

Patent: 89
Patent: The use of solid carrier particles to improve the processability of a pharmaceutical agent
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Patent: 50
Patent: Tablets for combination therapy
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Argentina

Patent: 5369
Patent: COMPRIMIDOS PARA TERAPIA DE COMBINACION PARA EL TRATAMIENTO DE INFECCIONES VIRALES.
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Australia

Patent: 09242451
Patent: The use of solid carrier particles to improve the processability of a pharmaceutical agent
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Patent: 10210598
Patent: Tablets for combination therapy
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Patent: 14221210
Estimated Expiration: ⤷  Subscribe

Patent: 15200637
Patent: TABLETS FOR COMBINATION THERAPY
Estimated Expiration: ⤷  Subscribe

Patent: 16250470
Patent: THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT
Estimated Expiration: ⤷  Subscribe

Patent: 17201473
Patent: Tablets for combination therapy
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Patent: 18267573
Patent: Tablets for combination therapy
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Brazil

Patent: 0911871
Patent: uso de partículas veículo sólidas para melhorar a processabilidade de um agente farmacêutico
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Patent: 1008664
Patent: comprimidos para a terapia de combinação
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Canada

Patent: 20856
Patent: UTILISATION DE PARTICULES SUPPORTS SOLIDES POUR AMELIORER L'APTITUDE AU TRAITEMENT D'UN AGENT PHARMACEUTIQUE (THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT)
Estimated Expiration: ⤷  Subscribe

Patent: 50521
Patent: PASTILLES DESTINEES A UNE THERAPIE COMBINEE (TABLETS FOR COMBINATION THERAPY)
Estimated Expiration: ⤷  Subscribe

Chile

Patent: 11001885
Patent: Tableta bicapa oral en donde la primera capa comprende al compuesto de formula i (elvitegravir) y al compuesto de formula ii, y la segunda capa comprende al compuesto de formula iii (emtricitabina) y a la sal de formula iv (sal de tenofovir); metodo para la preparacion, util en el tratar infecciones por vih.
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China

Patent: 2123700
Patent: The use of solid carrier particles to improve the processability of a pharmaceutical agent
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Patent: 2307573
Patent: Tablets for combination therapy
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Patent: 3479584
Patent: Use of solid carrier particles to improve the processability of pharmaceutical agent
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Patent: 4940937
Patent: The use of solid carrier particles to improve the processability of a pharmaceutical agent
Estimated Expiration: ⤷  Subscribe

Colombia

Patent: 21225
Patent: PARTICULAS PORTADORAS SÓLIDAS PARA MEJORAR LA PROCESABILIDAD DE UN AGENTE FARMACÉUTICO
Estimated Expiration: ⤷  Subscribe

Patent: 00187
Patent: TABLETAS PARA TERAPIA DE COMBINACIÓN
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Croatia

Patent: 0151009
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Patent: 0151357
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Cyprus

Patent: 16852
Estimated Expiration: ⤷  Subscribe

Patent: 17067
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Denmark

Patent: 96633
Estimated Expiration: ⤷  Subscribe

Patent: 93485
Estimated Expiration: ⤷  Subscribe

Ecuador

Patent: 10010636
Patent: EL USO DE PARTÍCULAS TRANSPORTADORAS SÓLIDAS PARA MEJORAR LA PROCESABILIDAD DE UN AGENTE FARMACÉUTICO
Estimated Expiration: ⤷  Subscribe

Patent: 11011307
Patent: COMPRIMIDOS PARA TERAPIA DE COMBINACION
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Eurasian Patent Organization

Patent: 1313
Patent: ТАБЛЕТКИ ДЛЯ КОМБИНИРОВАННОЙ ТЕРАПИИ (TABLETS FOR COMBINATION THERAPY)
Estimated Expiration: ⤷  Subscribe

Patent: 2950
Patent: ПРИМЕНЕНИЕ ЧАСТИЦ НОСИТЕЛЯ ДИОКСИДА КРЕМНИЯ ДЛЯ УЛУЧШЕНИЯ ТЕХНОЛОГИЧЕСКИХ ХАРАКТЕРИСТИК ФАРМАЦЕВТИЧЕСКОГО АГЕНТА (USE OF SILICON DIOXIDE CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT)
Estimated Expiration: ⤷  Subscribe

Patent: 0123
Patent: ТАБЛЕТКА ДЛЯ ЛЕЧЕНИЯ ВИЧ И СПОСОБ ЛЕЧЕНИЯ ВИЧ С ЕЕ ПРИМЕНЕНИЕМ (TABLET FOR TREATING HIV AND METHOD OF TREATING HIV USING SAME)
Estimated Expiration: ⤷  Subscribe

Patent: 1071173
Patent: ПРИМЕНЕНИЕ ЧАСТИЦ ТВЁРДОГО НОСИТЕЛЯ ДЛЯ УЛУЧШЕНИЯ ТЕХНОЛОГИЧЕСКИХ ХАРАКТЕРИСТИК ФАРМАЦЕВТИЧЕСКОГО АГЕНТА
Estimated Expiration: ⤷  Subscribe

Patent: 1190125
Patent: ТАБЛЕТКИ ДЛЯ КОМБИНИРОВАННОЙ ТЕРАПИИ
Estimated Expiration: ⤷  Subscribe

Patent: 1491658
Patent: ТАБЛЕТКИ ДЛЯ КОМБИНИРОВАННОЙ ТЕРАПИИ
Estimated Expiration: ⤷  Subscribe

Patent: 1591353
Patent: ПРИМЕНЕНИЕ ЧАСТИЦ ТВЕРДОГО НОСИТЕЛЯ ДЛЯ УЛУЧШЕНИЯ ТЕХНОЛОГИЧЕСКИХ ХАРАКТЕРИСТИК ФАРМАЦЕВТИЧЕСКОГО АГЕНТА
Estimated Expiration: ⤷  Subscribe

European Patent Office

Patent: 96633
Patent: UTILISATION DE VEHICULES PARTICULAIRES SOLIDES POUR FACILITER LA FORMULATION D'UN AGENT PHARMACEUTIQUE. (THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT)
Estimated Expiration: ⤷  Subscribe

Patent: 93485
Patent: COMPRIMÉ BICOUCHE CONTENANT DE L'ELVITEGRAVIR, DU COBICISTAT, DE L'EMTRICITABINE ET DU TENOFOVIR (BILAYER TABLETS COMPRISING ELVITEGRAVIR, COBICISTAT, EMTRICITABINE AND TENOFOVIR)
Estimated Expiration: ⤷  Subscribe

Patent: 06032
Patent: UTILISATION DE PARTICULES SUPPORTS SOLIDES POUR AMÉLIORER L'APTITUDE AU TRAITEMENT D'UN AGENT PHARMACEUTIQUE (THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT)
Estimated Expiration: ⤷  Subscribe

Hong Kong

Patent: 53670
Patent: 利用固體載體顆粒來改進藥劑加工性 (THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT)
Estimated Expiration: ⤷  Subscribe

Patent: 64737
Patent: 包括埃替拉韋, ,恩曲他濱和替諾福韋的雙層片劑 (BILAYER TABLETS COMPRISING ELVITEGRAVIR, COBICISTAT, EMTRICITABINE AND TENOFOVIR COBICISTAT)
Estimated Expiration: ⤷  Subscribe

Patent: 15679
Patent: 固體載體顆粒在改善藥物製劑加工性中的應用 (THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT)
Estimated Expiration: ⤷  Subscribe

Hungary

Patent: 25822
Estimated Expiration: ⤷  Subscribe

Patent: 26380
Estimated Expiration: ⤷  Subscribe

Israel

Patent: 8614
Patent: שימוש בחלקיקי נשא מוצק לשיפור היכולת לעיבוד חומר רוקחי (Use of solid carrier particles to improve the processability of a pharmaceutical agent)
Estimated Expiration: ⤷  Subscribe

Patent: 4227
Patent: טבליות עבור טיפול משולב (Tablets for combination therapy)
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Japan

Patent: 11242
Estimated Expiration: ⤷  Subscribe

Patent: 22213
Estimated Expiration: ⤷  Subscribe

Patent: 11927
Estimated Expiration: ⤷  Subscribe

Patent: 25171
Estimated Expiration: ⤷  Subscribe

Patent: 11522790
Estimated Expiration: ⤷  Subscribe

Patent: 12517432
Estimated Expiration: ⤷  Subscribe

Patent: 14012741
Patent: USE OF SOLID CARRIER PARTICLE TO IMPROVE PROCESSABILITY OF PHARMACEUTICAL AGENT
Estimated Expiration: ⤷  Subscribe

Patent: 14221845
Patent: 併用治療のための錠剤 (TABLETS FOR COMBINATION THERAPY)
Estimated Expiration: ⤷  Subscribe

Mexico

Patent: 2377
Patent: USO DE PARTICULAS TRASPORTADORAS SOLIDAS PARA MEJORAR LA CAPACIDAD DE PROCESAMIENTO DE UN AGENTE FARMACEUTICO. (THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT.)
Estimated Expiration: ⤷  Subscribe

Patent: 10011963
Patent: USO DE PARTICULAS TRASPORTADORAS SOLIDAS PARA MEJORAR LA CAPACIDAD DE PROCESAMIENTO DE UN AGENTE FARMACEUTICO. (THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT.)
Estimated Expiration: ⤷  Subscribe

Patent: 11008289
Patent: TABLETAS PARA TERAPIA COMBINADA. (TABLETS FOR COMBINATION THERAPY.)
Estimated Expiration: ⤷  Subscribe

New Zealand

Patent: 8978
Patent: THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT
Estimated Expiration: ⤷  Subscribe

Patent: 4214
Patent: TABLETS COMPRISING COBICISTAT, ELVITEGRAVIR, EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE FOR COMBINATION THERAPY
Estimated Expiration: ⤷  Subscribe

Peru

Patent: 110994
Patent: COMPRIMIDOS ANTIVIRALES QUE COMPRENDEN ELVITEGRAVIR, EMTRICITABINA, DISOPROXIL FUMARATO DE TENOFOVIR Y UN DERIVADO DE TIAZOL
Estimated Expiration: ⤷  Subscribe

Poland

Patent: 96633
Estimated Expiration: ⤷  Subscribe

Patent: 93485
Estimated Expiration: ⤷  Subscribe

Portugal

Patent: 96633
Estimated Expiration: ⤷  Subscribe

Patent: 93485
Estimated Expiration: ⤷  Subscribe

San Marino

Patent: 01500266
Patent: COMPRESSE A DOPPIO STRATO COMPRENDENTI ELVITEGRAVIR, COBICISTAT, EMTRICITABINA E TENOFOVIR
Estimated Expiration: ⤷  Subscribe

Singapore

Patent: 3544
Patent: TABLETS FOR COMBINATION THERAPY
Estimated Expiration: ⤷  Subscribe

Patent: 0618
Patent: THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT
Estimated Expiration: ⤷  Subscribe

Patent: 14007744
Patent: TABLETS FOR COMBINATION THERAPY
Estimated Expiration: ⤷  Subscribe

Patent: 201609006W
Patent: THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT
Estimated Expiration: ⤷  Subscribe

Patent: 201706215U
Patent: Tablets for combination therapy
Estimated Expiration: ⤷  Subscribe

Slovenia

Patent: 96633
Estimated Expiration: ⤷  Subscribe

Patent: 93485
Estimated Expiration: ⤷  Subscribe

South Africa

Patent: 1008007
Patent: THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT
Estimated Expiration: ⤷  Subscribe

South Korea

Patent: 1645759
Estimated Expiration: ⤷  Subscribe

Patent: 1659971
Estimated Expiration: ⤷  Subscribe

Patent: 1738325
Estimated Expiration: ⤷  Subscribe

Patent: 1784647
Estimated Expiration: ⤷  Subscribe

Patent: 110015581
Patent: THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT
Estimated Expiration: ⤷  Subscribe

Patent: 110122729
Patent: TABLETS FOR COMBINATION THERAPY
Estimated Expiration: ⤷  Subscribe

Patent: 160093100
Patent: 조합 요법용 정제 (TABLETS FOR COMBINATION THERAPY)
Estimated Expiration: ⤷  Subscribe

Patent: 160114728
Patent: 제약 제제의 가공성 향상을 위한 고체 담체 입자의 용도 (THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT)
Estimated Expiration: ⤷  Subscribe

Spain

Patent: 48886
Estimated Expiration: ⤷  Subscribe

Patent: 53897
Estimated Expiration: ⤷  Subscribe

Taiwan

Patent: 44367
Estimated Expiration: ⤷  Subscribe

Patent: 1040142
Patent: Tablets for combination therapy
Estimated Expiration: ⤷  Subscribe

Ukraine

Patent: 1193
Patent: ПРИМЕНЕНИЕ ЧАСТИЧЕК ТВЕРДОГО НОСИТЕЛЯ ДЛЯ УЛУЧШЕНИЯ ТЕХНОЛОГИЧЕСКИХ ХАРАКТЕРИСТИК ФАРМАЦЕВТИЧЕСКОГО АГЕНТА;ЗАСТОСУВАННЯ ЧАСТИНОК ТВЕРДОГО НОСІЯ ДЛЯ ПОЛІПШЕННЯ ТЕХНОЛОГІЧНИХ ХАРАКТЕРИСТИК ФАРМАЦЕВТИЧНОГО АГЕНТА (THE USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT)
Estimated Expiration: ⤷  Subscribe

Patent: 3224
Patent: ТАБЛЕТКИ ДЛЯ КОМБИНИРОВАННОЙ ТЕРАПИИ;ТАБЛЕТКИ ДЛЯ КОМБІНОВАНОЇ ТЕРАПІЇ (Normal;heading 1;heading 2;heading 3;TABLETS FOR COMBINATION THERAPY)
Estimated Expiration: ⤷  Subscribe

Uruguay

Patent: 424
Patent: COMPRIMIDOS CONTENIENDO ELIVITEGRAVIR PARA TRATAMIENTO DE INFECCIONES VIRALES
Estimated Expiration: ⤷  Subscribe

Generics may enter earlier, or later, based on new patent filings, patent extensions, patent invalidation, early generic licensing, generic entry preferences, and other factors.

See the table below for additional patents covering TYBOST around the world.

Country Patent Number Title Estimated Expiration
Lithuania C2487163 ⤷  Subscribe
Eurasian Patent Organization 021313 ТАБЛЕТКИ ДЛЯ КОМБИНИРОВАННОЙ ТЕРАПИИ (TABLETS FOR COMBINATION THERAPY) ⤷  Subscribe
Spain 2796275 ⤷  Subscribe
>Country >Patent Number >Title >Estimated Expiration

Supplementary Protection Certificates for TYBOST

Patent Number Supplementary Protection Certificate SPC Country SPC Expiration SPC Description
2487166 2016/061 Ireland ⤷  Subscribe PRODUCT NAME: COBICISTAT OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND TENOFOVIR ALAFENAMIDE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, IN PARTICULAR TENOFOVIR ALAFENAMIDE FUMARATE; REGISTRATION NO/DATE: EU/1/15/1061 20151119
2487166 93354 Luxembourg ⤷  Subscribe PRODUCT NAME: COBICISTAT OU UN SEL PHARMACEUTIQUEMENT ACCEPTABLE DE CELUI-CI ET ALAFENAMIDE DE TENOFOVIR OU UN SEL PHARMACEUTIQUEMENT ACCEPTABLE DE CELUI-CI, EN PARTICULIER LE FUMARATE D'ALAFENAMIDE DE TENOFOVIR; AUTHORISATION NUMBER AND DATE: EU/1/15/1061
2487166 300860 Netherlands ⤷  Subscribe PRODUCT NAME: COBICISTAT, DAN WEL EEN FARMACEUTISCH AANVAARDBAAR ZOUT DAARVAN EN TENOFOVIR-ALAFENAMIDE, DAN WEL EEN FARMACEUTISCH AANVAARDBAAR ZOUT DAARVAN, IN HET BIJZONDER TENOFOVIR-ALAFENAMIDEFUMARAAT; REGISTRATION NO/DATE: EU/1/15/1061 20151123
>Patent Number >Supplementary Protection Certificate >SPC Country >SPC Expiration >SPC Description

TYBOST Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for TYBOST

Introduction to TYBOST

TYBOST, also known as cobicistat, is a CYP3A inhibitor used in combination with other antiretroviral agents to treat HIV-1 infection in adults and pediatric patients. It is manufactured by Gilead Sciences and plays a crucial role in the HIV treatment regimen by increasing the systemic exposure of atazanavir or darunavir.

Indications and Usage

TYBOST is indicated for use in combination with atazanavir or darunavir, once daily, to treat HIV-1 infection. It is used in both adult and pediatric patients, with specific weight requirements for pediatric use[4].

Market Positioning

TYBOST is part of Gilead Sciences' extensive HIV treatment portfolio, which includes other prominent drugs like Biktarvy, Descovy, and Truvada. The HIV market is highly competitive, but Gilead's products have maintained a strong presence due to their efficacy and market acceptance.

Financial Performance of Gilead Sciences' HIV Portfolio

In the full year 2023, Gilead Sciences' HIV product sales increased by 6% year-over-year (YoY) to $18.2 billion, driven by higher demand and favorable channel inventory dynamics. This growth was largely attributed to the performance of Biktarvy and Descovy, which are often used in conjunction with TYBOST[1].

Biktarvy and Descovy Sales

  • Biktarvy sales increased by 14% YoY to $11.8 billion in 2023, reflecting higher demand and higher average realized prices.
  • Descovy sales increased by 6% YoY to $2.0 billion in 2023, driven by favorable channel inventory dynamics and higher demand[1].

TYBOST Sales Integration

While specific sales figures for TYBOST are not separately reported, its contribution is integral to the overall HIV product sales. TYBOST is often co-administered with other antiretroviral agents like atazanavir and darunavir, which are part of the broader HIV treatment regimen.

Market Trends and Demand

The HIV treatment market has seen consistent growth driven by increasing demand for antiretroviral therapies (ART) and pre-exposure prophylaxis (PrEP). Gilead Sciences has maintained a strong market share in the U.S. and globally, with its HIV products commanding a significant portion of the market.

U.S. Market Share

Gilead Sciences' U.S. market share for HIV treatments remained robust, with a market share of approximately 48% in 2023. The company also saw a 3% YoY growth in U.S. market share[3].

Pricing Dynamics

Pricing dynamics play a crucial role in the sales performance of TYBOST and other HIV drugs. In the fourth quarter of 2023, HIV product sales were affected by lower average realized prices due to channel mix, although this was partially offset by higher demand and favorable inventory dynamics[1].

Competitive Landscape

The HIV treatment market is highly competitive, with several pharmaceutical companies offering various antiretroviral therapies. However, Gilead Sciences' portfolio, including TYBOST, has maintained a strong competitive edge due to its efficacy, safety profile, and established market presence.

Regulatory and Safety Considerations

TYBOST, like other antiretroviral agents, is subject to regulatory oversight and safety monitoring. It has been associated with renal adverse events, particularly when co-administered with tenofovir disoproxil fumarate (TDF), and requires careful monitoring of renal function in patients[2][4].

Future Outlook

The future outlook for TYBOST and Gilead Sciences' HIV portfolio remains positive, driven by ongoing demand for effective HIV treatments and the company's continued innovation in the field. However, the market will continue to be influenced by factors such as pricing dynamics, regulatory changes, and the introduction of new therapies.

Growth Projections

Gilead Sciences anticipates continued growth in its HIV business, with a focus on maintaining market leadership through strong demand for its products and strategic partnerships. The company's overall product sales, excluding Veklury, increased by 7% in 2023, and this trend is expected to continue in the coming years[1].

Key Takeaways

  • TYBOST is a critical component of Gilead Sciences' HIV treatment portfolio.
  • The drug's sales are integrated within the broader HIV product sales, which saw a 6% YoY increase in 2023.
  • Pricing dynamics and channel mix can impact sales, but overall demand for HIV treatments remains strong.
  • Regulatory and safety considerations are crucial for the continued use of TYBOST.
  • The future outlook for TYBOST and Gilead's HIV portfolio is positive, driven by ongoing demand and innovation.

FAQs

1. What is TYBOST used for?

TYBOST is used as a CYP3A inhibitor to increase the systemic exposure of atazanavir or darunavir in the treatment of HIV-1 infection in adults and pediatric patients[4].

2. How does TYBOST contribute to Gilead Sciences' financial performance?

TYBOST contributes to Gilead Sciences' financial performance as part of the company's broader HIV treatment portfolio, which saw a 6% YoY increase in sales in 2023[1].

3. What are the potential side effects of TYBOST?

TYBOST can cause renal adverse events, particularly when co-administered with TDF, and may lead to increases in serum creatinine and decreases in estimated creatinine clearance[2][4].

4. How does the competitive landscape affect TYBOST sales?

The competitive landscape in the HIV treatment market is highly competitive, but Gilead Sciences' portfolio, including TYBOST, maintains a strong competitive edge due to its efficacy and established market presence.

5. What is the future outlook for TYBOST and Gilead Sciences' HIV portfolio?

The future outlook is positive, driven by ongoing demand for effective HIV treatments and Gilead Sciences' continued innovation in the field. The company anticipates continued growth in its HIV business[1].

Cited Sources:

  1. Gilead Sciences Announces Fourth Quarter and Full Year 2023 Financial Results - Gilead Sciences
  2. TYBOST® (cobicistat) tablets, for oral use - Gilead Sciences
  3. Q4 & FY23 Financial Results - Gilead Sciences
  4. Tybost: Package Insert / Prescribing Information - Drugs.com

More… ↓

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